Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Cold/flu Medicine)		[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Acetylsalicylic acid
(Alka-Seltzer Plus Day Non Drowsy Cold Medicine Citrus)		[2] ACETYLSALICYLIC ACID; Aspirin[1] Aspirin 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
3 Allantoin
(Orajel Multi-action Cold Sore Medicine)		[1] ALLANTOIN[1] Allantoin 💬 --[1] 36 💬
4 Bisacodyl
(The Medicine Shoppe Gentle Laxative)		[1] Bisacodyl[1] Bisacodyl 💬 --[1] 13 💬
5 Butylene glycol
(Chinese medicine patch)		[0] [1] Butylene glycol 💬 --[2] 28, 56 💬
6 Caffeine
(Only For FIRST AID MEDICINE)		[1] Caffeine[2] Caffeine ,
Caffeine hydrate 💬 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
7 Calcium carbonate
(Welly Childrens Travel Medicine)		[3] Calcio carbonato; Calcium; Calcium carbonate[2] Calcium carbonate ,
Calcium carbonate 💬 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
8 Chlorpheniramine
(XL-3 Cold Medicine)		[1] Clorfenamina[1] Chlorphenamine 💬 [1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14 💬
9 Citric acid
(Premier Value Antacid and Pain Relief Medicine)		[1] Citric acid[1] Citric acid monohydrate 💬 --[2] 53, 291 💬
10 Dextromethorphan
(Cold/flu Medicine)		[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[1] Dextromethorphan 💬 [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
11 Diphenhydramine
(Pain Relief Medicine PM)		[2] Diphenhydramine; Diphenhydramine hydrochloride[1] Diphenhydramine 💬 [1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256 💬
12 Ibuprofen
(Ibuprofen Fast relief medicine for pain)		[2] Ibuprofen; IBUPROFEN 200MG[1] Ibuprofen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299 💬
13 Loperamide
(Welly Travel Medicine Kit)		[2] Loperamide; Loperamide hydrochloride[1] Loperamide 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97 💬
14 Loratadine
(Medicine Shoppe Allergy Relief D24)		[2] Loratadina; Loratadine[1] Loratadine 💬 [1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98 💬
15 Petrolatum
(Orajel Multi-action Cold Sore Medicine)		[1] Petrolatum[1] Petrolatum 💬 --[1] 158 💬
16 Phenylephrine
(XL-3 Cold Medicine)		[1] Phenylephrine[1] Phenylephrine 💬 [3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22 💬
17 Pseudoephedrine
(Cold and Flu Medicine - Day Time Formula)		[1] Pseudoephedrine[1] Pseudoephedrine 💬 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
18 Sodium bicarbonate
(Premier Value Antacid and Pain Relief Medicine)		[1] Sodium Bicarbonate[1] Sodium bicarbonate 💬 --[1] 299 💬