Drug Description in Trials / DrugBank / KEGG DRUG

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No.

DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

Atropine
(Re-PB Hyos Elixir)

[2] Atropina; Atropine

[1] Atropine 💬

[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬

Name	Full Name
CHRM1	cholinergic receptor muscarinic 1
CHRM2	cholinergic receptor muscarinic 2
CHRM3	cholinergic receptor muscarinic 3
CHRM4	cholinergic receptor muscarinic 4
CHRM5	cholinergic receptor muscarinic 5

[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬

[2] 2, 299 💬

2

Caffeine
(Cafergot Pb Tab)

[2] Caffeine ,
Caffeine hydrate 💬

[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬

Name	Full Name
ADORA1	adenosine A1 receptor
ADORA2A	adenosine A2a receptor
PDE1B	phosphodiesterase 1B
PDE2A	phosphodiesterase 2A
PDE3A	phosphodiesterase 3A
PDE3B	phosphodiesterase 3B
PDE4A	phosphodiesterase 4A
PDE4B	phosphodiesterase 4B
PDE4C	phosphodiesterase 4C
PDE4D	phosphodiesterase 4D
PDE5A	phosphodiesterase 5A

[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[8] 2, 6, 21, 46, 78, 96, 97, 265 💬

3

Ethanol
(Anti-Bacterial Hand PB and J)

[3] Alcohol; Ethanol; PREDNISONE

[1] Ethanol 💬

-

-

[5] 58, 97, 279, 280, 298 💬

Disease ID	Name
58	Hypertrophic cardiomyopathy
97	Ulcerative colitis
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
280	Huge arteriovenous malformation with cervicofacial or limb lesion
298	Hereditary pancreatitis

4

Scopolamine
(Re-PB Hyos Elixir)

[1] Scopolamine

[1] Scopolamine 💬

[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬

Name	Full Name
CHRM1	cholinergic receptor muscarinic 1
CHRM2	cholinergic receptor muscarinic 2
CHRM3	cholinergic receptor muscarinic 3
CHRM4	cholinergic receptor muscarinic 4
CHRM5	cholinergic receptor muscarinic 5

[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬

[1] 2 💬

5

Sildenafil
(Pb-sildenafil)

[6] Mysildecard; Revatio; Sildenafil; Sildenafil citrate; SILDENAFILO; Viagra

[1] Sildenafil 💬

[1] PDE5A 💬

[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬

[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬

Disease ID	Name
6	Parkinson disease
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
113	Muscular dystrophy
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia
225	Congenital nephrogenic diabetes insipidus
226	Interstitial cystitis with Hunners ulcer
278	Huge lymphatic malformation with cervicofacial lesion
294	Congenital diaphragmatic hernia
299	Cystic fibrosis
301	Macular dystrophy

6

Sodium fluoride
(Biotene PBF)

[1] Sodium fluoride

[1] Sodium fluoride 💬

-

-

[1] 51 💬