Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Amphotericin B 💬[1] Amphotericin B (Amphotec 100 mg)[2] ABELCET; Amphotericin B--[1] 299 💬
2 Ascorbic acid 💬[1] Ascorbic acid (Vitamin C 100 Mg Orange Chewable)[4] Acidum ascorbicum; Ascorbic Acid; Iron; Vitamin C--[8] 10, 97, 192, 206, 210, 211, 212, 298 💬
3 Atenolol 💬[1] Atenolol (Riva-atenolol 100 mg)[1] ATENOLOL[1] ADRB1 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
4 Carbamazepine 💬[1] Carbamazepine (Tegretol Chewtabs 100 mg)[1] Carbamazepine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 6, 13, 231 💬
5 Carbidopa 💬[1] Carbidopa (Nu-levocarb - Tab 25 Mg/100 mg)[8] CARBIDOPA; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] DDC 💬 [9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
6 Celecoxib 💬[1] Celecoxib (Celecoxib 100 mg)[2] Celebrex; Celecoxib[1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
7 Fenofibrate 💬[1] Fenofibrate (Lipidil Supra 100 mg)[1] Fenofibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
8 Flurbiprofen 💬[1] Flurbiprofen (Ansaid Tablets 100 mg)[1] FLURBIPROFEN[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46 💬
9 Hydrochlorothiazide 💬[1] Hydrochlorothiazide (Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg)[2] Esidrix; HYDROCHLOROTHIAZIDE[1] SLC12A3 💬 [1] 💬[4] 13, 67, 225, 235 💬
10 Levodopa 💬[1] Levodopa (Nu-levocarb - Tab 25 Mg/100 mg)[9] Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[6] 6, 17, 90, 140, 164, 201 💬
11 Losartan 💬[1] Losartan (LOSARTAN POTASSIUM 100 mg)[3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
12 Metoprolol 💬[1] Metoprolol (Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg)[2] Metoprolol; METOPROLOL SUCCINATE[1] ADRB1 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
13 Morphine 💬[1] Morphine (PMS-morphine Sulfate SR 100 mg)[2] Morphine; Morphine Sulfate[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 36, 46, 70, 85, 86 💬
14 Niacin 💬[1] Niacin (Niacin 100 Mg Tablets)[2] Niacin; Nicotinic acid--[3] 6, 78, 79 💬
15 Niacinamide 💬[1] Nicotinamide (Niacinamide 100 Mg Tablets)[3] Multivitamin; Niacinamide; Nicotinamide--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
16 Pyridoxine 💬[1] Pyridoxine (Vitamin B6 100 mg)[2] Pyridoxine; Vitamin B6--[5] 6, 93, 145, 206, 320 💬
17 Riboflavin 💬[1] Riboflavin (Vitamin B2 100 mg)[2] Riboflavin; Vitamin B2--[7] 38, 46, 96, 97, 162, 168, 265 💬
18 Spironolactone 💬[1] Spironolactone (Aldactone 100 mg)[1] Spironolactone[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[8] 46, 58, 67, 86, 113, 210, 218, 225 💬
19 Theophylline 💬[1] Theophylline (Theo-dur 100 mg)[1] Theophylline[18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299 💬
20 Theophylline 💬[1] Theophylline (Theo-dur 100 mg)[1] Theophylline[18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299 💬
21 Thiamine 💬[1] Thiamine (Vitamin B-1 100 Mg Tablets)[2] Thiamine; Vitamin B1--[4] 8, 93, 145, 265 💬
22 Tranexamic acid 💬[1] Tranexamic acid (Cyklokapron 100 mg/ml)[1] Tranexamic Acid[1] PLG 💬 [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[7] 46, 70, 215, 227, 274, 288, 299 💬
23 Ubidecarenone 💬[1] Ubidecarenone (Coenzyme Q10 100 mg)[3] Coenzyme Q-10; Coenzyme Q10; CoQ10--[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬