Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Edetic acid [1] Edetic acid[1] EDTA; --[1] 60
2 Epinephrine [1] Epinephrine[3] Epinephrine; Lidocaine; Xylocaine; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 46, 70, 96
3 Estradiol [1] Estradiol[1] Estradiol; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299
4 Epoprostenol [1] Epoprostenol[6] EPOPROSTENOL; Epoprostenol for injection; EPOPROSTENOL SODIUM; Flolan; Prostacyclin; Veletri; [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
5 Ephedrine [1] Ephedrine[3] Efedrina; Ephedrine; EPHEDRINE HYDROCHLORIDE; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11
6 Etoposide [1] Etoposide[1] Etoposide; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
7 Erythromycin [1] Erythromycin[1] Erythromycin; --[5] 6, 36, 164, 228, 291
8 Estriol [1] Estriol[1] Estriol; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 13, 227
9 Ergocalciferol [1] Ergocalciferol[3] Ergocalciferol; Vitamin D; Vitamin D2; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299
10 Etodolac [1] Etodolac[1] Etodolac; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
11 Etomidate [1] Etomidate[1] Etomidate; [1] GABRA1 💬[6] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[1] 6
12 Ethinyl estradiol [1] Ethinylestradiol[3] Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 777; [1] ESR1 💬[9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 13, 46, 49, 299
13 Etanercept [1] Etanercept[4] Benepali; Enbrel; Erelzi; Etanercept; [2] LTA,
TNF 💬		[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
14 Entacapone [1] Entacapone[5] COMTAN; Comtess; ENTACAPONA; Entacapone; Stalevo; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17
15 Efavirenz [1] Efavirenz[2] Efavirenz; SUSTIVA; --[1] 265
16 Exametazime [1] Exametazime[1] Exametazime; --[1] 6
17 Eplerenone [1] Eplerenone[1] Eplerenone; [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[4] 75, 113, 210, 215
18 Emtricitabine [1] Emtricitabine[2] Emtricitabine; TRUVADA; --[4] 25, 93, 265, 325
19 Ethamsylate [1] Etamsylate[1] ETAMSYLATE; --[1] 227
20 Estradiol valerate [1] Estradiol valerate[1] Estradiol valerate; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 65
21 Edaravone [1] Edaravone[3] Edaravone; Methylphenylpyrazolone; Norphenazone; --[3] 2, 6, 22
22 Ether [1] Diethyl ether[1] Ether; --[1] 235
23 Ezetimibe [1] Ezetimibe[2] Ezetimibe; Ezetrol; [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
24 Estriol tripropionate [1] Estriol[1] Estriol; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 13, 227
25 Ethanolamine oleate [1] Ethanolamine oleate[1] Ethanolamine oleate; --[1] 279
26 Etidronic acid [1] Etidronic acid[1] Etidronate; --[1] 27
27 Enfuvirtide [1] Enfuvirtide[1] Enfuvirtide; --[2] 25, 265
28 Eszopiclone [1] Eszopiclone[2] Eszopiclone; Zopiclone; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46
29 Everolimus [1] Everolimus[4] Afinitor; Certican; Everolimus; Votubia; [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[9] 34, 67, 89, 96, 137, 157, 158, 228, 277
30 Etoricoxib [1] Etoricoxib[1] ETORICOXIB; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 46, 271
31 Eculizumab [1] Eculizumab[2] Eculizumab; SOLIRIS; [1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222
32 Edratide [1] Edratide[1] Edratide; --[1] 49
33 Efalizumab [1] Efalizumab[2] Efalizumab; Raptiva; [1] ITGAL 💬[12] Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
34 Entecavir [1] Entecavir[1] Entecavir; --[6] 46, 56, 96, 97, 107, 271
35 Epratuzumab [1] Epratuzumab[1] EPRATUZUMAB; [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
36 Erythrityl tetranitrate [1] Erythrityl tetranitrate[0] [2] NPR1,
NPR2 💬		[10] Aldosterone synthesis and secretion, Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 46
37 Estrogens, conjugated [1] Conjugated estrogens[1] Conjugated equine estrogens; --[1] 49
38 Ethiodized oil [1] Ethiodized oil[1] Lipiodol; --[1] 280
39 Ethiodized oil I 131 [1] Ethiodized oil[1] Lipiodol; --[1] 280
40 Etiprednol dicloacetate [1] Etiprednol dicloacetate[1] Etiprednol dicloacetate; --[1] 96
41 Etravirine [1] Etravirine[3] ETRAVIRINA; Etravirine; INTELENCE; --[1] 18
42 Exenatide [1] Exenatide[3] BYDUREON; Byetta; EXENATIDE; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233
43 Ethanol [1] Ethanol[3] Alcohol; Ethanol; PREDNISONE; --[5] 58, 97, 279, 280, 298
44 Esketamine [1] Esketamine[3] Esketamine; KETAMINE; S-ketamine; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 4, 70
45 Eldecalcitol [1] Eldecalcitol[1] Eldecalcitol; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 46
46 Eflornithine [1] Eflornithine[1] Eflornithine; [1] ODC1 💬[3] Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways 💬[1] 65
47 Enalapril [1] Enalapril[2] Enalapril; Enalapril Maleate; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
48 Entecavir [1] Entecavir[1] Entecavir; --[6] 46, 56, 96, 97, 107, 271
49 Eperisone [1] Eperisone[1] EPERISONE; --[1] 2
50 Erlotinib [1] Erlotinib[1] Erlotinib; [1] EGFR 💬[48] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬[1] 94
51 Escitalopram [1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46
52 Esmolol [1] Esmolol[1] Esmolol; [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 58
53 Esomeprazole [1] Esomeprazole[3] Esomeprazole; Nexium; Omeprazole; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299
54 Ethambutol [1] Ethambutol[1] Ethambutol; --[2] 84, 299
55 Elotuzumab [1] Elotuzumab[1] Elotuzumab; [1] SLAMF7 💬-[1] 28
56 Ezogabine [1] Ezogabine[4] Ezogabine; Potiga; RETIGABINE; Trobalt; [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬		[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144
57 Edoxaban [1] Edoxaban[1] Edoxaban; [1] F10 💬[1] Complement and coagulation cascades 💬[2] 46, 88
58 Eliglustat [1] Eliglustat[2] Cerdelga; Eliglustat; [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19
59 Eteplirsen [1] Eteplirsen[2] ETEPLIRSEN; Exondys 51; [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
60 Etrolizumab [1] Etrolizumab[1] ETROLIZUMAB; [1] ITGB7 💬[11] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer 💬[2] 96, 97
61 Elosulfase alfa [1] Elosulfase alfa[3] Elosulfase alfa; Recombinant human N-acetylgalactosamine-6-sulfatase; RhGALNS; [1] GALNS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
62 Emixustat [1] Emixustat[1] Emixustat; --[1] 301
63 Empagliflozin [1] Empagliflozin[2] Empagliflozin; Jardiance; [1] SLC5A2 💬-[6] 58, 65, 67, 72, 97, 257
64 Evolocumab [1] Evolocumab[2] EVOLOCUMAB; Repatha; [1] PCSK9 💬[1] Cholesterol metabolism 💬[2] 79, 222
65 Elobixibat [1] Elobixibat[1] Elobixibat; [1] SLC10A2 💬[1] Bile secretion 💬[1] 6
66 Emicizumab [1] Emicizumab[2] Emicizumab; Hemlibra; [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
67 Elamipretide [1] Elamipretide[1] Elamipretide; --[2] 21, 324
68 Etrasimod [1] Etrasimod[1] Etrasimod; [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 96, 97, 98
69 Emapalumab [1] Emapalumab[1] EMAPALUMAB; [1] IFNG 💬[32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[3] 49, 65, 107
70 Eleclazine [1] Eleclazine[1] Eleclazine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 58
71 Elafibranor [1] Elafibranor[1] Elafibranor; [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94
72 Elezanumab [1] Elezanumab[1] Elezanumab; [1] RGMA 💬[2] Axon guidance, TGF-beta signaling pathway 💬[1] 13
73 Elexacaftor [1] Elexacaftor[3] ELEXACAFTOR; Kaftrio; Trikafta; [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
74 Estetrol [1] Estetrol[1] Estetrol; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 53
75 Estetrol [1] Estetrol[1] Estetrol; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 53
76 Efavaleukin alfa [1] Efavaleukin alfa[1] EFAVALEUKIN ALFA; --[2] 49, 97
77 Evinacumab [1] Evinacumab[1] EVINACUMAB; [1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79
78 Efgartigimod alfa [1] Efgartigimod alfa[1] EFGARTIGIMOD ALFA; [1] FCGRT 💬-[6] 11, 14, 35, 53, 63, 162
79 Enzastaurin [1] Enzastaurin[1] Enzastaurin; [1] PRKCB 💬[71] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Amoebiasis, Amphetamine addiction, B cell receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Circadian entrainment, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, EGFR tyrosine kinase inhibitor resistance, Endocrine and other factor-regulated calcium reabsorption, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, GABAergic synapse, Gap junction, Gastric acid secretion, Glioma, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Insulin secretion, Leishmaniasis, Leukocyte transendothelial migration, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, Pancreatic secretion, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phosphatidylinositol signaling system, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Sphingolipid signaling pathway, Spinocerebellar ataxia, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, mTOR signaling pathway 💬[1] 168
80 Efmarodocokin alfa [1] Efmarodocokin alfa[2] Efmarodocokin alfa; IL-22Fc; [1] IL22 💬[4] Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Th17 cell differentiation 💬[2] 96, 97
81 Efineptakin alfa [1] Efineptakin alfa[1] NT-I7; --[1] 25
82 Elasomeran [1] Moderna COVID-19 Vaccine[4] COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax; --[5] 13, 46, 51, 65, 299
83 Elivaldogene autotemcel [1] Elivaldogene autotemcel[1] Elivaldogene autotemcel; [1] ABCD1 💬[2] ABC transporters, Peroxisome 💬[1] 20
84 Edasalonexent [1] Edasalonexent[1] EDASALONEXENT; [1] RELA 💬[76] AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬[1] 113
85 Efanesoctocog alfa [1] Efanesoctocog alfa[1] Efanesoctocog alfa; --[1] 288
86 Evobrutinib [1] Evobrutinib[1] Evobrutinib; [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 13, 46, 49