Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Oxygen [1] Oxygen[3] Medical air; Nitrogen; Oxygen; --[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
2 Oxiglutatione [1] Glutathione[2] GLUTATHIONE; Reduced glutathione; --[2] 6, 299
3 Oxytocin [1] Oxytocin[2] Oxytocin; Syntocinon; [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226
4 Octreotide [1] Octreotide[3] Octreotide; OCTREOTIDE ACETATE; Sandostatin LAR; [1] SSTR2 💬[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[7] 67, 75, 84, 85, 89, 193, 227
5 Olanzapine [1] Olanzapine[2] OLANZAPINE; Zyprexa; [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
6 Omeprazole [1] Omeprazole[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
7 Ondansetron [1] Ondansetron[1] Ondansetron; [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107
8 Oxandrolone [1] Oxandrolone[1] Oxandrolone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 211, 285
9 Oxybutynin [1] Oxybutynin[1] Oxybutynin; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53
10 Oxcarbazepine [1] Oxcarbazepine[2] Oxcarbazepine; Trileptal; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13
11 Oxatomide [1] Oxatomide[1] Oxatomide; [1] ALOX5 💬[6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113
12 Oleic acid [1] Oleic Acid[1] Oleic Acid; --[2] 13, 299
13 Olive oil [1] Olive oil[1] Olive Oil; --[5] 13, 35, 49, 53, 162
14 Ocrelizumab [1] Ocrelizumab[3] Ocrelizumab; OCREVUS; RhuMAb 2H7; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 13, 46, 49
15 Omalizumab [1] Omalizumab[2] Omalizumab; XOLAIR; [1] FCER1A 💬[4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299
16 Oprelvekin [1] Oprelvekin[5] IL-11; Interleukin 11; Interleukin-11; Oprelvekin; Recombinant interleukin-11; [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[2] 96, 288
17 Oxycodone [1] Oxycodone[2] Oxycodone; OXYCODONE HYDROCHLORIDE; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298
18 Oxyquinoline [1] Oxyquinoline[1] Oxine; --[1] 13
19 Olsalazine [1] Olsalazine[1] Olsalazine; --[1] 271
20 Ornithine [1] Ornithine[1] Ornithine; --[2] 245, 251
21 Oseltamivir [1] Oseltamivir[1] Oseltamivir; --[2] 97, 299
22 Oxiconazole [1] Oxiconazole[1] Oxiconazole; --[1] 160
23 Oxybuprocaine [1] Oxybuprocaine[1] Oxybuprocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6
24 Oxymorphone [1] Oxymorphone[1] Opana; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70
25 Otelixizumab [1] Otelixizumab[1] Otelixizumab; [3] CD3D,
CD3E,
CD3G 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46
26 Ofatumumab [1] Ofatumumab[4] Arzerra; HuMax-CD20; Kesimpta; Ofatumumab; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 13, 35, 46
27 Obinutuzumab [1] Obinutuzumab[2] GAZYVARO; OBINUTUZUMAB; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[4] 43, 44, 49, 222
28 Obeticholic acid [1] Obeticholic acid[4] 6-ECDCA; 6-ethylchenodeoxycholic acid; OBETICHOLIC ACID; Ocaliva; [1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296
29 Omadacycline [1] Omadacycline[1] Omadacycline; --[1] 299
30 Orvepitant [1] Orvepitant[1] ORVEPITANT; [1] TACR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 85
31 Olaparib [1] Olaparib[1] Olaparib; [2] PARP1,
PARP2 💬		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285
32 Ozoralizumab [1] Ozoralizumab[1] Ozoralizumab; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
33 Ozanezumab [1] Ozanezumab[1] Ozanezumab; [1] RTN4 💬[1] Alzheimer disease 💬[1] 2
34 Olipudase alfa [1] Olipudase alfa[1] OLIPUDASE ALFA; [1] SMPD1 💬[5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19
35 Opicapone [1] Opicapone[2] Ongentys; OPICAPONE; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6
36 Omaveloxolone [1] Omaveloxolone[1] Omaveloxolone; [1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18
37 Ozanimod [1] Ozanimod[2] Ozanimod; Zeposia; [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97
38 Osilodrostat [1] Osilodrostat[1] OSILODROSTAT; [1] CYP11B2 💬[3] Aldosterone synthesis and secretion, Metabolic pathways, Steroid hormone biosynthesis 💬[1] 75
39 Olesoxime [1] Olesoxime[1] OLESOXIME; --[3] 2, 3, 13
40 Otilimab [1] Otilimab[1] OTILIMAB; [1] CSF2 💬[16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[1] 46
41 Obexelimab [1] Obexelimab[1] Obexelimab; [1] CD19 💬[5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[1] 300
42 Onasemnogene abeparvovec [1] Onasemnogene abeparvovec[3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma; [1] SMN1 💬-[1] 3
43 Odevixibat [1] Odevixibat[1] Odevixibat; [1] SLC10A2 💬[1] Bile secretion 💬[3] 296, 297, 338
44 Opicinumab [1] Opicinumab[1] Opicinumab; [1] LINGO1 💬-[1] 13
45 Orilanolimab [1] Orilanolimab[1] ORILANOLIMAB; [1] FCGRT 💬-[1] 61
46 Orelabrutinib [1] Orelabrutinib[1] Orelabrutinib; [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63
47 Olokizumab [1] Olokizumab[1] Olokizumab; [1] IL6 💬[51] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 46, 96