Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen 💬[1] Acetaminophen (Acetaminophen With Antihistamine Nighttime)[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Cetirizine 💬[1] Cetirizine (Picnic Antihistamine)[3] CETIRIZINA; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300 💬
3 Chlorphenamine 💬[1] Chlorpheniramine (Sun Mark Allergy Antihistamine)[1] Clorfenamina[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14 💬
4 Dextromethorphan 💬[1] Dextromethorphan (Antitussive Decong Antihistamine Syr)[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
5 Diphenhydramine 💬[1] Diphenhydramine (Diphenhydramine HCl Allergy Antihistamine)[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256 💬
6 Ferric oxide 💬[1] Ferric oxide (Calamine Lotion With Antihistamine)[1] Iron oxide--[1] 13 💬
7 Fexofenadine 💬[1] Fexofenadine (Picnic Antihistamine)[1] Fexofenadine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 46 💬
8 Loratadine 💬[1] Loratadine (Loratadineantihistamine antihistamine)[2] Loratadina; Loratadine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98 💬
9 Pseudoephedrine 💬[1] Pseudoephedrine (Picnic Nasal Decongestant and Antihistamine)[1] Pseudoephedrine[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
10 Zinc oxide 💬[1] Zinc oxide (Calamine Lotion With Antihistamine)[1] Zinc oxide--[1] 156 💬