Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen 💬[1] Acetaminophen (Tempra Infant Drops)[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Allantoin 💬[1] Allantoin (Optrex Eye Drops)[1] ALLANTOIN--[1] 36 💬
3 Amoxicillin 💬[1] Amoxicillin (Amoxil Pediatric Drops Pws 50mg/ml)[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
4 Amoxicillin 💬[1] Amoxicillin (Amoxil Pediatric Drops Pws 50mg/ml)[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
5 Ascorbic acid 💬[1] Ascorbic acid (Multivitamin Drops with Fluoride)[4] Acidum ascorbicum; ASCORBIC ACID; Iron; Vitamin C--[8] 10, 97, 192, 206, 210, 211, 212, 298 💬
6 Betamethasone 💬[1] Betamethasone (Betnesol Eye and Ear Drops)[1] Betamethasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[8] 2, 28, 46, 65, 83, 90, 96, 235 💬
7 Biotin 💬[1] Biotin (Quflora FE Pediatric Drops)[4] Biotin; Biotina; D-BIOTIN; Vitamin B7--[5] 2, 8, 10, 13, 20 💬
8 Brimonidine 💬[1] Brimonidine (LUMIFY Redness Reliever Eye Drops)[2] Brimonidine; Brimonidine tartrate[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 13, 90 💬
9 Caffeine 💬[1] Caffeine (SMITH BROS WILD CHERRY DAY TIME with Caffeine Soothing Drops)[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
10 Caffeine hydrate 💬[1] Caffeine (SMITH BROS WILD CHERRY DAY TIME with Caffeine Soothing Drops)[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
11 Chlorphenamine 💬[1] Chlorpheniramine (Neutrahist Pediatric Drops)[1] Clorfenamina[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14 💬
12 Chlorpromazine 💬[1] Chlorpromazine (Largactil Drops 40mg/ml)[2] Chlorpromazine; Chlorpromazine Hydrochloride[13] ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬 		[22] Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 254 💬
13 Cholecalciferol 💬[1] Cholecalciferol (YYUX Organic Liquid Vitamin D3 Drops For Kids 4 plus years 600 IU)[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
14 Cromoglicic acid 💬[1] Cromoglicic acid (Anti-allergy Eye Drops)[4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium--[3] 2, 85, 98 💬
15 Cyanocobalamin 💬[1] Cyanocobalamin (Quflora Pediatric Drops)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
16 Cyanocobalamin Co 57 💬[1] Cyanocobalamin (Quflora Pediatric Drops)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
17 Cyanocobalamin Co 58 💬[1] Cyanocobalamin (Quflora Pediatric Drops)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
18 Cyanocobalamin Co 60 💬[1] Cyanocobalamin (Quflora Pediatric Drops)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
19 Dextran 1 💬[1] Dextran (Signature Care Eye Drops Advanced Relief)[1] Dextran--[4] 2, 62, 96, 97 💬
20 Dextromethorphan 💬[1] Dextromethorphan (Panatuss Pediatric Drops DXP)[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
21 Dorzolamide 💬[1] Dorzolamide (Dorzolamide Eye Drops BP)[1] Dorzolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90 💬
22 Ergocalciferol 💬[1] Ergocalciferol (Aquasol A & D Drops)[3] Ergocalciferol; Vitamin D; Vitamin D2[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299 💬
23 Erythromycin 💬[1] Erythromycin (EryPed Drops)[1] Erythromycin--[5] 6, 36, 164, 228, 291 💬
24 Ethanol 💬[1] Ethanol (Nature Drops Hand Sanitizer)[3] Alcohol; Ethanol; PREDNISONE--[5] 58, 97, 279, 280, 298 💬
25 Fluocinolone acetonide 💬[1] Fluocinolone acetonide (Dermotic Oil Ear Drops)[2] Fluocinolone Acetonide; Iluvien[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 90 💬
26 Folic acid 💬[1] Folic acid (Vigo Multivitamins Drops/lozenge)[5] Acide folique; Folate; Folic acid; Multivitamin; Nicotinamide--[6] 6, 41, 46, 49, 84, 296 💬
27 Glycerin 💬[1] Glycerin (GNP Eye Drops Redness and Dry Eye Relief)[2] Bee venom; Glycerol--[5] 6, 13, 79, 316, 317 💬
28 Hyaluronic acid 💬[1] Hyaluronic acid (Lubricant Eye Drops)[2] Hyaluronate; Hyaluronic acid--[6] 46, 53, 70, 97, 226, 231 💬
29 Hydrocortisone 💬[1] Hydrocortisone (Oticin HC Ear Drops)[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
30 Hydrocortisone acetate 💬[1] Hydrocortisone acetate (Neo-cortef Eye Ear Drops Sterile Suspension)[2] Hydrocortisone; HYDROCORTISONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 97 💬
31 Ibuprofen 💬[1] Ibuprofen (Infants Advil Concentrated Drops)[2] Ibuprofen; IBUPROFEN 200MG[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299 💬
32 Levomefolic acid 💬[1] Levomefolic acid (Quflora FE Pediatric Drops)[1] L-methylfolate--[1] 6 💬
33 Lidocaine 💬[1] Lidocaine (Lidosporin Ear Drops)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
34 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine (Lidosporin Ear Drops)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
35 Magnesium oxide 💬[1] Magnesium oxide (Quflora Pediatric Drops)[1] Magnesium oxide--[3] 6, 166, 291 💬
36 Mineral oil 💬[1] Mineral oil (Walgreens Lubricant Eye Drops Preservative Free)[1] Paraffin Oil--[1] 291 💬
37 Morphine 💬[1] Morphine (Statex Drops 20mg/ml)[2] Morphine; MORPHINE SULFATE[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 36, 46, 70, 85, 86 💬
38 Neomycin 💬[1] Neomycin (Neo-cortef Eye Ear Drops Sterile Suspension)[1] Neomycin--[3] 96, 97, 296 💬
39 Niacin 💬[1] Niacin (Multi-Vitamin Fluoride Drops)[2] Niacin; Nicotinic acid--[3] 6, 78, 79 💬
40 Niacinamide 💬[1] Nicotinamide (Multi Vitamin Drops with Fluoride and Iron)[3] Multivitamin; Niacinamide; NICOTINAMIDE--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
41 Pectin 💬[1] Pectin (Ludens Wild Cherry Throat Drops)[1] Pectin--[1] 96 💬
42 Phenylephrine 💬[1] Phenylephrine (G-tron Pediatric Drops)[1] Phenylephrine[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22 💬
43 Propylene glycol 💬[1] Propylene glycol (Lubricant Eye Drops Long Lasting)[1] Propylene glycol--[1] 51 💬
44 Pseudoephedrine 💬[1] Pseudoephedrine (TRISPEC PSE Pediatric Drops Cough Suppressant Expectorant Nasal Decongestant GRAPE Flavor)[1] Pseudoephedrine[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
45 Pyridoxine 💬[1] Pyridoxine (Multi Vitamin Drops with Fluoride and Iron)[2] Pyridoxine; Vitamin B6--[5] 6, 93, 145, 206, 320 💬
46 Riboflavin 💬[1] Riboflavin (Vigo Multivitamins Drops/lozenge)[2] Riboflavin; Vitamin B2--[7] 38, 46, 96, 97, 162, 168, 265 💬
47 Salicylic acid 💬[1] Salicylic acid (ClearSkinDays Acne Clearing Drops)[2] 2-Hydroxybenzoic acid; Salicylic acid--[1] 97 💬
48 Simethicone 💬[1] Simethicone (Ovol Drops)[1] Simethicone--[2] 13, 96 💬
49 Sodium fluoride 💬[1] Sodium fluoride (Multi Vitamin Drops with Fluoride)[1] Sodium fluoride--[1] 51 💬
50 Thiamine 💬[1] Thiamine (Multi Vitamin Drops with Fluoride with Iron)[2] THIAMINE; Vitamin B1--[4] 8, 93, 145, 265 💬
51 Timolol 💬[1] Timolol (Dorzolamide and Timolol Eye Drops BP)[2] Timolol; TIMOLOL MALEATE[2] ADRB1,
ADRB2 💬 		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227 💬
52 Timolol 💬[1] Timolol (Dorzolamide and Timolol Eye Drops BP)[2] Timolol; TIMOLOL MALEATE[2] ADRB1,
ADRB2 💬 		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227 💬
53 Tocopherol 💬[1] Tocopherol (Multivitamin Drops with Fluoride)[2] Tocoferol; Tocopherol--[6] 13, 49, 90, 206, 257, 298 💬
54 Vitamin A 💬[1] Vitamin A (Multivitamin Drops with Fluoride)[1] Vitamin A[2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90 💬
55 Vitamin E 💬[1] Vitamin E (NovaFerrum Multivitamin with Iron Pediatric Drops)[2] Alpha-tocopherol; Vitamin E--[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
56 Zinc oxide 💬[1] Zinc oxide (Light Medium Tinted Drops)[1] Zinc oxide--[1] 156 💬