Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
2 Asthma 💬
[1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
3 Asthma 💬
[1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
4 Asthma 💬
[1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
5 Asthma 💬
[1] CD40LG 💬 D06193 💬 Toralizumab [1] 63 💬
6 Asthma 💬
[1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
7 Asthma 💬
[2] IL10, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
8 Asthma 💬
[1] IL13 💬 D08857 💬 Anrukinzumab [1] 97 💬
9 Asthma 💬
[1] IL13 💬 D09633 💬 Lebrikizumab [1] 85 💬
10 Asthma 💬
[1] IL13 💬 D09979 💬 Tralokinumab [2] 85, 97 💬
11 Asthma 💬
[1] IL4 💬 D03117 💬 Binetrakin [1] 46 💬
12 Asthma 💬
[1] IL5 💬 D04923 💬 Mepolizumab [4] 44, 45, 98, 162 💬
13 Asthma 💬
[1] IL5 💬 D08985 💬 Reslizumab [2] 44, 98 💬
14 Asthma 💬
[1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
15 Asthma 💬
[1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
16 Asthma 💬
[1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
17 Asthma 💬
[1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
18 Asthma 💬
[1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
19 Asthma 💬
[1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
20 Asthma 💬
[1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
21 Asthma 💬
[1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
22 Asthma 💬
[1] TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
23 Asthma 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
24 Calcium signaling pathway 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
25 cAMP signaling pathway 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
26 cGMP-PKG signaling pathway 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
27 Chemical carcinogenesis - receptor activation 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
28 Neuroactive ligand-receptor interaction 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
29 Regulation of lipolysis in adipocytes 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
30 Renin secretion 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
31 Salivary secretion 💬
[1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬