113. 筋ジストロフィー Muscular dystrophy Clinical trials / Disease details

臨床試験数 : 646 / 薬物数 : 471 - (DrugBank : 105) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 170

5 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01580501 (ClinicalTrials.gov)	March 2012	17/4/2012	PDE Inhibitors in DMD Study (Acute Dosing Study)	Functional Muscle Ischemia and PDE5 Inhibition in Duchenne Muscular Dystrophy: Acute Dosing Study	Duchenne Muscular Dystrophy	Drug: Tadalafil and Sildenafil	Cedars-Sinai Medical Center	NULL	Completed	7 Years	15 Years	Male	12	Phase 1	United States
2	NCT01350154 (ClinicalTrials.gov)	November 2011	4/5/2011	Effect of Modulating the nNOS System on Cardiac, Muscular and Cognitive Function in Becker Muscular ...	Does Modulation of the nNOS System in Patients With Muscular Dystrophy and Defect nNOS Signalling Af ...	Becker Muscular Dystrophy	Drug: Sildenafil;Drug: Placebo	Rigshospitalet, Denmark	Glostrup University Hospital, Copenhagen	Completed	18 Years	80 Years	Male	17	Phase 2	Denmark
3	EUCTR2010-024659-10-DK (EUCTR)	03/08/2011	21/06/2011	Can certain muscle wasting diseases be improved with sildenafil?	Can stimulation of the nNOS system in muscle disease with nNOS insufficiency improve heart and skele ...	Muscular dystrophy with nNOS insufficiency MedDRA version: 14.0;Level: LLT;Classification code 10028 ...	Trade Name: Revatio Product Name: Sildenafil Product Code: EMEA/H/C/000638	Rigshospitalet	NULL	Not Recruiting			Female: no Male: yes			Denmark
4	NCT01359670 (ClinicalTrials.gov)	May 2011	23/5/2011	Tadalafil and Sildenafil for Duchenne Muscular Dystrophy	Functional Muscle Ischemia and PDE5A Inhibition in Duchenne Muscular Dystrophy	Duchenne Muscular Dystrophy	Drug: Tadalafil;Drug: Sildenafil	Cedars-Sinai Medical Center	Parent Project Muscular Dystrophy	Completed	7 Years	15 Years	Male	30	Early Phase 1	United States
5	NCT01168908 (ClinicalTrials.gov)	September 2010	22/7/2010	Revatio for Heart Disease in Duchenne Muscular Dystrophy and Becker Muscular Dystrophy	Phase 2 Clinical Trial of Sildenafilfor Cardiac Dysfunction in Duchenne Muscular Dystrophy and Becke ...	Duchenne Muscular Dystrophy;Becker Muscular Dystrophy	Drug: Sildenafil	Hugo W. Moser Research Institute at Kennedy Krieger, Inc.	Johns Hopkins University	Terminated	18 Years	50 Years	Male	20	Phase 2	United States

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