Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	HRH3	1件: Neuroactive ligand-receptor interaction	D10749	Pitolisant	2件: 113, 193
2	MAPK14	62件: Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D09639	Losmapimod	2件: 113, 222
3	CSF3R	5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03235	Filgrastim	35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 6 ...
4	ADRA1D	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D00255	Carvedilol	4件: 57, 86, 113, 210
5	ADRA1B	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D00255	Carvedilol	4件: 57, 86, 113, 210
6	ADRA1A	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D00255	Carvedilol	4件: 57, 86, 113, 210
7	CCN2	2件: Apelin signaling pathway, Hippo signaling pathway	D10969	Pamrevlumab	2件: 85, 113
8	ADRA2A	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
9	ADRA2B	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
10	ADRA2C	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280

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