274. 骨形成不全症 Osteogenesis Imperfecta Clinical trials / Disease details
臨床試験数 : 91 / 薬物数 : 101 - (DrugBank : 20) / 標的遺伝子数 : 11 - 標的パスウェイ数 : 48
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04545554 (ClinicalTrials.gov) | January 21, 2021 | 4/9/2020 | Study to Evaluate Romosozumab in Children and Adolescents With Osteogenesis Imperfecta | An Open-label, Ascending Multiple-dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Romosozumab in Children and Adolescents With Osteogenesis Imperfecta | Osteogenesis Imperfecta | Drug: Romosozumab;Dietary Supplement: Calcium;Dietary Supplement: Vitamin D | Amgen | NULL | Active, not recruiting | 5 Years | 17 Years | All | 25 | Phase 1 | United States;Austria;Germany;Greece;Hungary;Italy;Spain;Turkey |
| 2 | NCT01713231 (ClinicalTrials.gov) | September 2012 | 21/10/2012 | Effect of High-Dose Vitamin D on Bone Density in Osteogenesis Imperfecta | Effect of High-Dose Vitamin D on Bone Density in Osteogenesis Imperfecta | Osteogenesis Imperfecta | Dietary Supplement: standard-dose vitamin D (400IU per day);Dietary Supplement: high-dose vitamin D (2000 IU per day) | Louis-Nicolas Veilleux Ph.D. | NULL | Completed | 6 Years | 19 Years | Both | 60 | Phase 4 | Canada |