299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details

臨床試験数 : 1,695 / 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

19 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05663255 (ClinicalTrials.gov)	March 1, 2023	15/12/2022	Effectiveness of CFTR Modulators According to Co-therapy	Is Effectiveness of CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Modulators Impacted b ...	Cystic Fibrosis	Drug: Discontinuation of respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)	Hospices Civils de Lyon	NULL	Not yet recruiting	6 Years	N/A	All	1990		NULL
2	ChiCTR2100052906	2022-01-01	2021-11-06	A randomized controlled study of comparing the effect of two azithromycinregimens in reducing exacer ...	A randomized controlled study of comparing the effect of two azithromycinregimens in reducing exacer ...	Bronchiectasis	Daily AzithromycinGroup:Azithromycin250mg QD;Weekly AzithromycinGroup:Azithromycin500mg TIW;Placebo ...	The First People' Hospital of Jiashan	NULL	Recruiting			Both	Daily Azithromycin Group:41;Weekly Azithromycin Group:41;Placebo Group:41;	Phase 4	China
3	EUCTR2016-001440-18-NL (EUCTR)	30/05/2018	16/01/2018	The influence of cytochrome P450 3A4 inhibitors on serum levels of Ivacaftor in cystic fibrosis pati ...	Pharmacokinetic interactions between ivacaftor and cytochrome P450 3A4 inhibitors in cystic fibrosis ...	cystic fibrosis and healthy subjects;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Ne ...	Trade Name: Ivacaftor Trade Name: claritromycin 500mg film coated tablets Product Name: Claritromycin Tr ...	university medical center utrecht	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	12	Phase 4	Netherlands
4	NCT02677701 (ClinicalTrials.gov)	October 21, 2016	29/1/2016	Testing the Effect of Adding Chronic Oral Azithromycinto Inhaled Tobramycin in People With Cystic Fi ...	TEACH Trial: Testing the Effect of Adding CHronic Azithromycinto Inhaled Tobramycin. A Randomized, P ...	Cystic Fibrosis	Drug: azithromycin;Drug: placebo (for azithromycin);Drug: inhaled tobramycin	Seattle Children's Hospital	National Heart, Lung, and Blood Institute (NHLBI);Cystic Fibrosis Foundation;CF Therapeutics Develop ...	Completed	12 Years	N/A	All	119	Phase 4	United States
5	NCT02531984 (ClinicalTrials.gov)	August 2015	21/8/2015	The Efficacy of Azithromycin in Treating Children With Non Cystic Fibrosis Bronchiectasis	Open Trial With Randomized Withdrawal of Treatment, to Evaluate the Efficacy of Azithromycinin the T ...	Non Cystic Fibrosis Bronchiectasis in Children	Drug: Azithromycin	Assistance Publique Hopitaux De Marseille	NULL	Active, not recruiting	3 Years	17 Years	Both	100	Phase 3	NULL
6	NCT02372383 (ClinicalTrials.gov)	October 2014	20/6/2014	Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis	Pharmacokinetic Evaluation of Nontuberculous Mycobacterial Antibiotics in Cystic Fibrosis Versus Con ...	Cystic Fibrosis	Drug: Ethambutol;Drug: Rifampin;Drug: Azithromycin;Drug: Pancrelipase	University of Colorado, Denver	Cystic Fibrosis Foundation Therapeutics;Colorado Clinical & Translational Sciences Institute	Completed	16 Years	45 Years	Both	32	N/A	United States
7	NCT02803944 (ClinicalTrials.gov)	September 2014	14/6/2016	Continuous Azithromycin in Cystic Fibrosis Patients Beyond Two Years	Long Term Effects of Azithromycin in Patients With Cystic Fibrosis Using the National Database	Cystic Fibrosis	Drug: Azithromycin	Hospices Civils de Lyon	NULL	Completed	7 Years	N/A	Both	2055	N/A	France
8	NCT02054156 (ClinicalTrials.gov)	June 2014	1/2/2014	OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis	OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis: The OPTIMIZE Mul ...	Cystic Fibrosis	Drug: azithromycin;Drug: placebo;Drug: Tobramycin solution for inhalation	Bonnie Ramsey	National Heart, Lung, and Blood Institute (NHLBI)	Completed	6 Months	18 Years	All	221	Phase 3	United States
9	NCT01270074 (ClinicalTrials.gov)	April 2012	23/12/2010	Prevention of Bronchiectasis in Infants With Cystic Fibrosis	A Phase 3 Multi-centre Randomised Placebo-controlled Study of Azithromycinin the Primary Prevention ...	Cystic Fibrosis;Bronchiectasis	Drug: Azithromycin;Drug: Placebo control	The University of Queensland	Telethon Kids Institute	Completed	6 Weeks	6 Months	All	130	Phase 3	Australia;New Zealand
10	NCT03045198 (ClinicalTrials.gov)	March 2012	2/2/2017	Effect of Azithromycin on Fatty Acids in CF	Effect of Azithromycin on Lipoproteins and Docosahexaenoic Acid in Patients With Cystic Fibrosis	Cystic Fibrosis	Drug: Azithromycin	University Childrens' Hospital (Zentrum für Kinderheilkunde des Universitätsklinikum Bonn)	University of Bonn;University Hospital, Frankfurt	Unknown status	10 Years	60 Years	All	20	Phase 4	NULL

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