Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
ABCC8 1件: ABCC8 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
2 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
3 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
4 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
5 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
6 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
7 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
8 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
RARA 1件: RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
9 | Adherens junction 💬 Related to 9 target genes, 19 drugs (DrugBank) and 23 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
10 | Adherens junction 💬 Related to 9 target genes, 19 drugs (DrugBank) and 23 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
11 | Adherens junction 💬 Related to 9 target genes, 19 drugs (DrugBank) and 23 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
12 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
13 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
14 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
15 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
16 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
17 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
18 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
19 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
20 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
21 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
22 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
23 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
24 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
25 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
26 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
27 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
28 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
29 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
30 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
SCNN1A 3件: SCNN1A, SCNN1B, SCNN1G 💬 |
D07447 D07447 💬 |
Amiloride | 013 4件: 13, 67, 225, 299 💬 |
31 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
32 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
33 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
34 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
35 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
36 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
37 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
38 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
39 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
40 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
41 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
42 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
43 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
44 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
45 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
46 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
47 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
48 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
49 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
50 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
51 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
52 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
53 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
54 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
55 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
56 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
57 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
58 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
59 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
60 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
61 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
62 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
CTSC 1件: CTSC 💬 |
D12120 D12120 💬 |
Brensocatib | 299 1件: 299 💬 |
63 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
64 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
65 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
66 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
67 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
68 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
69 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
70 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
71 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
72 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
73 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
74 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
75 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
76 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
77 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
78 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
79 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
80 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
81 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
82 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
NR1H4 1件: NR1H4 💬 |
D00734 D00734 💬 |
Ursodeoxycholic acid | 006 14件: 6 , 8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬 |
83 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
84 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
85 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
86 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 4件: 13, 46, 49, 299 💬 |
87 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 1件: 299 💬 |
88 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
89 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
90 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
91 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
92 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
93 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADORA2B 4件: ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
94 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADORA2B 4件: ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
95 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
96 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
97 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
98 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
99 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AVPR1A 2件: AVPR1A, AVPR1B 💬 |
D06672 D06672 💬 |
Terlipressin | 299 1件: 299 💬 |
100 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CHRM1 4件: CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
101 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CHRM2 2件: CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
102 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
103 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
DRD1 2件: DRD1, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
104 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
105 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
106 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PTGFR 1件: PTGFR 💬 |
D06274 D06274 💬 |
Tafluprost | 299 1件: 299 💬 |
107 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADORA1 8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
108 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADORA1 8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
109 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
110 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
111 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
112 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
113 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
114 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
115 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
116 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
117 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
118 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
119 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
120 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CHRM2 1件: CHRM2 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
121 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD1 3件: DRD1, DRD2, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
122 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D09889 D09889 💬 |
Dulaglutide | 013 2件: 13, 299 💬 |
123 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
124 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
125 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
126 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
127 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
128 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADORA1 4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
129 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADORA1 4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
130 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
131 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
132 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
133 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
134 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
135 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
136 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
137 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
138 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
139 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 3件: 13, 86, 299 💬 |
140 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
141 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
142 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
143 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
144 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
145 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
146 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
147 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
148 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
149 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PGR 1件: PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 4件: 13, 46, 49, 299 💬 |
150 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PGR 1件: PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 1件: 299 💬 |
151 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
152 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
153 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR 1件: VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 2件: 113, 299 💬 |
154 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
155 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR 1件: VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 |
156 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
CXCR1 2件: CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 2件: 298, 299 💬 |
157 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
158 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
159 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM2 2件: CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
160 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
161 | Circadian rhythm 💬 Related to 2 target genes, 1 drug (DrugBank) and 25 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
162 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
163 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
164 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
165 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
166 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
167 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
SERPINC1 1件: SERPINC1 💬 |
D07510 D07510 💬 |
Heparin | 047 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬 |
168 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
169 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
170 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
171 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
172 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
173 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
PDE11A 3件: PDE11A, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
174 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
PDE11A 3件: PDE11A, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
175 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D05066 D05066 💬 |
Molgramostim | 097 3件: 97, 229, 299 💬 |
176 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CXCR1 2件: CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 2件: 298, 299 💬 |
177 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
178 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
179 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
180 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
181 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL5RA 1件: IL5RA 💬 |
D09874 D09874 💬 |
Benralizumab | 044 5件: 44, 45, 98, 162, 299 💬 |
182 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
183 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
184 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
185 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
186 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
187 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
188 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
189 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
190 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
191 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
192 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
193 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 2件: 113, 299 💬 |
194 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
195 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 |
196 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
197 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
198 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
199 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CXCR1 2件: CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 2件: 298, 299 💬 |
200 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
201 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
202 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
CXCR1 2件: CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 2件: 298, 299 💬 |
203 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
204 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
205 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR 1件: PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 4件: 13, 46, 49, 299 💬 |
206 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR 1件: PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 1件: 299 💬 |
207 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
208 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA 1件: RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
209 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
210 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
211 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
212 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
213 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
214 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
215 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
216 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
217 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
218 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
219 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
220 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
221 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
222 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
223 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
224 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
225 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
226 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
227 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
228 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
229 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
230 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
231 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
232 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB 1件: RARB 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
233 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
234 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
235 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
236 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
237 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
238 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
239 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
240 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
241 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
242 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
KCNJ11 1件: KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
243 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
244 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D05066 D05066 💬 |
Molgramostim | 097 3件: 97, 229, 299 💬 |
245 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
246 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL5RA 1件: IL5RA 💬 |
D09874 D09874 💬 |
Benralizumab | 044 5件: 44, 45, 98, 162, 299 💬 |
247 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
248 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
249 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
250 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
251 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
252 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
253 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
CXCR2 1件: CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 2件: 298, 299 💬 |
254 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
255 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
256 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
257 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
258 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
259 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
260 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
261 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
262 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
263 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
264 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
265 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
266 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
267 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
268 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
269 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
270 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
271 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
272 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
273 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
274 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
275 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
276 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
277 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
278 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
279 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
280 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
281 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
282 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
283 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
284 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
285 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
286 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D09889 D09889 💬 |
Dulaglutide | 013 2件: 13, 299 💬 |
287 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
288 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
289 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
290 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
291 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
292 | Intestinal immune network for IgA production 💬 Related to 16 target genes, 27 drugs (DrugBank) and 47 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
293 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D05066 D05066 💬 |
Molgramostim | 097 3件: 97, 229, 299 💬 |
294 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
295 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
296 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL5RA 1件: IL5RA 💬 |
D09874 D09874 💬 |
Benralizumab | 044 5件: 44, 45, 98, 162, 299 💬 |
297 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
IFNGR1 1件: IFNGR1 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
298 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
299 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
300 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
301 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
302 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
303 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
304 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
305 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
306 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
307 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
308 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
309 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
310 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
311 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
312 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
313 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
314 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
315 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
316 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
317 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
318 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
319 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
320 | Lysosome 💬 Related to 14 target genes, 24 drugs (DrugBank) and 6 diseases in DDrare |
CTSC 1件: CTSC 💬 |
D12120 D12120 💬 |
Brensocatib | 299 1件: 299 💬 |
321 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
322 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
323 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
324 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
325 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
326 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
327 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
328 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
329 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
330 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
331 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
332 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
333 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
334 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
335 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
336 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
337 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
338 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
339 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
340 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
341 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
342 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 3件: 13, 86, 299 💬 |
343 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
344 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D05032 D05032 💬 |
Miglustat | 019 3件: 19, 256, 299 💬 |
345 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
346 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
347 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
CLCN2 1件: CLCN2 💬 |
D04790 D04790 💬 |
Lubiprostone | 006 4件: 6 , 13, 290, 299 💬 |
348 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR 1件: VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 2件: 113, 299 💬 |
349 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
350 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR 1件: VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 |
351 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
352 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
353 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
354 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
355 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
356 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
357 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
358 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
359 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
360 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
361 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
362 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
363 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
364 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
365 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
366 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
367 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
368 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
369 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
370 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AVPR1A 3件: AVPR1A, AVPR1B, AVPR2 💬 |
D06672 D06672 💬 |
Terlipressin | 299 1件: 299 💬 |
371 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
372 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CHRM2 2件: CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
373 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CNR2 1件: CNR2 💬 |
D11312 D11312 💬 |
Ajulemic acid | 050 3件: 50, 51, 299 💬 |
374 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
375 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
376 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
377 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D09889 D09889 💬 |
Dulaglutide | 013 2件: 13, 299 💬 |
378 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00246 D00246 💬 |
Budesonide | 066 9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 💬 |
379 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00292 D00292 💬 |
Dexamethasone | 013 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
380 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D07981 D07981 💬 |
Fluticasone | 098 3件: 98, 228, 299 💬 |
381 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00088 D00088 💬 |
Hydrocortisone | 006 10件: 6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬 |
382 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
383 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 |
384 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
385 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
PTGFR 1件: PTGFR 💬 |
D06274 D06274 💬 |
Tafluprost | 299 1件: 299 💬 |
386 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
387 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
388 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
389 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
390 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
391 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
392 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
393 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
394 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
RARB 1件: RARB 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
395 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 13 diseases in DDrare |
PDE1A 4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
396 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 13 diseases in DDrare |
PDE1A 4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
397 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
398 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PGR 1件: PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 4件: 13, 46, 49, 299 💬 |
399 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PGR 1件: PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 1件: 299 💬 |
400 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
401 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
402 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
403 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
404 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
405 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
406 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
407 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
408 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
409 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
410 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
411 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
412 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
413 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
414 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
415 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
416 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
417 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
418 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
419 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
420 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
421 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
422 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
423 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
424 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
425 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
426 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
427 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
428 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
429 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
430 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
431 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
432 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
433 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
434 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR 1件: VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 2件: 113, 299 💬 |
435 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
436 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR 1件: VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 |
437 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
438 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
439 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
440 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D05066 D05066 💬 |
Molgramostim | 097 3件: 97, 229, 299 💬 |
441 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
442 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
443 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
444 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
445 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
446 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL5RA 1件: IL5RA 💬 |
D09874 D09874 💬 |
Benralizumab | 044 5件: 44, 45, 98, 162, 299 💬 |
447 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
448 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
449 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
RARA 2件: RARA, RARB 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
450 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
451 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
452 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
453 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
454 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
455 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
456 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
457 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
458 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
459 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AVPR1A 3件: AVPR1A, AVPR1B, AVPR2 💬 |
D06672 D06672 💬 |
Terlipressin | 299 1件: 299 💬 |
460 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
CXCR1 2件: CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 2件: 298, 299 💬 |
461 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
462 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
463 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
464 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
PTGFR 1件: PTGFR 💬 |
D06274 D06274 💬 |
Tafluprost | 299 1件: 299 💬 |
465 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
466 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CHRM2 1件: CHRM2 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
467 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
GHR 2件: GHR, IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
468 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
469 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
470 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
471 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
472 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 1件: PTGS1 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
473 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
474 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
475 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
476 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
477 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
478 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
479 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PGR 1件: PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 4件: 13, 46, 49, 299 💬 |
480 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PGR 1件: PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 1件: 299 💬 |
481 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
482 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
483 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
484 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
485 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
486 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
487 | Protein digestion and absorption 💬 Related to 7 target genes, 7 drugs (DrugBank) and 13 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
488 | Protein digestion and absorption 💬 Related to 7 target genes, 7 drugs (DrugBank) and 13 diseases in DDrare |
DPP4 1件: DPP4 💬 |
D08996 D08996 💬 |
Saxagliptin | 299 1件: 299 💬 |
489 | Protein digestion and absorption 💬 Related to 7 target genes, 7 drugs (DrugBank) and 13 diseases in DDrare |
DPP4 1件: DPP4 💬 |
D08516 D08516 💬 |
Sitagliptin | 006 4件: 6 , 75, 233, 299 💬 |
490 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
491 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
492 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
493 | Proximal tubule bicarbonate reclamation 💬 Related to 6 target genes, 6 drugs (DrugBank) and 19 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
494 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
495 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
496 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
497 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
498 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
499 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 3件: 13, 86, 299 💬 |
500 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
501 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
502 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
503 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
504 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
505 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
506 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
507 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
508 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
509 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
510 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM2 2件: CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
511 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
512 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
513 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
514 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
515 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
516 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
517 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
518 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
519 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
520 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
521 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
522 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
523 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
524 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
525 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
526 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
527 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
528 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
529 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
530 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
531 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
532 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |
533 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 3件: 85, 228, 299 💬 |
534 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
535 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 1件: 299 💬 |
536 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
537 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
538 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
539 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
540 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
541 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
542 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D07448 D07448 💬 |
Amitriptyline | 078 4件: 78, 97, 226, 299 💬 |
543 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
544 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
545 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
546 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
RARB 1件: RARB 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
547 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D05032 D05032 💬 |
Miglustat | 019 3件: 19, 256, 299 💬 |
548 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
549 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
550 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
551 | Staphylococcus aureus infection 💬 Related to 12 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
552 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 2件: SLC6A2, SLC6A4 💬 |
D07448 D07448 💬 |
Amitriptyline | 078 4件: 78, 97, 226, 299 💬 |
553 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
554 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
555 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
556 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
557 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
558 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
PDE1A 3件: PDE1A, PDE1B, PDE1C 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
559 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
PDE1A 3件: PDE1A, PDE1B, PDE1C 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
560 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
SCNN1A 3件: SCNN1A, SCNN1B, SCNN1G 💬 |
D07447 D07447 💬 |
Amiloride | 013 4件: 13, 67, 225, 299 💬 |
561 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
562 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
563 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
564 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
565 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
566 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
567 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
568 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
569 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
570 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
571 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
572 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
573 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
574 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
RARA 1件: RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
575 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
576 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
577 | Thyroid cancer 💬 Related to 8 target genes, 16 drugs (DrugBank) and 28 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
578 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
579 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
580 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
581 | Thyroid hormone synthesis 💬 Related to 7 target genes, 6 drugs (DrugBank) and 7 diseases in DDrare |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 1件: 299 💬 |
582 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
583 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
584 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
585 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
586 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
587 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
588 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
589 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
590 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
591 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
592 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
593 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
594 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 1件: RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
595 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
596 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
597 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
598 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR 1件: VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 2件: 113, 299 💬 |
599 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
600 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR 1件: VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 |
601 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
602 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
603 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
604 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
605 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
606 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
607 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AVPR1A 2件: AVPR1A, AVPR1B 💬 |
D06672 D06672 💬 |
Terlipressin | 299 1件: 299 💬 |
608 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
609 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 1件: AVPR2 💬 |
D06672 D06672 💬 |
Terlipressin | 299 1件: 299 💬 |
610 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
611 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
612 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
613 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 1件: 299 💬 |
614 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 1件: 299 💬 |
615 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 1件: 299 💬 |
616 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 1件: 299 💬 |
617 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 1件: 299 💬 |
618 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR 1件: CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 1件: 299 💬 |
619 | Viral life cycle - HIV-1 💬 Related to 4 target genes, 5 drugs (DrugBank) and 9 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
620 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CXCR1 2件: CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 2件: 298, 299 💬 |
621 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
622 | Virion - Human immunodeficiency virus 💬 Related to 3 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
623 | Wnt signaling pathway 💬 Related to 9 target genes, 9 drugs (DrugBank) and 61 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
624 | Wnt signaling pathway 💬 Related to 9 target genes, 9 drugs (DrugBank) and 61 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |