299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details

臨床試験数 : 1,695 / 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

14 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2009-012575-10-SE (EUCTR)	08/12/2016	04/10/2016	Trial of Optimal Therapy for Pseudomonas Eradication in Cystic Fibrosis - TORPEDO-CF	Trial of Optimal Therapy for Pseudomonas Eradication in Cystic Fibrosis - TORPEDO-CF		Product Name: Ceftazidime INN or Proposed INN: Ceftazidime Other descriptive name: N/A Product Name: To ...	University Hospitals Bristol NHS Foundation Trust	University of Liverpool	Not Recruiting			Female: yes Male: yes	260	Phase 4	United Kingdom;Sweden
2	EUCTR2016-001785-29-IE (EUCTR)	15/08/2016	10/05/2016	Study of the effects of combined treatment with the CFTR corrector ivacaftor and IV antibiotics on i ...	Combined Effect of CFTR Modifiers and Intensive Antibiotic Treatment	Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]	Trade Name: Kalydeco INN or Proposed INN: IVACAFTOR Trade Name: Ciprofloxacin INN or Proposed INN: Cipr ...	St. Vincent's University Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 4	Ireland
3	EUCTR2016-000398-19-BE (EUCTR)	08/03/2016	09/02/2016	Pilot study: pharmacokinetics of beta-lactam antibiotics, piperacillin-tazobactam, ceftazidimand mer ...	Pilot study: pharmacokinetics of beta-lactam antibiotics, piperacillin-tazobactam, ceftazidimand mer ...	Cystic fibrosis;Therapeutic area: Diseases [C] - Bacterial Infections and Mycoses [C01]	Trade Name: Meropenem Fresenius Kabi 1 g poeder voor oplossing voor injectie of infusie INN or Proposed ...	Ghent University	NULL	Not Recruiting			Female: yes Male: yes	45	Phase 4	Belgium
4	NCT02840136 (ClinicalTrials.gov)	February 2016	18/7/2016	LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputum of Cysti ...	Optimisation, Valorisation and Application of UPLC-MS/MS Based Monitoring of Antibiotic Concentratio ...	Cystic Fibrosis	Drug: Piperacillin -tazobactam combination product;Drug: Meropenem;Drug: Ceftazidime	University Ghent	King Baudouin Foundation;Belgische Vereniging voor Strijd tegen Mucoviscidose	Suspended	12 Years	N/A	All	40	N/A	Belgium
5	NCT02504827 (ClinicalTrials.gov)	September 2015	20/7/2015	Steady-state Pharmacokinetics of Ceftazidime/Avibactam in Cystic Fibrosis	Steady-state Pharmacokinetics of Ceftazidime/Avibactam in CF	Cystic Fibrosis	Drug: Ceftazidime /avibactam	University of Southern California	NULL	Completed	18 Years	N/A	All	12	Phase 4	United States
6	NCT02526004 (ClinicalTrials.gov)	October 1, 2013	10/8/2015	Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified	Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified	Cystic Fibrosis	Drug: Ceftazidime;Drug: Tobramycin	University College Cork	Queen's University, Belfast;University of Paris 5 - Rene Descartes;University of Dundee;University o ...	Completed	16 Years	80 Years	All	223	N/A	Ireland
7	NCT01667094 (ClinicalTrials.gov)	September 2012	13/8/2012	A Study Comparing Continuous Infusion Antibiotics to Standard Treatment for Lung Infections in Cysti ...	Continuous-infusion Anti-pseudomonal ß-lactams for the Treatment of Acute, Infective Pulmonary Exace ...	Cystic Fibrosis	Drug: Intermittent, short infusion Ceftazidime;Drug: Continuous infusion Ceftazidime;Drug: Intermitt ...	The Alfred	NULL	Active, not recruiting	18 Years	N/A	All	50	Phase 4	Australia
8	NCT01044719 (ClinicalTrials.gov)	January 2010	14/12/2009	Duration of Antibiotics in Infective Exacerbations of Cystic Fibrosis	What Duration of Intravenous Antibiotic Therapy Should be Used in the Treatment of Infective Exacerb ...	Cystic Fibrosis	Drug: Ceftazidime;Drug: Tobramycin;Drug: Meropenem	Imperial College London	NULL	Not yet recruiting	16 Years	N/A	Both	240	Phase 4	United Kingdom
9	EUCTR2009-012575-10-GB (EUCTR)	16/11/2009	11/09/2009	Trial of Optimal Therapy for Pseudomonas Eradication in Cystic Fibrosis - TORPEDO-CF	Trial of Optimal Therapy for Pseudomonas Eradication in Cystic Fibrosis - TORPEDO-CF		Product Name: Ceftazidime INN or Proposed INN: Ceftazidime Other descriptive name: N/A Product Name: To ...	University Hospitals Bristol NHS Foundation Trust	University of Liverpool	Not Recruiting			Female: yes Male: yes	260	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United Kingdom;Sweden
10	EUCTR2009-014042-28-GB (EUCTR)	16/10/2009	14/10/2010	What duration of intravenous antibiotic therapy should be used in the treatment of infective exacerb ...	What duration of intravenous antibiotic therapy should be used in the treatment of infective exacerb ...	Cystic Fibrosis	Trade Name: Meropenem Product Name: Meropenem INN or Proposed INN: Meropenem Trade Name: Ceftazidime Pro ...	Imperial College, London	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	240		United Kingdom

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