299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

  
6 trials found
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1NCT05663255
(ClinicalTrials.gov)
March 1, 202315/12/2022Effectiveness of CFTR Modulators According to Co-therapyIs Effectiveness of CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Modulators Impacted by Co-therapy? A Population-based Comparative Effectiveness Study Using Data From French Cystic Fibrosis Registry Linked to French National Healthcare Insurance DatabaseCystic FibrosisDrug: Discontinuation of respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)Hospices Civils de LyonNULLNot yet recruiting6 YearsN/AAll1990NULL
2NCT05581056
(ClinicalTrials.gov)
February 24, 202312/10/2022Evaluation of the Evolution of Quality of Life in Relation to Naso-sinus Symptomatology Under Treatment With CFTE Modulators in Children Aged 6 to 11 Years With Cystic Fibrosis With Compatible MutationEvaluation of the Evolution of Quality of Life in Relation to Naso-sinus Symptomatology Under Treatment With CFTR Modulators in Children Aged 6 to 11 Years With Cystic Fibrosis With Compatible MutationCystic FibrosisDrug: CFTR modulatorsHospices Civils de LyonNULLNot yet recruiting6 Years11 YearsAll90France
3NCT04580368
(ClinicalTrials.gov)
May 1, 20212/10/2020Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 TrialsTesting Drug Efficacy in Cystic Fibrosis Through N-of-1 TrialsCystic FibrosisDrug: CFTR ModulatorsChildren's Hospital Medical Center, CincinnatiNULLRecruiting6 YearsN/AAll50N/AUnited States
4NCT04301856
(ClinicalTrials.gov)
January 1, 202021/2/2020Response to CFTR Modulators in CF Patients Under 18 YearsEvaluation of the Response to CFTR Modulators in Patients With Cystic Fibrosis Less Than 18 Years of AgeCystic Fibrosis in ChildrenDrug: CFTR ModulatorsSociete Francaise de la MucoviscidoseNULLRecruitingN/A18 YearsAll600France
5NCT04206436
(ClinicalTrials.gov)
December 18, 201918/12/2019CFTR Modulator Effects on Bone and Muscle in Adults With Cystic FibrosisCFTR Modulator Effects on Bone and Muscle in Adults With Cystic FibrosisCystic Fibrosis;Bone Loss;Muscle LossDrug: Cftr ModulatorsIndiana UniversityCystic Fibrosis FoundationEnrolling by invitation18 YearsN/AAll60United States
6NCT03506061
(ClinicalTrials.gov)
September 4, 201913/4/2018Trikafta in Cystic Fibrosis PatientsiPS Cell Response to CFTR Modulators: Study of Trikafta in CF Patients Carrying Partial Function MutationsCystic FibrosisDrug: TrikaftaEmory UniversityNational Heart, Lung, and Blood Institute (NHLBI)Recruiting12 YearsN/AAll22Phase 2United States