299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

  
5 trials found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
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Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
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PhaseCountries
1EUCTR2019-003501-10-NO
(EUCTR)
08/03/202129/05/2020Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a phase 4 multicenter randomized controlled study.Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a phase 4 multicenter randomized controlled study. - MBWtodetectPEXinCF Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]Trade Name: Amoxicillin
Product Name: Amoxicillin
INN or Proposed INN: AMOXICILLIN
Trade Name: Amoxicillin and Clavulanic acid
Product Name: Augmentin
INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: CLAVULANIC ACID
Trade Name: Heracillin
Product Name: Heracillin
INN or Proposed INN: FLUCLOXACILLIN
Trade Name: Dicloxacillin
Product Name: Dicloxacillin
INN or Proposed INN: DICLOXACILLIN
Trade Name: Trimethoprim and Sulfamethoxazole
Product Name: Bactrim
INN or Proposed INN: Trimetoprim
Other descriptive name: TRIMETHOPRIM
INN or Proposed INN: SULFAMETHOXAZOLE
Trade Name: Clarithromycin
Product Name: Klacid
INN or Proposed INN: Klacid
Other descriptive name: CLARITHROMYCIN
Trade Name: Rifampicin
Product Name: Rimactan
INN or Proposed INN: RIFAMPICIN
Trade Name: Doxycycline
Product Name: Doxycyclin
INN or Proposed INN: DOXYCYCLINE
Product Name: Fucidin Tablets
INN or Proposed INN: Fusidin
Other descriptive name: FUSIDIC ACID
Trade Name: Ciprofloxacin
Product Name: Ciprofloxacin
INN or Proposed INN: Ciproxin
Other descriptive name: CIPROFLOXACIN
Trade Name: Linez
Vãstre Gõtalandsregionen, SwedenNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
100Phase 4Denmark;Norway;Sweden
2EUCTR2019-003501-10-DK
(EUCTR)
22/01/202122/04/2020Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study.Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study. - MBWtodetectPEXinCF Cystic fibrosis
MedDRA version: 22.1;Level: LLT;Classification code 10068288;Term: Cystic fibrosis pulmonary exacerbation;System Organ Class: 100000004862;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: CLAVULANIC ACID
INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: FLUCLOXACILLIN
INN or Proposed INN: DICLOXACILLIN
INN or Proposed INN: SULFAMETHOXAZOLE
INN or Proposed INN: Trimetoprim
Other descriptive name: TRIMETHOPRIM
INN or Proposed INN: Clarithromycin
Other descriptive name: CLARITHROMYCIN
INN or Proposed INN: RIFAMPICIN
INN or Proposed INN: DOXYCYCLINE
INN or Proposed INN: Fusidic acid
Other descriptive name: FUSIDIC ACID
INN or Proposed INN: Ciprofloxacin
Other descriptive name: CIPROFLOXACIN
INN or Proposed INN: Linezolid
Other descriptive name: LINEZOLID
INN or Proposed INN: CLINDAMYCIN
Other descriptive name: CLINDAMYCIN
INN or Proposed INN: Cefuroxim
Other descriptive name: CEFUROXIME
INN or Proposed INN: CEFALEXIN
Västra GötalandsregionenNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
100Phase 4Denmark;Norway;Sweden
3EUCTR2019-003501-10-SE
(EUCTR)
08/04/202007/04/2020Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study.Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study. - MBWtodetectPEXinCF Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: CLAVULANIC ACID
INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: FLUCLOXACILLIN
INN or Proposed INN: DICLOXACILLIN
INN or Proposed INN: SULFAMETHOXAZOLE
INN or Proposed INN: Trimetoprim
Other descriptive name: TRIMETHOPRIM
INN or Proposed INN: Clarithromycin
Other descriptive name: CLARITHROMYCIN
INN or Proposed INN: RIFAMPICIN
INN or Proposed INN: DOXYCYCLINE
INN or Proposed INN: Fusidic acid
Other descriptive name: FUSIDIC ACID
INN or Proposed INN: Ciprofloxacin
Other descriptive name: CIPROFLOXACIN
INN or Proposed INN: Linezolid
Other descriptive name: LINEZOLID
INN or Proposed INN: CLINDAMYCIN
Other descriptive name: CLINDAMYCIN
INN or Proposed INN: Cefuroxim
Other descriptive name: CEFUROXIME
INN or Proposed INN: CEFALEXIN
Västra GötalandsregionenNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
100Phase 4Denmark;Norway;Sweden
4EUCTR2016-002578-11-GB
(EUCTR)
16/09/201609/08/2016A trial to determine the safest and most effective antibiotic strategy for infants diagnosed with CF.The cystic fibrosis (CF) anti-staphylococcal antibiotic prophylaxis trial (CF START); a randomised registry trial to assess the safety and efficacy of flucloxacillin as a longterm prophylaxis agent for infants with CF. - CF START Cystic fibrosis
MedDRA version: 19.0;Level: PT;Classification code 10011762;Term: Cystic fibrosis;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Trade Name: Flucloxacillin 250mg/5ml Sugar-Free Powder for Oral Solution
Product Name: Flucloxacillin
Product Code: na
INN or Proposed INN: Flucloxacillin
Alder Hey Children's NHS Foundation TrustNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
480Phase 4United Kingdom
5EUCTR2016-001785-29-IE
(EUCTR)
15/08/201610/05/2016Study of the effects of combined treatment with the CFTR corrector ivacaftor and IV antibiotics on infection in CF.Combined Effect of CFTR Modifiers and Intensive Antibiotic Treatment Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]Trade Name: Kalydeco
INN or Proposed INN: IVACAFTOR
Trade Name: Ciprofloxacin
INN or Proposed INN: Ciprofloxacin
Other descriptive name: CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATE
Product Name: Flucloxicillin
INN or Proposed INN: FLUCLOXACILLIN SODIUM
Trade Name: Fortum
INN or Proposed INN: CEFTAZIDIME
Product Name: Tobramycin
INN or Proposed INN: TOBRAMYCIN SULFATE
Trade Name: Meropenem
INN or Proposed INN: Meropenem
Other descriptive name: MEROPENEM
Trade Name: Colistin
INN or Proposed INN: COLISTIMETHATE SODIUM
St. Vincent's University HospitalNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Phase 4Ireland