DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
299. 嚢胞性線維症
Cystic fibrosis
Clinical trials
/
Disease details
臨床試験数
:
1,695
/
薬物数
:
1,527
- (
DrugBank
:
268
) /
標的遺伝子数
:
111
-
標的パスウェイ数
:
174
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Phase
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1
NCT01975259
(
ClinicalTrials.gov
)
December 2013
11/9/2013
Investigating the Incretin Effect in Cystic Fibrosis
Investigating the Incretin Effect in Cystic Fibrosis
Cystic Fibrosis
Drug:
Oral Glucose Tolerance test (75g 2-hour)
;Drug:
Modified Oral Glucose Tolerance Test (50g 4-hours)
;Drug:
Matched isoglycemic clamp
;Drug:
Hyperglycemic clamp
with concurrent GLP-1 infusion
;Drug:
Hyperglycemic Clamp
with concurrent GIP infusion
;Drug:
Hyperglycemic clamp
with placebo infusion;Other: Liquid Meal Test (Carbohydrate-rich);Other: Liquid Meal Test (Fat-rich);Other: Liquid Meal Test (Mixed);Device: Continuous
Glucose
Monitoring
Drug:
Oral Glucose Tolerance test (75g 2-hour)
;Drug:
Modified Oral Glucose Tolerance Test (50g 4-hou
...
Liverpool Heart and Chest Hospital NHS Foundation Trust
NULL
Completed
17 Years
50 Years
Both
50
N/A
United Kingdom