299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

  
4 trials found
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PhaseCountries
1EUCTR2012-002880-86-GB
(EUCTR)
25/01/201309/11/2012Resting the pancreas in Cystic FibrosisPRESERVING ?ETA-CELLS: ‘RESTING THE PANCREAS’ IN CYSTIC FIBROSIS Cystic Fibrosis Related Diabetes (CFRD)
MedDRA version: 14.1;Level: LLT;Classification code 10022468;Term: Insulin;System Organ Class: 100000004848;Therapeutic area: Body processes [G] - Physiological processes [G07]
Trade Name: Levemir FlexPen
Product Name: Levemir FlexPen
Liverpool Heart and Chest Hospital NHS TrustNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
United Kingdom
2EUCTR2007-004956-35-GB
(EUCTR)
27/08/200826/11/2007The effect of intensive blood glucose control with insulin on markers of short and medium term outcomes in patients hospitalised with acute exacerbations of chronic lung disease. Pilot Study to test feasibility and safety of a clinical protocol for intensive blood glucose control with insulin on medical wards - Pilot of Intensive Blood Glucose Control with Insulin on Medical WardsThe effect of intensive blood glucose control with insulin on markers of short and medium term outcomes in patients hospitalised with acute exacerbations of chronic lung disease. Pilot Study to test feasibility and safety of a clinical protocol for intensive blood glucose control with insulin on medical wards - Pilot of Intensive Blood Glucose Control with Insulin on Medical Wards Acute exacerbations of chronic obstructive pulmonary disease. Stress hyperglycaemia. Insulin-induced hypoglycaemia. Cystic fibrosis
MedDRA version: 9.1;Level: LLT;Classification code 10010953;Term: COPD exacerbation
MedDRA version: 9.1;Classification code 10060439;Term: Stress induced hyperglycaemia
MedDRA version: 9.1;Classification code 10022484;Term: Insulin hypoglycaemia
MedDRA version: 9.1;Classification code 10011762;Term: Cystic fibrosis
Trade Name: Actrapid 100 IU/ml, Solution for injection in a vial
Trade Name: Levemir 100 U/ml solution for injection in a cartridge, Levemir 100 U/ml solution for injection in a pre-filled pen
Trade Name: NovoRapid 100 U/ml, solution for injection in a vial. NovoRapid Penfill 100 U/ml, solution for injection in a cartridge. NovoRapid FlexPen 100 U/ml, solution for injection in a pre-filled pen.
Trade Name: Lantus® 100 Units/ml solution for injection in a vial. Lantus® 100 Units/ml solution for injection in a cartridge. Lantus® 100 Units/ml solution for injection in a pre-filled pen
St George's, University of LondonNULLNot RecruitingFemale: yes
Male: yes
United Kingdom
3NCT00639626
(ClinicalTrials.gov)
August 200814/3/2008Use of Levemir® Improves Metabolic and Clinical Status in Cystic Fibrosis-related Diabetes (CFRD)Use of Levemir® Improves Metabolic and Clinical Status in CFRDCystic Fibrosis Related DiabetesDrug: insulin detemir [rDNA origin] injectionNationwide Children's HospitalNovo Nordisk A/STerminated16 Years45 YearsAll6Phase 2/Phase 3United States
4EUCTR2005-002997-31-GB
(EUCTR)
10/08/200609/11/2005A multi-centre randomised trial of insulin detemir in pre-diabetes associated with cystic fibrosis. - Randomized trial of insulin detemir in CF associated pre-diabetesA multi-centre randomised trial of insulin detemir in pre-diabetes associated with cystic fibrosis. - Randomized trial of insulin detemir in CF associated pre-diabetes Individuals with cystic fibrosis develop diabetes. They exhibit abnormal glucose handling (impaired glucose tolerance), poor growth and a decline in lung function before overt diabetes develops. Early treatment with insulin before diabetes develops may improve weight gain and lung function and delay progression to overt diabetes.Product Name: Levemir PenfillSheffield Children's NHS TrustNULLNot Recruiting Female: yes
Male: yes
40 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): yesUnited Kingdom