299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details
臨床試験数 : 1,695 / 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05530278 (ClinicalTrials.gov) | September 20, 2022 | 5/9/2022 | A Study to Assess the Pharmacokinetics and Safety of Co-administered Oral Galicaftor, Navocaftor, and ABBV-576 in Healthy Adults for the Treatment of Cystic Fibrosis | Assessment of Multiple-Dose Pharmacokinetics and Safety of the Co-administration of Galicaftor, Navocaftor and ABBV-576 and Potential of ABBV-576 for CYP3A Induction in Healthy Volunteers | Healthy Volunteers | Drug: Galicaftor;Drug: ABBV-576;Drug: Navocaftor;Drug: Midazolam | AbbVie | NULL | Completed | 18 Years | 65 Years | Female | 24 | Phase 1 | United States |
| 2 | NCT01060566 (ClinicalTrials.gov) | February 2010 | 29/1/2010 | Study of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770 | An Open-Label Phase 1 Study to Examine the Effect of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770 in Healthy Subjects | Cystic Fibrosis | Drug: VX-770 | Vertex Pharmaceuticals Incorporated | NULL | Completed | 18 Years | 55 Years | Both | 24 | Phase 1 | United States |