41. 巨細胞性動脈炎 Giant cell arteritis Clinical trials / Disease details

臨床試験数 : 131 / 薬物数 : 139 - (DrugBank : 36) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 125

30 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05623592 (ClinicalTrials.gov)	November 23, 2022	8/11/2022	Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumaband Glucocor ...	A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy of Met ...	Giant Cell Arteritis	Drug: Methotrexate;Drug: Sodium chloride	University of Bonn	NULL	Recruiting	18 Years	N/A	All	40	Phase 2	Germany
2	NCT05168475 (ClinicalTrials.gov)	July 14, 2021	9/12/2021	Biologics in Refractory Vasculitis	Biologics in Refractory Vasculitis (BIOVAS): A Pragmatic, Randomised, Double-blind, Placebo-controll ...	Giant Cell Arteritis;Takayasu Arteritis;Cogan Syndrome;Relapsing Polychondritis;Cryoglobulinemic Vas ...	Biological: Rituximab;Biological: Infliximab;Biological: Tocilizumab	Cambridge University Hospitals NHS Foundation Trust	NULL	Recruiting	5 Years	N/A	All	140	Phase 2	United Kingdom
3	NCT04885829 (ClinicalTrials.gov)	May 31, 2021	3/5/2021	Comparative Study of 3 Tocilizumab Products in Normal Healthy Volunteeers	A Single Dose, Double-Blind, Two-Period, Crossover, Comparative Pharmacokinetic Study of Three Tocil ...	Rheumatoid Arthritis;Giant Cell Arteritis	Drug: Tocilizumab Prefilled Syringe	Syneos Health	Dr. Reddy's Laboratories Limited	Active, not recruiting	18 Years	50 Years	All	300	Phase 1	Australia;India;New Zealand
4	NCT04888221 (ClinicalTrials.gov)	May 2021	25/3/2021	Efficacy of Tocilizumabin Association to Steroids in Giant Cell Arteritis With Cerebro-vascular Invo ...	Efficacy of Tocilizumabin Association to Steroids in Giant Cell Arteritis With Cerebro-vascular Invo ...	Giant Cell Arteritis;Neurovascular Disorder	Drug: Tocilizumab;Drug: Placebo	Assistance Publique - Hôpitaux de Paris	Roche Chugai;Roche Pharma AG	Not yet recruiting	60 Years	N/A	All	66	Phase 3	France
5	EUCTR2019-003964-30-GB (EUCTR)	22/10/2020	31/07/2020	Biologics in refractory vasculitis (BIOVAS): A pragmatic, randomised, double-blind, placebo-controll ...	Biologics in refractory vasculitis (BIOVAS): A pragmatic, randomised, double-blind, placebo-controll ...	Non-ANCA associated vasculitides: 1.Giant cell arteritis (GCA)2.Takayasu’s arteritis (TA)3.Polyarter ...	Product Name: Infliximab Product Code: N/A INN or Proposed INN: Infliximab Trade Name: Rituximab Product ...	Cambridge University Hospitals NHS Foundation Trust	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 2	United Kingdom
6	NCT04239196 (ClinicalTrials.gov)	July 1, 2020	19/11/2019	Efficacy of Tocilizumab for the Treatment of Acute AION Related to GCA	Open Label Phase II Randomized Non-comparative Study of SC TocilizumabAssociated With IV Pulse Stero ...	Giant Cell Arteritis;Optic Ischaemic Neuropathy	Drug: tocilizumab and IV steroids combination;Other: IV steroids combination alone	Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts	Roche Chugai	Not yet recruiting	50 Years	N/A	All	58	Phase 2	France
7	NCT05394909 (ClinicalTrials.gov)	February 7, 2020	20/5/2022	Ultra-short Glucocorticosteroids and Tocilizumab Therapy in GCA Patients	Treatment Of Giant Cell Arteritis Patients With Ultra-short Glucocorticosteroids And tociliZumab: Ro ...	GCA;TOCILIZUMAB;Glucocorticoids;PET	Drug: Tocilizumab 162Mg/0.9Ml Autoinjector	Azienda Unità Sanitaria Locale Reggio Emilia	NULL	Active, not recruiting	N/A	N/A	All	20		Italy
8	NCT03892785 (ClinicalTrials.gov)	January 27, 2020	26/3/2019	MEthotrexate Versus TOcilizumabfor Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Con ...	MEthotrexate Versus TOcilizumabfor Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Con ...	Giant Cell Arteritis	Drug: Prednisone treatment;Drug: Tocilizumab treatment;Drug: Methotrexate treatment;Other: Questionnair ...	Centre Hospitalier Universitaire Dijon	NULL	Recruiting	50 Years	N/A	All	230	Phase 3	France
9	NCT03923738 (ClinicalTrials.gov)	August 5, 2019	19/4/2019	A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab(TCZ) Administe ...	A Phase Ib, Open-Label, Dose-Ranging Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and S ...	Giant Cell Arteritis	Drug: Tocilizumab	Hoffmann-La Roche	NULL	Completed	50 Years	N/A	All	23	Phase 1	Switzerland
10	EUCTR2018-002826-22-FR (EUCTR)	07/03/2019	21/11/2018	MEthotrexate versus TOcilizumabfor treatment of GIant cell Arteritis: a multicenter, randomized, con ...	MEthotrexate versus TOcilizumabfor treatment of GIant cell Arteritis: a multicenter, randomized, con ...	MedDRA version: 20.0;Level: LLT;Classification code 10018250;Term: Giant cell arteritis;System Orga ...	Trade Name: METOJECT Trade Name: RoActemra	CHU Dijon Bourgogne	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: no	200	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	France

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