DDrare
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No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CSF2RA
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
4件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
D09930
D09930
Mavrilimumab
2件:
41
41
,
46
2
CSF3R
5件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
5件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
, ...
D03235
D03235
Filgrastim
35件:
2
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
65
,
85
,
96
,
113
,
164
,
256
,
283
,
284
,
285
,
296
,
331
35件:
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
6
...
3
DHFR
5件:
One carbon pool by folate
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
Antifolate resistance
5件:
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
A
...
D00142
D00142
Methotrexate
38件:
11
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
,
97
,
107
,
162
,
164
,
172
,
256
,
270
,
271
,
283
,
284
,
285
,
286
,
326
,
331
38件:
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
, ...
4
EDNRA
7件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Vascular smooth muscle contraction
,
Renin secretion
,
Pathways in cancer
7件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligan
...
D01227
D01227
Bosentan
10件:
41
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
5
EDNRA
7件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Vascular smooth muscle contraction
,
Renin secretion
,
Pathways in cancer
7件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligan
...
D07538
D07538
Bosentan
10件:
41
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
6
EDNRB
6件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Melanogenesis
,
Relaxin signaling pathway
,
Pathways in cancer
6件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
D01227
D01227
Bosentan
10件:
41
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
7
EDNRB
6件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Melanogenesis
,
Relaxin signaling pathway
,
Pathways in cancer
6件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
D07538
D07538
Bosentan
10件:
41
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
8
DHFR2
5件:
One carbon pool by folate
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
Antifolate resistance
5件:
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
A
...
D00142
D00142
Methotrexate
38件:
11
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
,
97
,
107
,
162
,
164
,
172
,
256
,
270
,
271
,
283
,
284
,
285
,
286
,
326
,
331
38件:
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
, ...
9
FDPS
4件:
Terpenoid backbone biosynthesis
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1 infection
4件:
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
Influenza A
,
Human T-cell leukemia virus 1
...
D07119
D07119
Alendronic acid
7件:
19
19
,
41
,
46
,
50
,
271
,
274
,
299
10
NR3C1
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
D00088
D00088
Hydrocortisone
9件:
41
41
,
46
,
53
,
75
,
78
,
81
,
83
,
97
,
299