43. 顕微鏡的多発血管炎 Microscopic polyangiitis Clinical trials / Disease details

臨床試験数 : 88 / 薬物数 : 81 - (DrugBank : 21) / 標的遺伝子数 : 15 - 標的パスウェイ数 : 90

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05376319 (ClinicalTrials.gov)	March 2023	11/5/2022	PR3-AAV Resilient Remission or PRRR	A Randomized, Double-Blind, Active Comparator-Controlled Study to Evaluate the Effect of Obinutuzuma ...	Granulomatosis With Polyangiitis;Microscopic Polyangiitis;ANCA Associated Vasculitis	Drug: Obinutuzumab;Drug: Rituximab	Mayo Clinic	NULL	Not yet recruiting	18 Years	N/A	All	30	Phase 2	United States
2	NCT04316494 (ClinicalTrials.gov)	December 17, 2020	25/2/2020	Hydroxychloroquine in ANCA Vasculitis Evaluation	Hydroxychloroquine in ANCA Vasculitis Evaluation - A Multicentre, Randomised, Double-blind, Placebo- ...	ANCA Associated Vasculitis;Microscopic Polyangiitis;Churg-Strauss Syndrome;Wegener Granulomatosis	Drug: Hydroxychloroquine;Drug: Placebo	Guy's and St Thomas' NHS Foundation Trust	Medical Research Council	Recruiting	18 Years	N/A	All	76	Phase 4	United Kingdom
3	NCT03920722 (ClinicalTrials.gov)	October 24, 2020	18/2/2019	Efficacy and Safety of Rituximab in the Treatment of Good Prognosis Microscopic Polyangiitis	Efficacy and Safety of Rituximab in the Treatment of Good Prognosis Microscopic Polyangiitis	Microscopic Polyangiitis (MPA)	Drug: Rituximab;Drug: placebo	Assistance Publique - Hôpitaux de Paris	French Vasculitis Study Group	Active, not recruiting	18 Years	N/A	All	8	Phase 3	France
4	NCT04280601 (ClinicalTrials.gov)	August 1, 2020	18/2/2020	PRagmatic Analysis of Vitamin D in ANCA-Associated Vasculitis	A Local Interventional Study in a Cohort of Patients With GPA, MPAand EGPA (PART 2 of Vitamin D Stat ...	ANCA-associated Vasculitis;Granulomatosis With Polyangiitis;Microscopic Polyangiitis;Eosinophilic Gr ...	Dietary Supplement: vitamin D	Christian Pagnoux	NULL	Completed	18 Years	N/A	All	102	N/A	Canada
5	EUCTR2018-001268-40-GB (EUCTR)	23/01/2020	13/09/2019	Hydroxychloroquine in ANCA vasculitis	Hydroxychloroquine in ANCA Vasculitis Evaluation - A Multicentre, Randomised, Double-blind, Placebo- ...	The term ANCA-associated vasculitis (AAV) describes a subset of primary small vessel vasculitides ch ...	Trade Name: Plaquenil - Hydroxychloroquine 200mg Film coated tablets	Guy's and St. Thomas' NHS Foundation Trust	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	76	Phase 4	United Kingdom
6	EUCTR2018-000768-27-IE (EUCTR)	26/08/2019	20/12/2018	Efficacy and safety study of a monoclonal antibody to replace steroids for treatment of patients wit ...	A RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, ACTIVE-CONTROLLED, MULTICENTER, 2-PART PHASE II STUDY ON R ...	Active Granulomatosis with Polyangiitis (Wegener’s) (GPA) and Microscopic Polyangiitis(MPA) MedDRA v ...	Product Name: IFX-1 INN or Proposed INN: not yet available Other descriptive name: chimeric monoclonal ...	InflaRx GmbH	NULL	Not Recruiting			Female: yes Male: yes	81	Phase 2	Spain;Ireland;Russian Federation;Italy;Switzerland;United Kingdom;France;Czech Republic;Belgium;Denm ...
7	EUCTR2018-000768-27-DK (EUCTR)	05/08/2019	20/03/2019	Efficacy and safety study of a monoclonal antibody to replace steroids for treatment of patients wit ...	A RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, ACTIVE-CONTROLLED, MULTICENTER, 2-PART PHASE II STUDY ON R ...	Active Granulomatosis with Polyangiitis (Wegener’s) (GPA) and Microscopic Polyangiitis(MPA) MedDRA v ...	Product Name: IFX-1 INN or Proposed INN: not yet available Other descriptive name: chimeric monoclonal ...	InflaRx GmbH	NULL	Not Recruiting			Female: yes Male: yes	81	Phase 2	Spain;Ireland;Russian Federation;Italy;Switzerland;United Kingdom;France;Czech Republic;Belgium;Denm ...
8	EUCTR2018-000768-27-GB (EUCTR)	17/04/2019	27/12/2018	Efficacy and safety study of a monoclonal antibody to replace steroids for treatment of patients wit ...	A RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, ACTIVE-CONTROLLED, MULTICENTER, 2-PART PHASE II STUDY ON R ...	Active Granulomatosis with Polyangiitis (Wegener’s) (GPA) and Microscopic Polyangiitis(MPA) MedDRA v ...	Product Name: IFX-1 INN or Proposed INN: not yet available Other descriptive name: chimeric monoclonal ...	InflaRx GmbH	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	81	Phase 2	Spain;Ireland;Russian Federation;United Kingdom;Italy;Switzerland;France;Czech Republic;Belgium;Denm ...
9	EUCTR2018-000768-27-BE (EUCTR)	04/04/2019	01/05/2019	Efficacy and safety study of a monoclonal antibody to replace steroids for treatment of patients wit ...	A RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, ACTIVE-CONTROLLED, MULTICENTER, 2-PART PHASE II STUDY ON R ...	Active Granulomatosis with Polyangiitis (Wegener’s) (GPA) and Microscopic Polyangiitis(MPA) MedDRA v ...	Product Name: IFX-1 INN or Proposed INN: not yet available Other descriptive name: chimeric monoclonal ...	InflaRx GmbH	NULL	Not Recruiting			Female: yes Male: yes	81	Phase 2	France;Czech Republic;Spain;Belgium;Ireland;Denmark;Russian Federation;Netherlands;Germany;United Ki ...
10	NCT03895801 (ClinicalTrials.gov)	April 3, 2019	8/3/2019	Study of IFX-1 to Replace Steroids in Patients With Granulomatosis With Polyangiitis and Microscopic ...	A Randomized, Double-blind, Double-dummy, Active-controlled, Multicenter, 2-part Phase II Study on R ...	Granulomatosis With Polyangiitis (GPA);Microscopic Polyangiitis (MPA)	Drug: IFX-1;Drug: Placebo-IFX-1;Drug: Glucocorticoid (GC);Drug: Placebo-Glucocorticoid (Placebo-GC)	InflaRx GmbH	NULL	Completed	18 Years	N/A	All	57	Phase 2	Belgium;Czechia;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United ...

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