1 | 5009111000001105 | - | - | - | - | 1件: 43 43 |
2 | ALEMTUZUMAB | 1件: Alemtuzumab Alemtuzumab | 1件: D02802
D02802
| 1件: CD52 CD52 💬 | - | 17件: 13 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 |
3 | Avacopan | 1件: Avacopan Avacopan | 1件: D11093
D11093
| 1件: C5AR1 C5AR1 💬 | 6件: Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬 | 3件: 43 43, 44, 222 |
4 | Azathioprine | 1件: Azathioprine Azathioprine | 1件: D00238
D00238
| - | - | 21件: 6 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 |
5 | BELIMUMAB | 1件: Belimumab Belimumab | 1件: D03068
D03068
| 1件: TNFSF13B TNFSF13B 💬 | 4件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | 13件: 11 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 |
6 | Belimumab 10 mg/kg | 1件: Belimumab Belimumab | 1件: D03068
D03068
| 1件: TNFSF13B TNFSF13B 💬 | 4件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | 3件: 43 43, 46, 49 |
7 | Benlysta | 1件: Belimumab Belimumab | 1件: D03068
D03068
| 1件: TNFSF13B TNFSF13B 💬 | 4件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | 5件: 43 43, 49, 53, 66, 222 |
8 | Benlysta 400 mg powder for concentrate for solution for infusion | 1件: Belimumab Belimumab | 1件: D03068
D03068
| 1件: TNFSF13B TNFSF13B 💬 | 4件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | 2件: 43 43, 49 |
9 | Benlysta 400mg polvere per concentrato per soluzione per infusione | 1件: Belimumab Belimumab | 1件: D03068
D03068
| 1件: TNFSF13B TNFSF13B 💬 | 4件: Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | 1件: 43 43 |
10 | Blisibimod | 1件: Blisibimod Blisibimod | 1件: D10311
D10311
| - | - | 5件: 43 43, 44, 49, 63, 66 |
11 | CCX168 | - | - | - | - | 5件: 43 43, 44, 66, 109, 222 |
12 | CELLCEPT | - | - | - | - | 5件: 11 11, 13, 42, 43, 49 |
13 | CellCept (Mycophenolate Mofetil) | 2件: Mycophenolate mofetil Mycophenolate mofetil, Mycophenolic acid | 2件: D00752
D00752
,
D05096
| 2件: IMPDH1 IMPDH1, IMPDH2 💬 | 4件: Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | 2件: 42 42, 43 |
14 | Chimeric monoclonal antibody, IgG4 subtype | - | - | - | - | 2件: 43 43, 44 |
15 | Corticosteroid | - | - | - | - | 9件: 13 13, 42, 43, 44, 45, 66, 96, 97, 222 |
16 | Corticosteroid and azathioprine | 1件: Azathioprine Azathioprine | 1件: D00238
D00238
| - | - | 4件: 42 42, 43, 44, 45 |
17 | Cyclophosphamide | 1件: Cyclophosphamide Cyclophosphamide | 2件: D00287
D00287
,
D07760
| - | - | 44件: 11 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 |
18 | Cyclophosphamide, Azathioprine,prednisone,methylprednisolone | 4件: Azathioprine Azathioprine, Cyclophosphamide, Methylprednisolone, Prednisone | 5件: D00238
D00238
,
D00287
,
D00407
,
D00473
,
D07760
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 3件: 42 42, 43, 45 |
19 | DELTACORTENE | - | - | - | - | 2件: 43 43, 97 |
20 | ENDOXAN | - | - | - | - | 7件: 13 13, 28, 43, 44, 85, 96, 222 |
21 | ENDOXAN BAXTER | - | - | - | - | 3件: 13 13, 43, 96 |
22 | Freeze-Dried Sulfonated Human Normal Immunoglobulin (GGS) | 1件: Human immunoglobulin G Human immunoglobulin G | - | - | - | 3件: 14 14, 43, 45 |
23 | GALEN® tablet | - | - | - | - | 2件: 43 43, 44 |
24 | Glucocorticoid (GC) | - | - | - | - | 2件: 43 43, 44 |
25 | Glucocorticoids | - | - | - | - | 8件: 40 40, 41, 43, 44, 60, 62, 75, 300 |
26 | Glucocorticoids (GC) | - | - | - | - | 2件: 43 43, 44 |
27 | Glucocorticoids - Reduced Dose | - | - | - | - | 2件: 43 43, 44 |
28 | Glucocorticoids - Standard Dose | - | - | - | - | 2件: 43 43, 44 |
29 | Glucocorticoids [Reduced Dose] | - | - | - | - | 2件: 43 43, 44 |
30 | Glucocorticoids [Standard Dose] | - | - | - | - | 2件: 43 43, 44 |
31 | Human normal immunoglobulin | 1件: Human immunoglobulin G Human immunoglobulin G | - | - | - | 9件: 11 11, 13, 14, 43, 45, 50, 51, 63, 65 |
32 | Hydroxychloroquine | 1件: Hydroxychloroquine Hydroxychloroquine | 1件: D08050
D08050
| - | - | 27件: 13 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 |
33 | IFX-1 | 1件: Vilobelimab Vilobelimab | 1件: D11838
D11838
| 1件: C5 C5 💬 | 11件: Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | 3件: 43 43, 44, 269 |
34 | Infliximab | 1件: Infliximab Infliximab | 1件: D02598
D02598
| 1件: TNF TNF 💬 | 67件: AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | 26件: 35 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 |
35 | Intravenous immunoglobulins (human immunoglobulins G) | - | - | - | - | 1件: 43 43 |
36 | Intravenous methyl prednisolone | 1件: Prednisolone Prednisolone | 1件: D00472
D00472
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 1件: 43 43 |
37 | MabThera | 1件: Rituximab Rituximab | 1件: D02994
D02994
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 22件: 11 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271 |
38 | Mabthera® | 1件: Rituximab Rituximab | 1件: D02994
D02994
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 6件: 13 13, 35, 43, 44, 46, 93 |
39 | MabThera® 100MG | 1件: Rituximab Rituximab | 1件: D02994
D02994
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 1件: 43 43 |
40 | MabThera® 500MG | 1件: Rituximab Rituximab | 1件: D02994
D02994
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 1件: 43 43 |
41 | Methotrexate | 1件: Methotrexate Methotrexate | 1件: D00142
D00142
| 2件: DHFR DHFR, DHFR2 💬 | 5件: Antifolate resistance Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬 | 38件: 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 |
42 | Methyl prednisolone | 1件: Prednisolone Prednisolone | 1件: D00472
D00472
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 3件: 43 43, 49, 96 |
43 | Methylprednisolone | 1件: Methylprednisolone Methylprednisolone | 1件: D00407
D00407
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 46件: 2 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 |
44 | Methylprednisolone (or other glucocorticoid) | 1件: Methylprednisolone Methylprednisolone | 1件: D00407
D00407
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 1件: 43 43 |
45 | Mycophenolate | 1件: Mycophenolic acid Mycophenolic acid | 1件: D05096
D05096
| 2件: IMPDH1 IMPDH1, IMPDH2 💬 | 4件: Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | 36件: 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
46 | Mycophenolate mofetil | 2件: Mycophenolate mofetil Mycophenolate mofetil, Mycophenolic acid | 2件: D00752
D00752
,
D05096
| 2件: IMPDH1 IMPDH1, IMPDH2 💬 | 4件: Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | 34件: 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
47 | Mycophenolate mofetil,methotrexate | 3件: Methotrexate Methotrexate, Mycophenolate mofetil, Mycophenolic acid | 3件: D00142
D00142
,
D00752
,
D05096
| 4件: DHFR DHFR, DHFR2, IMPDH1, IMPDH2 💬 | 8件: Antifolate resistance Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, Nucleotide metabolism, One carbon pool by folate, Purine metabolism 💬 | 3件: 42 42, 43, 45 |
48 | Mycophenolic acid | 1件: Mycophenolic acid Mycophenolic acid | 1件: D05096
D05096
| 2件: IMPDH1 IMPDH1, IMPDH2 💬 | 4件: Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | 8件: 11 11, 43, 49, 51, 60, 66, 96, 222 |
49 | Naltrexone | 1件: Naltrexone Naltrexone | 1件: D05113
D05113
| 3件: OPRD1 OPRD1, OPRK1, OPRM1 💬 | 5件: Estrogen signaling pathway Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬 | 12件: 6 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 |
50 | NALTREXONE HYDROCHLORIDE | 1件: Naltrexone Naltrexone | 1件: D05113
D05113
| 3件: OPRD1 OPRD1, OPRK1, OPRM1 💬 | 5件: Estrogen signaling pathway Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬 | 8件: 10 10, 40, 41, 42, 43, 44, 45, 96 |
51 | Obinutuzumab | 1件: Obinutuzumab Obinutuzumab | 1件: D09321
D09321
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 4件: 43 43, 44, 49, 222 |
52 | Pednisone | - | - | - | - | 2件: 43 43, 44 |
53 | Placebo (physiological saline) | - | - | - | - | 2件: 43 43, 45 |
54 | Plaquenil - Hydroxychloroquine 200mg Film coated tablets | 1件: Hydroxychloroquine Hydroxychloroquine | 1件: D08050
D08050
| - | - | 3件: 43 43, 44, 45 |
55 | PREDNISOLONE | 1件: Prednisolone Prednisolone | 1件: D00472
D00472
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 42件: 3 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
56 | Prednison acis® 20 mg | - | - | - | - | 2件: 43 43, 44 |
57 | Prednison acis® 5 mg | - | - | - | - | 2件: 43 43, 44 |
58 | Prednison acis¿ 20 mg | - | - | - | - | 2件: 43 43, 44 |
59 | Prednison acis¿ 5 mg | - | - | - | - | 2件: 43 43, 44 |
60 | Prednisone | 1件: Prednisone Prednisone | 1件: D00473
D00473
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 45件: 2 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 |
61 | Prednisone (and methylprednisolone) | 2件: Methylprednisolone Methylprednisolone, Prednisone | 2件: D00407
D00407
,
D00473
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 1件: 43 43 |
62 | PredniSONE Tablets, USP | 1件: Prednisone Prednisone | 1件: D00473
D00473
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 3件: 41 41, 43, 44 |
63 | Prednisone, methylprednisolone,cyclophosphamides | 2件: Methylprednisolone Methylprednisolone, Prednisone | 2件: D00407
D00407
,
D00473
| 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 3件: 42 42, 43, 45 |
64 | Remission induction therapy | - | - | - | - | 2件: 43 43, 44 |
65 | RITUXIMAB | 1件: Rituximab Rituximab | 1件: D02994
D02994
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 48件: 11 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 |
66 | Rituximab (Arm A) | 1件: Rituximab Rituximab | 1件: D02994
D02994
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 2件: 43 43, 44 |
67 | Rituximab (Arm B) | 1件: Rituximab Rituximab | 1件: D02994
D02994
| 1件: MS4A1 MS4A1 💬 | 1件: Hematopoietic cell lineage Hematopoietic cell lineage 💬 | 2件: 43 43, 44 |
68 | RIXATHON 500mg | - | - | - | - | 1件: 43 43 |
69 | RO0452294/V01 | - | - | - | - | 2件: 43 43, 44 |
70 | RO0452294/V02 | - | - | - | - | 3件: 35 35, 43, 44 |
71 | Ro106-1443 | - | - | - | - | 1件: 43 43 |
72 | Sendoxan | - | - | - | - | 2件: 13 13, 43 |
73 | Tocilizumab | 1件: Tocilizumab Tocilizumab | 1件: D02596
D02596
| 1件: IL6R IL6R 💬 | 12件: Coronavirus disease - COVID-19 Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬 | 21件: 2 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 |
74 | Vilobelimab | 1件: Vilobelimab Vilobelimab | 1件: D11838
D11838
| 1件: C5 C5 💬 | 11件: Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | 2件: 43 43, 44 |
75 | Vitamin D | 1件: Vitamin D Vitamin D | - | - | - | 20件: 13 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299 |