45. 好酸球性多発血管炎性肉芽腫症 Eosinophilic granulomatosis with Polyangiitis Clinical trials / Disease details
臨床試験数 : 31 / 薬物数 : 44 - (DrugBank : 18) / 標的遺伝子数 : 18 - 標的パスウェイ数 : 101
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04316494 (ClinicalTrials.gov) | December 17, 2020 | 25/2/2020 | Hydroxychloroquine in ANCA Vasculitis Evaluation | Hydroxychloroquine in ANCA Vasculitis Evaluation - A Multicentre, Randomised, Double-blind, Placebo-controlled Trial | ANCA Associated Vasculitis;Microscopic Polyangiitis;Churg-Strauss Syndrome;Wegener Granulomatosis | Drug: Hydroxychloroquine;Drug: Placebo | Guy's and St Thomas' NHS Foundation Trust | Medical Research Council | Recruiting | 18 Years | N/A | All | 76 | Phase 4 | United Kingdom |
| 2 | EUCTR2018-001268-40-GB (EUCTR) | 23/01/2020 | 13/09/2019 | Hydroxychloroquine in ANCA vasculitis | Hydroxychloroquine in ANCA Vasculitis Evaluation - A Multicentre, Randomised, Double-blind, Placebo-controlled Trial - HAVEN | The term ANCA-associated vasculitis (AAV) describes a subset of primary small vessel vasculitides characterized by the presence of anti-neutrophil cytoplasmic antibodies (ANCA): Granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and Eosinophilic Granulomatosis with Polyangiitis (EGPA). AAV are serious multisystem autoimmune disorders that can affect any organ in the body and commonly involve the ear-nose-throat, lungs, kidneys, eyes and joints MedDRA version: 20.0;Level: SOC;Classification code 10021428;Term: Immune system disorders;System Organ Class: 10021428 - Immune system disorders;Therapeutic area: Body processes [G] - Immune system processes [G12] | Trade Name: Plaquenil - Hydroxychloroquine 200mg Film coated tablets | Guy's and St. Thomas' NHS Foundation Trust | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 76 | Phase 4 | United Kingdom |