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Drug
Target Gene/Pathway
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Drug
Description in Trials
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drugs per page:
Showing 1 to 10 of 18 drugs
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No.
DrugBank
薬物名(臨床試験情報から抽出)
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Azathioprine
3件:
Azathioprine
Azathioprine
;
AZATIOPRINA
;
Imuran
1件:
D00238
D00238
-
-
21件:
6
6
,
11
,
13
,
19
,
35
,
42
,
43
,
44
,
45
,
46
,
49
,
63
,
65
,
66
,
85
,
93
,
94
,
95
,
96
,
97
,
162
2
Benralizumab
2件:
Benralizumab
Benralizumab
;
Fasenra
1件:
D09874
D09874
1件:
IL5RA
IL5RA
💬
4件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Hematopoietic cell lineage
,
JAK-STAT signaling pathway
,
Pathways in cancer
💬
4件:
Cytokine-cytokine receptor interaction
,
Hematopoietic cell lineage
,
JAK-STAT signaling pathway
, ...
5件:
44
44
,
45
,
98
,
162
,
299
3
Coenzyme M
2件:
MESNA
MESNA
;
UROMITEXAN
-
-
-
10件:
11
11
,
13
,
44
,
45
,
51
,
60
,
65
,
85
,
96
,
164
4
Cyclophosphamide
6件:
Ciclofosfamida
Ciclofosfamida
;
Ciclofosfamide
;
Cyclophosphamid
;
Cyclophosphamide
;
Cyclophosphamidum
;
Cytoxan
2件:
D00287
D00287
,
D07760
-
-
44件:
11
11
,
13
,
14
,
16
,
19
,
20
,
26
,
28
,
35
,
36
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
52
,
56
,
60
,
62
,
65
,
66
,
84
,
85
,
93
,
96
,
162
,
164
,
172
,
205
,
222
,
224
,
256
,
274
,
283
,
284
,
285
,
288
,
326
,
331
44件:
11
,
13
,
14
,
16
,
19
,
20
,
26
,
28
,
35
,
36
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
52
,
56
,
60
,
62
, ...
5
Cyclosporine
10件:
CICLOSPORIN
CICLOSPORIN
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine A
;
Ikervis
;
Neoral
;
RESTASIS
10件:
CICLOSPORIN
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine
...
1件:
D00184
D00184
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
44件:
11
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
,
65
,
90
,
93
,
95
,
97
,
107
,
113
,
162
,
164
,
222
,
226
,
228
,
234
,
269
,
274
,
283
,
284
,
285
,
302
,
326
44件:
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
, ...
6
Filgrastim
7件:
Filgrastim
Filgrastim
;
Filgrastim Hexal
;
G-CSF
;
Granulocyte Colony Stimulating Factor
;
Neupogen
;
TEVAGRASTIM
;
Zarzio
7件:
Filgrastim
;
Filgrastim Hexal
;
G-CSF
;
Granulocyte Colony Stimulating Factor
;
Neupogen
;
TEVAGRASTI
...
1件:
D03235
D03235
1件:
CSF3R
CSF3R
💬
5件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Hematopoietic cell lineage
,
JAK-STAT signaling pathway
,
PI3K-Akt signaling pathway
,
Pathways in cancer
💬
5件:
Cytokine-cytokine receptor interaction
,
Hematopoietic cell lineage
,
JAK-STAT signaling pathway
, ...
35件:
2
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
65
,
85
,
96
,
113
,
164
,
256
,
283
,
284
,
285
,
296
,
331
35件:
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
6
...
7
Human immunoglobulin G
19件:
Bivigam
Bivigam
;
CUTAQUIG
;
CUVITRU
;
GAMMAGARD LIQUID
;
Gammaplex
;
GAMUNEX-C
;
Hizentra
;
HUMAN IMMUNOGLOBULIN G
;
Human normal immunoglobulin
;
HyQvia
;
Immune globulin
;
Immunoglobulin
;
IMMUNOGLOBULIN G
;
IVIg
;
KIOVIG
;
Octagam
;
PANZYGA
;
Privigen
;
Vivaglobin
19件:
Bivigam
;
CUTAQUIG
;
CUVITRU
;
GAMMAGARD LIQUID
;
Gammaplex
;
GAMUNEX-C
;
Hizentra
;
HUMAN IMMUNOGLOBU
...
-
-
-
10件:
11
11
,
13
,
14
,
17
,
43
,
45
,
50
,
51
,
63
,
65
8
Hydroxychloroquine
3件:
Hydroxychloroquine
Hydroxychloroquine
;
Hydroxychloroquine sulfate
;
PLAQUENIL
1件:
D08050
D08050
-
-
27件:
13
13
,
34
,
41
,
43
,
44
,
45
,
46
,
48
,
49
,
53
,
56
,
63
,
66
,
84
,
89
,
90
,
96
,
97
,
107
,
218
,
222
,
224
,
234
,
254
,
271
,
298
,
299
27件:
13
,
34
,
41
,
43
,
44
,
45
,
46
,
48
,
49
,
53
,
56
,
63
,
66
,
84
,
89
,
90
,
96
,
97
,
107
,
218
,
222
,
224
,
234
...
9
Infliximab
6件:
Flixabi
Flixabi
;
Inflectra
;
Infliximab
;
Remicade
;
REMSIMA
;
Zessly
1件:
D02598
D02598
1件:
TNF
TNF
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
27件:
35
35
,
37
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
55
,
56
,
65
,
84
,
85
,
95
,
96
,
97
,
98
,
107
,
162
,
164
,
269
,
270
,
271
27件:
35
,
37
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
55
,
56
,
65
,
84
,
85
,
95
,
96
,
97
,
98
,
107
,
162
,
1
...
10
Mepolizumab
2件:
Mepolizumab
Mepolizumab
;
NUCALA
1件:
D04923
D04923
1件:
IL5
IL5
💬
13件:
Allograft rejection
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
,
Fc epsilon RI signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Pathways in cancer
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
💬
13件:
Allograft rejection
,
Asthma
,
Autoimmune thyroid disease
,
Cytokine-cytokine receptor interaction
...
4件:
44
44
,
45
,
98
,
162