6. パーキンソン病 Parkinson disease Clinical trials / Disease details
臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199
Showing 1 to 10 of 17 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | ChiCTR2200059588 | 2022-06-01 | 2022-05-04 | Analysis of speech disorders in patients with Parkinson's disease based on speech signals and machine learning Analysis of speech disorders in patients with Parkinson's disease based on speech signals and machin ... | Analysis of speech disorders in patients with Parkinson's disease based on speech signals and machine learning Analysis of speech disorders in patients with Parkinson's disease based on speech signals and machin ... | Parkinson's Disease | Gold Standard:Parkinson's speech features that can be used for recognition ;Index test:Extract the multi-modal speech features of Parkinson's patients using the developed speech signal processing algorithm ; GoldStandard:Parkinson's speech features that can be used for recognition ;Index test:Extract the mu ... | Provincial Government Hospital in Jiangsu Province | NULL | Pending | 18 | 75 | Both | Target condition:200;Difficult condition:0 | N/A | China |
2 | ChiCTR2200059544 | 2021-09-01 | 2022-05-04 | Nomogram for Prediction of Postoperative Delirium after Deep Brain Stimulation of Subthalamic Nucleus in Parkinson's Disease under General Anesthesia Nomogram for Prediction of Postoperative Delirium after Deep Brain Stimulation of Subthalamic Nucleu ... | Nomogram for Prediction of Postoperative Delirium after Deep Brain Stimulation of Subthalamic Nucleus in Parkinson's Disease under General Anesthesia Nomogram for Prediction of Postoperative Delirium after Deep Brain Stimulation of Subthalamic Nucleu ... | Parkinson's disease | Gold Standard:Clinical outcome;Index test:The clinical prediction model of delirium after deep brain stimulation of the subthalamic nucleus in Parkinson's disease under general anesthesia.; GoldStandard:Clinical outcome;Index test:The clinical prediction model of delirium after deep brain ... | First Affiliated Hospital of Sun Yat-sen University | NULL | Completed | 18 | 80 | Both | Target condition:240;Difficult condition:0 | China | |
3 | ChiCTR2100044662 | 2021-04-01 | 2021-03-25 | Study on exosome biomarkers in Parkinson's disease | Study on exosome biomarkers in Parkinson's disease | Parkinson’s disease | Gold Standard:Clinically established Parkinson's disease conforming to China Diagnostic Criteria for Parkinson's Disease (2016);Index test:Exosome biomarkers (miRNA and a-synuclein); GoldStandard:Clinically established Parkinson's disease conforming to China Diagnostic Criteria for ... | The First Affiliated Hospital, Sun Yat-sen University | NULL | Recruiting | 21 | 100 | Both | Target condition:1200;Difficult condition:0 | China | |
4 | ChiCTR2000038937 | 2020-11-01 | 2020-10-10 | Clinical study of early diagnosis of Parkinson's disease based on substantia nigra-striatal axis multimodal imaging Clinical study of early diagnosis of Parkinson's disease based on substantia nigra-striatal axis mul ... | Clinical study of early diagnosis of Parkinson's disease based on substantia nigra-striatal axis multimodal imaging Clinical study of early diagnosis of Parkinson's disease based on substantia nigra-striatal axis mul ... | Parkinson's disease | Gold Standard:Clinical diagnosis by experienced movement disorder specialists after 2 years of follow-up.;Index test:Including traditional imaging feature algorithms (SUVR value, total cortical volume, bilateral cortical surface area, cortical thickness, etc.), high-dimensional imaging omics feature algorithms (energy entropy, gray-level co-occurrence matrix, and mutual information, etc.), and brain connection group Learning feature algorithm.; GoldStandard:Clinical diagnosis by experienced movement disorder specialists after 2 years of follow ... | Huashan Hospital, Fudan University | NULL | Recruiting | 45 | 80 | Both | Target condition:105;Difficult condition:0 | China | |
5 | ChiCTR2000037856 | 2020-10-01 | 2020-09-02 | Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA) Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by ... | Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA) Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by ... | Parkinson's Disease | Gold Standard:DAT-PET and 18F-FDG PET ;Index test:a-synuclein protein misfolding cyclic amplification; GoldStandard:DAT-PET and 18F-FDGPET ;Index test:a-synuclein protein misfolding cyclic amplification; ... | Huashan Hospital Affiliated to Fudan University | NULL | Recruiting | 50 | 75 | Both | Target condition:150;Difficult condition:76 | China | |
6 | ChiCTR2000036137 | 2020-10-01 | 2020-08-21 | Clinical study of 18F-FDG combined with 18F-AV-133 PET/CT imaging in the diagnosis and differentiation of primary Parkinson's disease Clinical study of 18F-FDG combined with 18F-AV-133 PET/CT imaging in the diagnosis and differentiati ... | Clinical study of 18F-FDG combined with 18F-AV-133 PET/CT imaging in the diagnosis and differentiation of primary Parkinson's disease Clinical study of 18F-FDG combined with 18F-AV-133 PET/CT imaging in the diagnosis and differentiati ... | Parkinson’s disease | Gold Standard:UK Parkinson's disease Society Brain Bank Clinical Diagnosis Criteria;Index test:18F-FDG combined with 18F-AV-133 PET/CT imaging; GoldStandard:UK Parkinson's disease Society Brain Bank Clinical Diagnosis Criteria;Index test:18F-FD ... | Renji Hospital (South Court), School of Medicine, Shanghai Jiao Tong University | NULL | Pending | Both | Target condition:50;Difficult condition:0 | China | |||
7 | ChiCTR2000037239 | 2020-10-01 | 2020-08-27 | Construction and application of a diagnostic marker for Parkinson's disease based on gut microbiomics Construction and application of a diagnostic marker for Parkinson's disease based on gut microbiomic ... | Construction and application of a diagnostic marker for Parkinson's disease based on gut microbiomics Construction and application of a diagnostic marker for Parkinson's disease based on gut microbiomic ... | Parkinson's disease | Gold Standard:All patients satisfied the United Kingdom Parkinson's Disease Society Brain Bank criteria;Index test:Microbial gene detection chip; GoldStandard:All patients satisfied the United Kingdom Parkinson's Disease Society Brain Bank criter ... | Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine | NULL | Recruiting | 55 | 80 | Both | Target condition:500;Difficult condition:600 | China | |
8 | ChiCTR2000036006 | 2020-10-01 | 2020-08-21 | The applications of multi- MRI in early diagnosis of Parkinson's Disease based on deep learning | The applications of multi- MRI in early diagnosis of Parkinson's Disease based on deep learning | Parkinson's disease | Gold Standard:MDS clinical diagnostic criteria for Parkinson’s disease;Index test:multimodal MRI features in locus coeruleus and substantia nigra; GoldStandard:MDS clinical diagnostic criteria for Parkinson’s disease;Index test:multimodal MRI feat ... | Zhongshan Hospital, Fudan University | NULL | Pending | 18 | 85 | Both | Target condition:400;Difficult condition:0 | China | |
9 | ChiCTR2000032616 | 2020-05-30 | 2020-05-04 | Assistant diagnosis machinery system development based on speech and movement sensitive device for Parkinson's disease Assistant diagnosis machinery system development based on speech and movement sensitive device for P ... | Parkinson's disease, Assistant diagnosis machinery system, speech, movement sensitive device | Parkinson's disease | Gold Standard:clinical outcome meet 2015 MDS-probable PD criteria;Index test:Acoustic receptive and analysis device,Wearable movement sensor; GoldStandard:clinical outcome meet 2015 MDS-probable PD criteria;Index test:Acoustic receptive and a ... | Shanghai Jiao Tong University School of Medicine affiliated Shanghai General Hospital | NULL | Pending | Both | Target condition:20;Difficult condition:80 | China | |||
10 | NCT03815916 (ClinicalTrials.gov) | December 19, 2019 | 18/1/2019 | 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's Disease 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's Dis ... | A Phase 2, Pilot Open Label, Sequential Group, Investigator Blinded Study of Magnetic Resonance Spectroscopy (31P-MRS) to Assess the Effects of CNM-Au8 for the Bioenergetic Improvement of Impaired Neuronal Redox State in Parkinson's Disease A Phase 2, Pilot Open Label, Sequential Group, Investigator Blinded Study of Magnetic Resonance Spec ... | Parkinson's Disease | Drug: Gold Nanocrystals | Clene Nanomedicine | University of Texas Southwestern Medical Center | Completed | 30 Years | 80 Years | All | 13 | Phase 2 | United States |