Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 7-beta-Hydroxyepiandrosterone 1件: 7-beta-Hydroxyepiandrosterone---1件: 6
2 8-hydroxy-2'-deoxyguanosine 1件: 8-OHdG---1件: 6
3 Acamprosate 1件: Acamprosate1件: D07058 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 6, 206
4 Acetaminophen 4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
5 Acetate 1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
6 Acetic acid C-11 1件: 11C-ACETATE---4件: 6, 13, 86, 88
7 Acetylcysteine 3件: Acetylcysteine; Mucomyst; N-acetylcysteine1件: D00221 --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
8 ACR325 1件: ACR325---1件: 6
9 Activated charcoal 1件: Carbon---6件: 6, 85, 86, 96, 97, 158
10 Ademetionine 2件: SAM-e; SAMe1件: D07128 --2件: 6, 93
11 Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins 1件: HB-adMSCs---5件: 2, 6, 13, 14, 46
12 Agomelatine 1件: Agomelatine1件: D02578 3件: HTR2C,
MTNR1A,
MTNR1B 💬		6件: Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6
13 Alanine 2件: Alanine; L-alanine1件: D00012 --4件: 6, 13, 298, 299
14 Albendazole 2件: Albendazole; Eskazole1件: D00134 --12件: 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127
15 Alirinetide 2件: GM604; GM608---2件: 2, 6
16 Allopurinol 2件: Allopurinol; ALLOPURINOL SODIUM1件: D00224 1件: XDH 💬6件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬7件: 6, 46, 57, 60, 66, 96, 97
17 Altropane 1件: Altropane---1件: 6
18 Amantadine 3件: Amantadine; AMANTADINE HYDROCHLORIDE; GOCOVRI1件: D07441 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬4件: 6, 8, 13, 127
19 Ambroxol 1件: Ambroxol1件: D07442 --2件: 6, 19
20 Ammonia 1件: Ammonia1件: D02916 --2件: 6, 296
21 Amoxicillin 4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin2件: D00229 ,
D07452 		--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
22 Ampicillin 1件: ABPC1件: D00204 --5件: 2, 6, 13, 84, 299
23 Ampreloxetine 1件: Ampreloxetine1件: D11688 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 17
24 anle138b 1件: Anle138b---1件: 6
25 Apigenin 1件: Apigenin---2件: 6, 97
26 Aplindore 1件: Aplindore---1件: 6
27 Apomorphine 4件: APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride1件: D07460 2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
28 Aripiprazole 1件: Aripiprazole1件: D01164 4件: DRD2,
DRD3,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206
29 Armodafinil 2件: Armodafinil; MODAFINIL1件: D03215 1件: SLC6A3 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬3件: 6, 13, 84
30 Aspartame 0件: 1件: D02381 2件: TAS1R2,
TAS1R3 💬		2件: Carbohydrate digestion and absorption, Taste transduction 💬4件: 6, 13, 67, 86
31 Atomoxetine 2件: Atomoxetine; Strattera1件: D07473 1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17
32 AV-101 1件: AV-101---2件: 6, 86
33 Azathioprine 3件: Azathioprine; Azatioprina; Imuran1件: D00238 --21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
34 AZD-0328 0件: ---1件: 6
35 Bavisant 1件: Bavisant1件: D09870 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬1件: 6
36 Benserazide 1件: BENSERAZIDE1件: D03082 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
37 Benzofuran 1件: Benzofuran---1件: 6
38 BIA 1件: BIA---2件: 6, 86
39 Botulinum toxin type A 8件: Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
40 Botulinum toxin type B 3件: Botulinum toxin type B; MYOBLOC; NEUROBLOC1件: D02735 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬4件: 2, 6, 13, 51
41 Bromocriptine 1件: Bromocriptine1件: D03165 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 74
42 BTRX-246040 1件: BTRX-246040---1件: 6
43 Bumetanide 1件: Bumetanide1件: D00247 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬2件: 6, 158
44 Buspirone 2件: Buspirone; Buspirone Hydrochloride1件: D07593 2件: DRD2,
HTR1A 💬		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 51
45 Butylphthalide 1件: Butylphthalide---4件: 2, 6, 18, 22
46 Cabergoline 3件: CABERGOLINA; Cabergoline; DOSTINEX1件: D00987 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 74, 75
47 Caffeine 1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
48 Calcium 2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
49 Cannabidiol 4件: CANNABIDIOL; Epidiolex; Epidyolex; Sativex1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
50 Capsaicin 2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
51 Captopril 1件: Captopril1件: D00251 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬8件: 6, 17, 46, 86, 96, 97, 107, 271
52 Carbamazepine 1件: Carbamazepine1件: D00252 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 6, 13, 231
53 Carbidopa 8件: Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201
54 Carnosine 1件: Carnosine---2件: 6, 13
55 Ceftriaxone 1件: Ceftriaxone1件: D07659 --4件: 2, 6, 46, 97
56 CEP-1347 1件: CEP-1347---1件: 6
57 Chamomile 2件: Chamomile; MATRICARIA FLOWER1件: D09212 --2件: 6, 97
58 Chloride ion 1件: Chloride---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
59 Cholecalciferol 5件: Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
60 Citalopram 1件: Citalopram1件: D07704 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
61 Citicoline 1件: Citicolina1件: D00057 --1件: 6
62 Clarithromycin 1件: CLARITHROMYCIN1件: D00276 --8件: 6, 63, 84, 96, 97, 222, 228, 299
63 Clenbuterol 1件: Clenbuterol1件: D07713 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 1, 2, 6, 13, 256
64 Clonazepam 1件: Clonazepam1件: D00280 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6
65 Clonidine 4件: Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE1件: D00281 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
66 Clozapine 1件: CLOZAPINE1件: D00283 11件: ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		8件: Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬1件: 6
67 Cobalt chloride 1件: Ceretec---1件: 6
68 Cocoa 2件: Chocolate; Cocoa---1件: 6
69 Creatine 1件: Creatine---11件: 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201
70 Crocin 1件: Crocin---1件: 6
71 Cultivated mushroom 1件: Mushroom---2件: 6, 46
72 Cyanocobalamin 2件: Cianocobalamina; Vitamin B124件: D00166 ,
D03615 ,
D03616 ,
D03617 		--5件: 6, 13, 201, 229, 299
73 D-Serine 1件: D-Serine---1件: 6
74 Dalfampridine 7件: 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; FAMPYRA1件: D04127 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14
75 Darifenacin 2件: Darifenacin; Emselex1件: D03654 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 6, 13
76 Deanol 1件: Deanol1件: D07777 --1件: 6
77 Deferiprone 2件: Deferiprone; Ferriprox1件: D07416 --6件: 2, 6, 18, 120, 122, 233
78 Delorazepam 0件: 1件: D07784 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 6, 46, 97
79 Desmopressin 5件: DDAVP; Desmopressin; Desmopressin Acetate; Desmopressine; Minirin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288
80 Dexmedetomidine 4件: Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE1件: D00514 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
81 Dextromethorphan 4件: Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta1件: D03742 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
82 Dextrose, unspecified form 3件: Dextrose; Glucose; Smofkabiven---16件: 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299
83 Dichloroisoproterenol 0件: ---2件: 6, 299
84 Dihydroergotoxine 1件: Dihydroergotoxine1件: D07839 --1件: 6
85 Dihydrotachysterol 0件: 1件: D00299 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 6, 85
86 Dipivefrin 2件: Dipivefrin; Dipivefrine1件: D02349 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
87 Dipraglurant 1件: Dipraglurant---1件: 6
88 Doconexent 2件: Docosahexaenoic acid; Docosahexanoic Acid---10件: 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
89 Domperidone 1件: Domperidone2件: D01745 ,
D07868 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
90 Donepezil 3件: Aricept; Donepezil; Donepezil hydrochloride1件: D07869 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
91 Dopamine 2件: Dopamina; Dopamine1件: D07870 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 7, 74, 299
92 Doxepin 1件: Doxepin1件: D07875 3件: HRH1,
SLC6A2,
SLC6A4 💬		5件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 6
93 Droxidopa 4件: DOPS; Droxidopa; L-DOPS; Northera1件: D01277 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170
94 Duloxetine 3件: Cymbalta; DULOXETINE; Duloxetine hydrochloride1件: D07880 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13
95 Edaravone 3件: Edaravone; Methylphenylpyrazolone; Norphenazone1件: D01552 --3件: 2, 6, 22
96 Eliprodil 1件: Eliprodil---1件: 6
97 Elobixibat 1件: Elobixibat1件: D10796 1件: SLC10A2 💬1件: Bile secretion 💬1件: 6
98 Eltoprazine 1件: ELTOPRAZINE---1件: 6
99 Entacapone 5件: COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo1件: D00781 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬2件: 6, 17
100 EPI-589 1件: EPI-589---2件: 2, 6
101 Epigallocatechin gallate 3件: EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate---9件: 6, 8, 13, 17, 28, 85, 113, 206, 299
102 Ergoloid mesylate 2件: Dihydroergotoxine Mesylate; Ergoloid Mesylate---2件: 6, 206
103 Erythromycin 1件: Erythromycin1件: D00140 --5件: 6, 36, 164, 228, 291
104 Erythropoietin 4件: EPOETIN ALFA; Epoetin beta; Erythropoietin; Neorecormon---10件: 2, 6, 13, 18, 22, 46, 47, 70, 95, 96
105 Escitalopram 3件: Citalopram; Escitalopram; Escitalopram oxalate1件: D07913 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 2, 6, 13, 46
106 Eszopiclone 2件: Eszopiclone; Zopiclone1件: D02624 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 6, 13, 46
107 Etomidate 1件: Etomidate1件: D00548 1件: GABRA1 💬6件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬1件: 6
108 Exametazime 1件: Exametazime1件: D01109 --1件: 6
109 Exenatide 3件: BYDUREON; Byetta; Exenatide1件: D04121 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233
110 Famotidine 2件: FAMOTIDINA; Famotidine1件: D00318 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬6件: 6, 46, 61, 86, 98, 107
111 Febuxostat 1件: Febuxostat1件: D01206 1件: XDH 💬6件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬3件: 2, 6, 13
112 Fesoterodine 1件: Fesoterodine1件: D07226 2件: CHRM2,
CHRM3 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6
113 Filgrastim 7件: Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; NEUPOGEN; TEVAGRASTIM; Zarzio1件: D03235 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
114 Finasteride 1件: Finasteride1件: D00321 1件: SRD5A2 💬3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬1件: 6
115 Fipamezole 1件: Fipamezole---2件: 6, 17
116 Flecainide 3件: Flecainide; FLECAINIDE ACETATE; Flecainidum1件: D07962 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6
117 Florbenazine F-18 1件: 18F-AV-133---1件: 6
118 Florbetaben (18F) 2件: FLORBETABEN (18F); Neuraceq---1件: 6
119 Fludeoxyglucose (18F) 2件: 18F-FDG; Fludeoxyglucose---8件: 5, 6, 7, 13, 84, 85, 127, 300
120 Fludrocortisone 1件: Fludrocortisone1件: D07967 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬3件: 6, 17, 81
121 Flumazenil 1件: Flumazenil1件: D00697 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206
122 Flutemetamol 1件: Flutemetamol---4件: 5, 6, 7, 127
123 Folic acid 5件: Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE1件: D00070 --6件: 6, 41, 46, 49, 84, 296
124 Foliglurax 1件: Foliglurax---1件: 6
125 Foscarbidopa 1件: Foscarbidopa1件: D12057 --1件: 6
126 Foslevodopa 1件: Foslevodopa1件: D11839 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
127 Furosemide 2件: Furosemide; Furosemide Injection1件: D00331 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬2件: 6, 86
128 Gabapentin 4件: GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
129 Galantamine 2件: GALANTAMINE; Galantamine hydrobromide1件: D04292 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127
130 gamma-Hydroxybutyric acid 1件: Oxybate---2件: 6, 149
131 Ginkgo biloba 3件: Ginkgo; Ginkgo biloba; Tanakan---5件: 6, 13, 18, 47, 90
132 Glutathione 2件: GLUTATHIONE; Reduced glutathione2件: D00014 ,
D00031 		--2件: 6, 299
133 Glycerin 2件: Bee venom; Glycerol1件: D00028 --5件: 6, 13, 79, 316, 317
134 Glycerol phenylbutyrate 3件: Glycerol Phenylbutyrate; GT4P; RAVICTI1件: D10127 --3件: 6, 251, 299
135 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
136 GPI-1485 0件: ---1件: 6
137 Grapefruit 1件: Grapefruit---5件: 6, 46, 50, 83, 97
138 Green tea leaf 4件: Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract1件: D06903 --4件: 6, 17, 28, 46
139 Guar gum 1件: Guar gum1件: D04403 --1件: 6
140 Heptaminol 1件: Heptaminol1件: D07158 --1件: 6
141 Hydrocortisone 6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
142 Hydrocortisone cypionate 1件: Cortef1件: D00976 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 81, 83
143 Hydrocortisone succinate 2件: HYDROCORTISONE HYDROGEN SUCCINATE; Solu-Cortef1件: D01442 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 81, 83
144 Hydrogen 2件: Dihydrogen; Hydrogen---7件: 5, 6, 17, 65, 83, 97, 226
145 Idebenone 2件: Idebenone; Raxone1件: D01750 --6件: 6, 8, 13, 18, 113, 302
146 Iloperidone 1件: Iloperidone1件: D02666 4件: DRD2,
HTR2A,
HTR2B,
HTR2C 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬1件: 6
147 Inosine 1件: Inosine1件: D00054 --6件: 2, 6, 13, 17, 85, 122
148 Interleukin-1 alpha, human recombinant 1件: None---18件: 6, 46, 51, 65, 66, 84, 85, 96, 97, 140, 161, 171, 222, 231, 246, 271, 299, 337
149 Inulin 1件: Inulin1件: D00171 --4件: 6, 96, 156, 299
150 Iodide I-123 2件: I 123; I-123---2件: 2, 6
151 Ioflupane I-123 3件: DaTSCAN; Ioflupane; Ioflupane I 123---3件: 2, 5, 6
152 Ipratropium 1件: Ipratropium---2件: 6, 86
153 Iproniazid 1件: IPRONIAZID1件: D02579 2件: MAOA,
MAOB 💬		14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
154 Isoflurane 1件: Isoflurane1件: D00545 --1件: 6
155 Isoxaflutole 1件: Balance---5件: 6, 11, 46, 81, 149
156 Isradipine 1件: Isradipine1件: D00349 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
157 Istradefylline 1件: ISTRADEFYLLINE1件: D04641 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
158 ITI-214 1件: ITI-214---1件: 6
159 Josamycin 0件: 1件: D01235 --2件: 6, 13
160 KDT-3594 1件: KDT-3594---1件: 6
161 Ketamine 2件: Ketamine; NMDA1件: D08098 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 4, 6, 13, 70, 113, 156, 215
162 KW-6356 1件: KW-6356---1件: 6
163 Lactobacillus acidophilus 4件: Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus1件: D04349 --3件: 6, 49, 97
164 Lactobacillus casei 2件: Fusion; Lactobacillus casei1件: D04351 --10件: 6, 11, 13, 46, 49, 69, 70, 97, 271, 296
165 Lactobacillus delbrueckii bulgaricus 1件: Lactobacillus---5件: 6, 46, 51, 97, 299
166 Lactobacillus plantarum 1件: Lactobacillus plantarum---3件: 6, 97, 156
167 Lactose 1件: Lactose2件: D00046 ,
D03226 		--6件: 2, 6, 13, 97, 228, 310
168 Lenomorelin 1件: Ghrelin---6件: 6, 78, 193, 201, 202, 299
169 Leptin 1件: Leptin---2件: 6, 265
170 Leucine 2件: L-leucine; Leucine1件: D00030 --6件: 6, 19, 65, 283, 284, 299
171 Levetiracetam 2件: KEPPRA; Levetiracetam1件: D00709 1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307
172 Levodopa 9件: Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬6件: 6, 17, 90, 140, 164, 201
173 Levomefolic acid 1件: L-methylfolate1件: D09353 --2件: 6, 201
174 Liatermin 2件: Liatermin; R-metHuGDNF1件: D04727 --1件: 6
175 Lidocaine 4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
176 Linaclotide 1件: Linaclotide1件: D09355 1件: GUCY2C 💬2件: Metabolic pathways, Purine metabolism 💬2件: 6, 97
177 Linoleic acid 1件: Linoleic acid---8件: 2, 5, 6, 13, 76, 78, 256, 299
178 Liraglutide 2件: Liraglutide; Saxenda1件: D06404 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 6, 75, 193
179 Lisuride 1件: LISURIDE1件: D08132 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 86
180 Lithium citrate 2件: Lithium; LITHIUM CITRATE1件: D04749 --5件: 2, 5, 6, 7, 8
181 Lixisenatide 1件: Lixisenatide1件: D09729 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6
182 Lovastatin 1件: LOVASTATIN1件: D00359 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
183 Lubiprostone 1件: Lubiprostone1件: D04790 1件: CLCN2 💬1件: Mineral absorption 💬4件: 6, 13, 290, 299
184 Magnesium 1件: Magnesium---19件: 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298
185 Magnesium oxide 1件: Magnesium Oxide1件: D01167 --3件: 6, 166, 291
186 Maltodextrin 1件: Maltodextrin1件: D02329 --4件: 6, 13, 96, 97
187 Manganese citrate 1件: Release---12件: 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
188 Mannitol 4件: Aridol; Bronchitol; Mannite; MANNITOL1件: D00062 --7件: 6, 13, 28, 60, 96, 113, 299
189 Masitinib 1件: MASITINIB1件: D10229 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬6件: 2, 5, 6, 13, 46, 96
190 Mavoglurant 1件: Mavoglurant---2件: 6, 206
191 MC-1 0件: ---1件: 6
192 Medical Cannabis 3件: Cannabis; Marijuana; Medical Cannabis---7件: 2, 6, 13, 19, 90, 96, 97
193 Medium-chain triglycerides 3件: Medium chain triglyceride; Smofkabiven; SMOFLipid---5件: 6, 66, 96, 296, 318
194 Melatonin 2件: Circadin; Melatonin1件: D08170 2件: MTNR1A,
MTNR1B 💬		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬12件: 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202
195 Melevodopa 1件: Melevodopa1件: D07304 --1件: 6
196 Melperone 1件: Melperone1件: D07309 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
197 Memantine 3件: Ebixa; MEMANTINE; MEMANTINE HYDROCHLORIDE1件: D08174 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206
198 Mesdopetam 1件: Mesdopetam---1件: 6
199 Metformin 5件: Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine1件: D04966 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
200 Methylphenidate 3件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin1件: D04999 2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206
201 Midazolam 2件: Midazolam; Midazolam injection1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
202 Midodrine 2件: Midodrine; MIDODRINE HYDROCHLORIDE1件: D08220 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 6, 17, 58
203 Minocycline 3件: Minocycline; MINOCYCLINE HYDROCHLORIDE; Minomycin1件: D05045 --14件: 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
204 Minodronic acid 2件: Minodronate; Minodronic acid---4件: 6, 46, 93, 95
205 Mirabegron 1件: Mirabegron1件: D09535 1件: ADRB3 💬8件: Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬4件: 6, 13, 53, 226
206 Mitoquinone 1件: Mitoquinone---3件: 6, 13, 97
207 Moclobemide 1件: MOCLOBEMIDE1件: D02561 1件: MAOA 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
208 Modafinil 2件: Modafinil; Provigil1件: D01832 --5件: 6, 13, 49, 93, 113
209 Montelukast 3件: Montelukast; MONTELUKAST SODIUM; Singulair1件: D08229 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
210 Moxifloxacin 2件: Moxifloxacin; Moxifloxacin hydrochloride1件: D08237 --9件: 2, 6, 46, 49, 85, 86, 113, 240, 299
211 Muscimol 1件: Muscimol---1件: 6
212 Nabilone 1件: Nabilone1件: D05099 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬3件: 6, 13, 127
213 Nadolol 1件: Nadolol1件: D00432 2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
214 Nalmefene 1件: Nalmefene1件: D05111 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
215 Naloxone 2件: Naloxone; NALOXONE HYDROCHLORIDE1件: D08249 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 6, 226
216 Naltrexone 2件: Naltrexone; Naltrexone Hydrochloride1件: D05113 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
217 Nebicapone 1件: Nebicapone---1件: 6
218 Nelotanserin 1件: Nelotanserin1件: D09645 1件: HTR2A 💬5件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6
219 Neridronic Acid 1件: Neridronic Acid---1件: 6
220 Niacin 2件: Niacin; Nicotinic acid1件: D00049 --3件: 6, 78, 79
221 Nicotinamide 3件: Multivitamin; Niacinamide; Nicotinamide1件: D00036 --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
222 Nicotinamide riboside 1件: Nicotinamide Riboside---5件: 2, 6, 18, 97, 191
223 Nicotine 2件: NICOTINE; Nicotine gum1件: D03365 16件: CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬		8件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬3件: 6, 13, 84
224 Nilotinib 2件: Nilotinib; Tasigna1件: D08953 4件: ABL1,
KIT,
PDGFRA,
PDGFRB 💬		33件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬5件: 6, 8, 34, 51, 86
225 Nitisinone 2件: NITISINONE; Orfadin1件: D05177 1件: HPD 💬5件: Biosynthesis of cofactors, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬3件: 6, 164, 241
226 Nitric Oxide 3件: INOmax; Nitric Oxide; Nitrosyl1件: D00074 --12件: 6, 58, 85, 86, 88, 97, 210, 222, 251, 294, 299, 321
227 Nitrogen 1件: Nitrogen1件: D00083 --5件: 5, 6, 17, 211, 299
228 Nortriptyline 2件: Nortriptyline; Nortriptyline hydrochloride1件: D08288 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226
229 Omeprazole 4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: D00455 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
230 Ondansetron 1件: Ondansetron1件: D00456 5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		2件: Serotonergic synapse, Taste transduction 💬3件: 6, 97, 107
231 Opicapone 2件: Ongentys; OPICAPONE1件: D10825 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬1件: 6
232 Oxaloacetic acid 1件: Oxaloacetate---2件: 6, 11
233 Oxybuprocaine 1件: Oxybuprocaine1件: D08319 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6
234 Oxybutynin 1件: Oxybutynin1件: D00465 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53
235 Oxycodone 2件: Oxycodone; OXYCODONE HYDROCHLORIDE1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 13, 70, 226, 298
236 Oxygen 3件: Medical air; Nitrogen; Oxygen1件: D00003 --13件: 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
237 Oxytocin 2件: Oxytocin; Syntocinon1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬7件: 6, 72, 127, 168, 193, 206, 226
238 Pardoprunox 1件: Pardoprunox1件: D09397 3件: DRD2,
DRD3,
HTR1A 💬		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
239 Paroxetine 1件: Paroxetine1件: D02362 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 85
240 Perampanel 2件: Fycompa; Perampanel1件: D08964 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬3件: 2, 6, 144
241 Pergolide 1件: PERGOLIDE1件: D08339 2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
242 Phenelzine 1件: Nardil1件: D08349 2件: MAOA,
MAOB 💬		14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
243 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
244 Phosphate ion 1件: Phosphate---32件: 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
245 Piclozotan 1件: Piclozotan---1件: 6
246 Pilocarpine 2件: Pilocarpine; Pilocarpine Hydrochloride1件: D00525 2件: CHRM2,
CHRM3 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 53, 299
247 Pimavanserin 1件: Pimavanserin---1件: 6
248 Pioglitazone 1件: Pioglitazone1件: D08378 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
249 Piribedil 1件: Piribedil1件: D07305 2件: DRD2,
DRD3 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
250 Pitolisant 1件: Pitolisant1件: D10749 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193
251 Plantago seed 2件: Psyllium; Psyllium husk1件: D05525 --3件: 6, 28, 97
252 Polyethylene glycol 4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 33501件: D03370 --17件: 6, 13, 41, 46, 60, 65, 78, 96, 97, 140, 144, 235, 240, 246, 276, 299, 337
253 Posiphen 1件: Posiphen---1件: 6
254 Potassium carbonate 0件: 1件: D02038 --3件: 6, 96, 291
255 Pramipexole 7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL1件: D05575 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
256 Prasinezumab 1件: Prasinezumab1件: D11420 1件: SNCA 💬3件: Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 6
257 Preladenant 1件: Preladenant1件: D09717 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
258 Pridopidine 1件: Pridopidine1件: D09953 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 8
259 Propanoic acid 1件: Propanoic acid---2件: 6, 271
260 Propofol 2件: Propofol; Propofol Injection1件: D00549 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
261 Propranolol 2件: Propanolol; Propranolol1件: D08443 3件: ADRB1,
ADRB2,
ADRB3 💬		12件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 158, 167, 227, 278, 296
262 Psilocybin 2件: Psilocybin; Psilocybine---1件: 6
263 Pyridostigmine 3件: Mestinon; PYRIDOSTIGMINE; PYRIDOSTIGMINE BROMIDE---4件: 3, 6, 11, 256
264 Pyridoxine 2件: PYRIDOXINE; Vitamin B61件: D08454 --5件: 6, 93, 145, 206, 320
265 Pyrimethamine 2件: Daraprim; Pyrimethamine1件: D00488 --12件: 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265
266 Quetiapine 2件: Quetiapine; Seroquel1件: D08456 2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬2件: 6, 13
267 Quinine 0件: 2件: D08460 ,
D08461 		--1件: 6
268 Raclopride 1件: Raclopride---4件: 5, 6, 7, 17
269 Radotinib 1件: Radotinib---1件: 6
270 Ramelteon 2件: Ramelteon; ROZEREM1件: D02689 2件: MTNR1A,
MTNR1B 💬		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬3件: 6, 8, 46
271 Rasagiline 4件: Azilect; Rasagilina; Rasagiline; Rasagiline mesylate2件: D08469 ,
D10829 		1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬6件: 2, 5, 6, 17, 58, 66
272 Remifentanil 2件: Remifentanil; Remifentanyl1件: D08473 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 6, 70
273 Repaglinide 1件: Repaglinide1件: D00594 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬4件: 6, 21, 46, 299
274 Reynoutria multiflora root 1件: Heshouwu---1件: 6
275 Rifampicin 2件: Rifampicin; Rifampin1件: D00211 --9件: 6, 13, 17, 46, 84, 86, 93, 299, 338
276 Rifaximin 3件: RIFAXIMIN; RIFAXIMINA; Xifaxan1件: D02554 --9件: 6, 65, 93, 94, 96, 97, 99, 296, 299
277 Rivastigmine 3件: Exelon; Rivastigmine; Rivastigmine Transdermal System1件: D03822 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬3件: 5, 6, 13
278 Ropinirole 3件: REQUIP; Ropinirole; Ropinirole Hydrochloride1件: D08489 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 2, 6, 74, 309
279 Rosuvastatin 3件: Crestor; Rosuvastatin; Rosuvastatin calcium1件: D08492 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
280 Rotigotine 3件: NEUPRO; ROTIGOTINA; ROTIGOTINE1件: D05768 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
281 Safinamide 3件: Safinamida; SAFINAMIDE; Xadago1件: D10158 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17
282 Sage 1件: Sage---1件: 6
283 Saracatinib 1件: Saracatinib1件: D09664 2件: ABL1,
SRC 💬		49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬3件: 6, 89, 272
284 Sarcosine 1件: Sarcosine---1件: 6
285 Sargramostim 2件: Leukine; Sargramostim1件: D05803 1件: CSF2RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬7件: 6, 28, 60, 62, 96, 229, 285
286 Sarizotan 1件: SARIZOTAN---2件: 6, 156
287 Selegiline 2件: SELEGILINE; Zelapar1件: D03731 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
288 Semaglutide 1件: Semaglutide1件: D10025 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6
289 SEP-363856 1件: SEP-363856---1件: 6
290 Serine 2件: L-Serine; Serine1件: D00016 --4件: 2, 6, 86, 96
291 Sertraline 1件: Sertraline1件: D02360 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206
292 Sevoflurane 1件: Sevoflurane1件: D00547 --7件: 6, 21, 22, 34, 98, 225, 296
293 Sildenafil 6件: Mysildecard; Revatio; Sildenafil; Sildenafil citrate; SILDENAFILO; Viagra1件: D08514 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
294 Silodosin 2件: Silodosin; Silodyx1件: D01965 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 6, 13
295 Simvastatin 3件: Simvastatin; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
296 Sitagliptin 1件: Sitagliptin1件: D08516 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299
297 Smilagenin 1件: SMILAGENIN---1件: 6
298 Sodium chloride 6件: Lactated Ringers; Natriumchlorid; REBIF; SALINE; Sodium chloride; Sporanox1件: D02056 --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
299 Sodium oxybate 1件: Sodium Oxybate1件: D05866 --2件: 6, 149
300 Solifenacin 2件: Solifenacin; Solifenacin Succinate1件: D08522 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬3件: 6, 13, 53
301 Spheramine 1件: Spheramine---1件: 6
302 ST-36 0件: ---2件: 6, 49
303 Sulfachlorpyridazine 0件: 1件: D05948 --1件: 6
304 Sulfanilamide 0件: 1件: D08543 --4件: 6, 30, 60, 298
305 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299
306 Sulforaphane 1件: Sulforaphane---2件: 6, 205
307 Sulpiride 0件: 1件: D01226 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 70
308 Sumanirole 1件: Sumanirole---1件: 6
309 Suvorexant 1件: Suvorexant1件: D10082 2件: HCRTR1,
HCRTR2 💬		1件: Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13
310 Tacrolimus 2件: Prograf; Tacrolimus2件: D00107 ,
D08556 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
311 Tadalafil 4件: Adcirca; CIALIS; Tadalafil; TADALAFILO1件: D02008 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210
312 Talampanel 1件: Talampanel1件: D02696 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬2件: 2, 6
313 Tavapadon 2件: PF-06649751; TAVAPADON1件: D11431 2件: DRD1,
DRD5 💬		10件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬1件: 6
314 Technetium Tc-99m exametazime 1件: Ceretec---1件: 6
315 Terazosin 1件: Terazosin1件: D08569 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6
316 Tesofensine 1件: TESOFENSINE---2件: 6, 193
317 Tolcapone 3件: Tasmar; Tolcapon; Tolcapone1件: D00786 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127
318 Topiramate 2件: TOPAMAX; Topiramate1件: D00537 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193
319 Tozadenant 1件: TOZADENANT1件: D10174 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
320 Trehalose 2件: Cabaletta; Trehalose---4件: 2, 6, 18, 113
321 Tributyrin 1件: Tributyrin---1件: 6
322 Trihexyphenidyl 1件: Trihexyphenidyl1件: D08638 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
323 Trimethobenzamide 3件: Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride1件: D08643 --1件: 6
324 Tropicamide 1件: Tropicamide1件: D00397 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6
325 Tryptophan 2件: Propanoic acid; Tryptophan1件: D00020 --2件: 6, 75
326 Tulobuterol 1件: Tulobuterol1件: D02151 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
327 Tyrosine 4件: Alanine; L-tyrosine; Propanoic acid; Tyrosine1件: D00022 --5件: 6, 75, 86, 111, 298
328 Ubidecarenone 3件: Coenzyme Q-10; Coenzyme Q10; CoQ101件: D01065 --12件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215
329 Ubiquinol 1件: Ubiquinol---3件: 6, 8, 17
330 Uric acid 1件: Urate---1件: 6
331 Ursodeoxycholic acid 4件: UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
332 Valerian 1件: Valerian---1件: 6
333 Valiloxybate 1件: Valiloxybate1件: D12240 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬1件: 6
334 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬14件: 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
335 Varenicline 2件: Champix; Varenicline1件: D08669 2件: CHRNA4,
CHRNB2 💬		4件: Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬3件: 6, 18, 53
336 Venglustat 2件: GENZ-682452; Venglustat1件: D11633 1件: UGCG 💬2件: Metabolic pathways, Sphingolipid metabolism 💬3件: 6, 19, 67
337 Venlafaxine 2件: Venlafaxine; VENLAFAXINE HYDROCHLORIDE1件: D08670 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 6, 13, 46
338 Vitamin E 2件: Alpha-tocopherol; Vitamin E1件: D02331 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
339 Vortioxetine 1件: Vortioxetine1件: D10184 7件: HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬		5件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬1件: 6
340 Warfarin 2件: Warfarin; Warfarin Sodium1件: D08682 2件: NQO1,
VKORC1 💬		7件: Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
341 Water 8件: AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: D00001 --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
342 Wheat 1件: Wheat1件: D06902 --2件: 6, 53
343 Wheat bran 1件: Wheat bran---1件: 6
344 Yohimbine 1件: Yohimbine1件: D08685 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 6
345 Zoledronic acid 4件: ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa2件: D01968 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
346 Zolmitriptan 1件: Zolmitriptan1件: D00415 2件: HTR1B,
HTR1D 💬		4件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
347 Zolpidem 2件: Zolpidem; Zolpidem Tartrate1件: D08690 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 5, 6, 46
348 Zonisamide 2件: Zonegran; Zonisamide1件: D00538 8件: CACNA1G,
CACNA1H,
CACNA1I,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		11件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus 💬1件: 6
349 Zopiclone 1件: Zopiclone1件: D01372 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6