76. 下垂体性ゴナドトロピン分泌亢進症 Pituitary gonadotropin secretion hyperthyroidism Clinical trials / Disease details

臨床試験数 : 29 / 薬物数 : 44 - (DrugBank : 14) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 15

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05341115 (ClinicalTrials.gov)	March 20, 2023	18/4/2022	A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty	An Open Label, Multicenter, Single-arm and Prospective Study to Assess the Efficacy and Safety of Le ...	Central Precocious Puberty	Drug: Leuprorelin Acetate Depot 3M	Takeda	NULL	Not yet recruiting	N/A	9 Years	All	80	Phase 4	China
2	ChiCTR2100054310	2021-12-13	2021-12-13	Diagnostic significance of random urinary gonadotropin levels in girls with central precocious puber ...	Diagnostic significance of random urinary gonadotropin levels in girls with central precocious puber ...	precocious puberty	GoldStandard:Randomized urinary gonadotropin levels;Index test:Gonadotropin-releasing hormone challe ...	Children's Hospital Affiliated to Zhejiang University School of Medicine	NULL	Pending	4	10	Both	Target condition:60;Difficult condition:40	N/A	China
3	NCT05029622 (ClinicalTrials.gov)	August 10, 2021	9/8/2021	A Study to Assess the Efficacy and Safety of the Triptorelin 6-month Formulation in Paediatric Parti ...	A Phase III, Open-label, Multicentre, Single Arm Study to Assess the Efficacy and Safety of the Trip ...	Central Precocious Puberty	Drug: Triptorelin Pamoate	Ipsen	NULL	Completed	N/A	10 Years	All	66	Phase 3	China
4	NCT04736602 (ClinicalTrials.gov)	March 27, 2021	29/1/2021	Efficacy and Safety Study of Triptorelin 3-Month Formulation in Chinese Children With Central Precoc ...	An Open-label, Multicentre, Single Arm Study to Assess the Efficacy and Safety of Triptorelin 3-mont ...	Central Precocious Puberty	Drug: Triptorelin pamoate 15mg	Ipsen	NULL	Completed	N/A	10 Years	All	32	Phase 3	China
5	ChiCTR2100047299	2020-12-01	2021-06-12	The use of morning urinary gonadotropins and sexual hormones in the diagnosis and monitoring treatme ...	The use of morning urinary gonadotropins and sexual hormones in the diagnosis and monitoring treatme ...	precocious puberty	GoldStandard:gonadotropin releasing hormone stimulation test ;Index test:luteinizing hormone, follic ...	The Children's Hospital, Zhejiang University School of Medicine	NULL	Recruiting	3	10	Female	Target condition:200;Difficult condition:100		China
6	ChiCTR2000038202	2020-09-01	2020-09-13	AMH combined INHB for the diagnosis of female central precocious puberty	AMH combined INHB for the diagnosis of female central precocious puberty	Central precocious puberty	Gold Standard:GnRHa provoctive test;Index test:Anti Mullerian hormone, Inhibin B;	Capital Institute of Pediatrics	NULL	Recruiting	5	8	Female	Target condition:150;Difficult condition:150		China
7	ChiCTR2000034464	2020-09-01	2020-07-05	First Morning Voided Urinary Gonadotropin Measurements for the Early Screening, Diagnosis and Follow ...	First Morning Voided Urinary Gonadotropin Measurements for the Early Screening, Diagnosis and Follow ...	Central precocious puberty	Gold Standard:Clinical outcome by CPP diagnostic standards;Index test:morning urine GN;	Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science ...	NULL	Pending	6	12	Both	Target condition:400;Difficult condition:6000		China
8	NCT03963752 (ClinicalTrials.gov)	August 15, 2019	22/5/2019	Clinical Trial of Rapid Progressive Central Precocious PubertyWith Integrative Chinese and Western M ...	Evidence-based Medical Research on the Treatment of Children's Rapid Progressive Central Precocious ...	Idiopathic Precocious Puberty	Drug: Ziyinxiehuo Granules Herbs;Drug: Megestrol Acetate Tablet;Drug: Leuprorelin Acetate 3.75mg Injec ...	Children's Hospital of Fudan University	NULL	Recruiting	5 Years	8 Years	Female	164	Phase 4	China
9	NCT03695237 (ClinicalTrials.gov)	October 24, 2018	2/10/2018	A Study to Evaluate Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Leuprolide Acetate 4 ...	A Phase 3, Multicenter, Open-Label, Two-Part Study to Evaluate the Safety, Efficacy, Pharmacokinetic ...	Central Precocious Puberty (CPP)	Drug: Leuprolide Acetate (LA)	AbbVie	NULL	Active, not recruiting	2 Years	11 Years	All	45	Phase 3	United States;Puerto Rico
10	ChiCTR1800017120	2018-08-01	2018-07-12	A real world study for the efficacy and safety of the combination therapy of GnRHa and recombinant h ...	A real world study for the efficacy and safety of the combination therapy of GnRHa and recombinant h ...	precocious puberty	Case series:rhGH therapy;	The Children's Hospital, Zhejiang University School of Medicine	NULL	Recruiting	3	12	Female	Case series:700;		China

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