OGT 918 ( DrugBank: - )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
19ライソゾーム病2
299嚢胞性線維症2

19. ライソゾーム病


臨床試験数 : 899 薬物数 : 684 - (DrugBank : 99) / 標的遺伝子数 : 51 - 標的パスウェイ数 : 182
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00316498
(ClinicalTrials.gov)
October 17, 200219/4/2006Saccadic Eye Movements in Patients With Niemann-Pick Type C DiseaseA Phase I/II Randomized, Controlled Study of OGT 918 in Adult and Juvenile Patients With Niemann Pick C DiseaseNiemann Pick DiseasesDrug: OGT918National Eye Institute (NEI)NULLCompleted12 YearsN/AAll30Phase 1United States;United Kingdom
2NCT00041535
(ClinicalTrials.gov)
July 5, 20029/7/2002OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher DiseaseA Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher DiseaseGaucher DiseaseDrug: OGT 918National Institute of Neurological Disorders and Stroke (NINDS)NULLCompleted4 YearsN/AAll30Phase 2United States;United Kingdom

299. 嚢胞性線維症


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00537602
(ClinicalTrials.gov)
November 200728/9/2007Miglustat / OGT 918 in the Treatment of Cystic FibrosisSingle Center, Double-blind, Randomized, Placebo-controlled, 2-period/2-treatment Crossover Study Investigating the Effect of Miglustat on the Nasal Potential Difference in Patients With Cystic Fibrosis Homozygous for the ?F508 MutationCystic FibrosisDrug: miglustat;Drug: placeboActelionNULLTerminated12 YearsN/ABoth6Phase 2Spain
2EUCTR2006-002049-35-ES
(EUCTR)
22/07/200728/05/2007Estudio unicéntrico, a doble ciego, aleatorizado y controlado con placebo, cruzado de 2 brazos, para investigar el efecto de miglustat sobre la diferencia de potencial nasal en pacientes con fibrosis quística homocigotos para la mutación ?F508Estudio unicéntrico, a doble ciego, aleatorizado y controlado con placebo, cruzado de 2 brazos, para investigar el efecto de miglustat sobre la diferencia de potencial nasal en pacientes con fibrosis quística homocigotos para la mutación ?F508 fibrosis quística
MedDRA version: 8.1;Level: LLT;Classification code 10011762;Term: Cystic fibrosis
Trade Name: Zavesca
Product Name: miglustat
Product Code: OGT 918
INN or Proposed INN: Miglustat
Other descriptive name: 1,5 (Butylimino)-1,5-dideoxy-D-glucitol
Actelion Pharmaceuticals LtdNULLNot RecruitingFemale: yes
Male: yes
25Phase 2Spain