TAMOXIFEN ( DrugBank: Tamoxifen )

3 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
2	筋萎縮性側索硬化症	3
113	筋ジストロフィー	7
227	オスラー病	1

2. 筋萎縮性側索硬化症

臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02166944 (ClinicalTrials.gov)	April 2014	9/6/2014	Tamoxifen Treatment in Patients With Motor Neuron Disease	The Study of Tamoxifen Treatment in Patients With Motor Neuron Disease	Amyotrophic Lateral Sclerosis;ALS Functional Ration Scale;TAR-DNA-binding Protein-43;Tamoxifen;mTOR	Drug: tamoxifen 40 mg daily for one year	Taipei Medical University Shuang Ho Hospital	NULL	Completed	20 Years	80 Years	All	20	Phase 1/Phase 2	Taiwan
2	NCT01257581 (ClinicalTrials.gov)	March 2011	8/12/2010	Safety and Efficacy Study of Creatine and Tamoxifenin Volunteers With Amyotrophic Lateral Sclerosis ...	Phase 2 Selection Trial of High Dosage Creatine and Two Dosages of Tamoxifenin Amyotrophic Lateral S ...	Amyotrophic Lateral Sclerosis	Drug: creatine;Drug: tamoxifen	Nazem Atassi	ALS Therapy Alliance;State University of New York - Upstate Medical University	Completed	18 Years	N/A	All	60	Phase 2	United States
3	NCT00214110 (ClinicalTrials.gov)	January 2001	13/9/2005	Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS]	Phase 2 Randomized Single-blind Escalating Dose Response Clinical Trial of TamoxifenTherapy on Mean ...	Amyotrophic Lateral Sclerosis (ALS)	Drug: Tamoxifen	University of Wisconsin, Madison	NULL	Completed	18 Years	90 Years	Both	100	Phase 2	United States

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113. 筋ジストロフィー

臨床試験数 : 646 / 薬物数 : 471 - (DrugBank : 105) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 170

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2017-004554-42-FR (EUCTR)	26/03/2020	17/08/2018	The study examines boys suffering from Duchenne muscular dystrophy. We are carrying out this study t ...	Tamoxifenin Duchenne muscular dystrophy - TAMDMDA multicentre, randomised, double-blind, placebo-con ...	Duchenne muscular dystrophy MedDRA version: 20.0;Level: PT;Classification code 10013801;Term: Duchen ...	Trade Name: Tamoxifen20mg Hexal® Filmtabletten INN or Proposed INN: Tamoxifen Other descriptive name: ...	University of Basel Children's Hospital, Division of Neuropediatrics	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: yes	100	Phase 3	France;Belgium;Spain;Turkey;Netherlands;Germany;United Kingdom;Switzerland
2	EUCTR2017-004554-42-GB (EUCTR)	29/01/2019	03/08/2018	The study examines boys suffering from Duchenne muscular dystrophy. We are carrying out this study t ...	Tamoxifenin Duchenne muscular dystrophy - TAMDMDA multicentre, randomised, double-blind, placebo-con ...	Duchenne muscular dystrophy MedDRA version: 20.0;Level: PT;Classification code 10013801;Term: Duchen ...	Trade Name: Tamoxifen20mg Hexal® Filmtabletten INN or Proposed INN: Tamoxifen Other descriptive name: ...	University of Basel Children's Hospital, Division of Neuropediatrics	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: yes	100	Phase 3	France;Belgium;Spain;Netherlands;Germany;Switzerland;United Kingdom
3	EUCTR2017-004554-42-ES (EUCTR)	22/01/2019	17/09/2018	The study examines boys suffering from Duchenne muscular dystrophy. We are carrying out this study t ...	Tamoxifenin Duchenne muscular dystrophy - TAMDMD A multicentre, randomised, double-blind, placebo-c ...	Duchenne muscular dystrophy MedDRA version: 20.0;Level: PT;Classification code 10013801;Term: Duchen ...	Trade Name: TAMOX INN or Proposed INN: Tamoxifen Other descriptive name: TAMOXIFEN CITRATE	University of Basel Children's Hospital, Division of Neuropediatrics	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: yes	100	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	France;Belgium;Spain;Turkey;Netherlands;Germany;United Kingdom;Switzerland
4	EUCTR2017-004554-42-NL (EUCTR)	16/01/2019	02/10/2018	The study examines boys suffering from Duchenne muscular dystrophy. We are carrying out this study t ...	Tamoxifenin Duchenne muscular dystrophy - TAMDMDA multicentre, randomised, double-blind, placebo-con ...	Duchenne muscular dystrophy MedDRA version: 20.0;Level: PT;Classification code 10013801;Term: Duchen ...	Trade Name: TAMOXIFEN INN or Proposed INN: Tamoxifen Other descriptive name: TAMOXIFEN CITRATE	University of Basel Children's Hospital, Division of Neuropediatrics	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: yes	100	Phase 3	France;Belgium;Spain;Turkey;Germany;Netherlands;United Kingdom;Switzerland
5	NCT03354039 (ClinicalTrials.gov)	June 12, 2018	10/10/2017	Tamoxifen in Duchenne Muscular Dystrophy	Tamoxifenin Duchenne Muscular Dystrophy: A Multicenter, Randomised, Double-blind, Placebo-controlled ...	Duchenne Muscular Dystrophy	Drug: Tamoxifen;Drug: Matching placebo	University Hospital, Basel, Switzerland	NULL	Completed	78 Months	16 Years	Male	93	Phase 3	France;Germany;Netherlands;Spain;Switzerland;United Kingdom
6	EUCTR2017-004554-42-DE (EUCTR)		27/07/2018	The study examines boys suffering from Duchenne muscular dystrophy. We are carrying out this study t ...	Tamoxifenin Duchenne muscular dystrophy: A multicenter, randomised, double-blind, placebo-controlle ...	Duchenne muscular dystrophy MedDRA version: 20.0;Level: PT;Classification code 10013801;Term: Duchen ...	Trade Name: Tamoxifen20mg Hexal® Filmtabletten INN or Proposed INN: Tamoxifen Other descriptive name: ...	University of Basel Children's Hospital, Division of Neuropediatrics	NULL	NA			Female: no Male: yes	100	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	France;Belgium;Spain;Turkey;Netherlands;Germany;United Kingdom;Switzerland
7	EUCTR2017-004554-42-BE (EUCTR)		30/04/2019	The study examines boys suffering from Duchenne muscular dystrophy. We are carrying out this study t ...	Tamoxifenin Duchenne muscular dystrophy:A multicenter, randomised, double-blind, placebo-controlled, ...	Duchenne muscular dystrophy MedDRA version: 20.0;Level: PT;Classification code 10013801;Term: Duchen ...	Trade Name: Tamoxifen20mg Hexal® Filmtabletten INN or Proposed INN: Tamoxifen Other descriptive name: ...	University of Basel Children's Hospital, Division of Neuropediatrics	NULL	NA			Female: no Male: yes	100	Phase 3	France;Spain;Belgium;Turkey;Netherlands;Germany;United Kingdom;Switzerland

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227. オスラー病

臨床試験数 : 56 / 薬物数 : 72 - (DrugBank : 21) / 標的遺伝子数 : 23 - 標的パスウェイ数 : 136

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00375622 (ClinicalTrials.gov)	February 2005	12/9/2006	Anti-Estrogen Therapy for Hereditary Hemorrhagic Telangiectasia A Double-Blind Placebo-Controlled Cl ...		Hereditary Hemorrhagic Telangiectasia	Drug: Tamoxifen	Rabin Medical Center	NULL	Completed	18 Years	N/A	Both	60	Phase 2	Israel

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