Butylphthalide ( DrugBank: Butylphthalide )

4 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
2	筋萎縮性側索硬化症	1
6	パーキンソン病	3
18	脊髄小脳変性症（多系統萎縮症を除く。）	1
22	もやもや病	1

2. 筋萎縮性側索硬化症

臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR-IPR-15007365	2015-11-04	2015-11-03	A Multi-center, Randomized, Double Blinding, Placebo-Controlled Clinical Trial of Dl-3-Butylphthalid ...	A Multi-center, Randomized, Double Blinding, Placebo-Controlled Clinical Trial of Dl-3-Butylphthalid ...	amyotrophic lateral sclerosis	Treatment group:to give Butylphthalidesoft capsules, 2 / time, 3 times / day, fasting;Control group: ...	Peking Union Medical College Hospital	NULL	Recruiting			Both	Treatment group:147;Control group:147;		China

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6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR1900023725	2019-08-01	2019-06-09	Study for the Role of Butylphthalidein Delaying the progression of Parkinson's disease (PD), Vascula ...	Study for the Role of Butylphthalidein Delaying the progression of Parkinson's disease (PD), Vascula ...	Parkinson's disease (PD), Vascular Parkinson's disease (VP) and Parkinsonism-plus syndrome (PPS)	PD-Placebo:Placebo;PD-Butylphthalide:Butylphthalide;VP-Placebo:Placebo;VP-Butylphthalide:Butylphthal ...	Zhujiang Hospital of Southern Medical University	NULL	Pending	18	80	Male	PD-Placebo:50;PD-Butylphthalide:50;VP-Placebo:50;VP-Butylphthalide:50;MSA-Placebo:50;MSA-Butylphthalide :50;PSP-Placebo:50;PSP-Butylphthalide:50;		China
2	ChiCTR1800017084	2018-08-01	2018-07-11	Investigation of new approaches and technologies in the management of Parkinson's disease	The efficacy of Butylphthalideon cognitive impairment of patients with idiopathic PD and DBS patient ...	Parkinson's disease	Butylphthalidegroup:Butylphthalide, 2 capsules/time, 3 times/day, for 48 weeks;Control group:Placebo ...	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	NULL	Recruiting	18	80	Both	Butylphthalide group:140;Control group:140;	Phase 4	China
3	ChiCTR-IPR-16009395	2016-11-01	2016-10-14	Clinical trial on efficacy and safety of add-on treatment of Butylphthalidein patients with Parkinso ...	Clinical trial on efficacy and safety of add-on treatment of Butylphthalidein patients with Parkinso ...	Parkinson’s disease	Butylphthalidegroup and Control group:Butylphthalide200mg/time(2 capsules) , three time/day, for 24 ...	The Second Affiliated Hospital of Soochow University	NULL	Pending	35		Both	Butylphthalide group and Control group:36;Control:36;		China

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18. 脊髄小脳変性症（多系統萎縮症を除く。）

臨床試験数 : 76 / 薬物数 : 98 - (DrugBank : 31) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 65

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR-IIR-17012717	2017-09-20	2017-09-18	Treatment of SCA3/MJD patients with oral DL-3-n-butylphthalide: A randomized, double blind, placebo ...	Treatment of SCA3/MJD patients with oral DL-3-n-butylphthalide: A randomized, double blind, placebo ...	SCA3/MJD	Test group:DL-3-n-butylphthalide;Control group:Placebo;	Xiangya Hospital of Central South University	NULL	Recruiting	10	60	Both	Test group:60;Control group:60;	2 (Phase 2 study)	China

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22. もやもや病

臨床試験数 : 17 / 薬物数 : 22 - (DrugBank : 17) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 45

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04205578 (ClinicalTrials.gov)	January 2020	18/12/2019	NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events	A Multi-center, Randomized, Single-blind, Placebo-controlled Study of Dl-3-n-butylphthalidein Patien ...	Moyamoya Disease;Ischemic Cerebral Infarction;Ischemic Stroke;Ischemic Cerebrovascular Accident;Tran ...	Drug: dl-3-n-butylphthalide (NBP);Drug: Normal Saline 0.9% Infusion Solution	yuanli Zhao	Peking University International Hospital	Not yet recruiting	18 Years	60 Years	All	450	Phase 3	China

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