Chenodeoxycholic Acid ( DrugBank: Chenodeoxycholic acid )

4 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
20	副腎白質ジストロフィー	1
96	クローン病	1
234	ペルオキシソーム病（副腎白質ジストロフィーを除く。）	1
263	脳腱黄色腫症	4

20. 副腎白質ジストロフィー

臨床試験数 : 61 / 薬物数 : 90 - (DrugBank : 31) / 標的遺伝子数 : 23 - 標的パスウェイ数 : 126

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00004442 (ClinicalTrials.gov)	September 1997	18/10/1999	Study of Bile Acids in Patients With Peroxisomal Disorders		Infantile Refsum's Disease;Zellweger Syndrome;Bifunctional Enzyme Deficiency;Adrenoleukodystrophy	Drug: chenodeoxycholic acid;Drug: cholic acid;Drug: ursodiol	Children's Hospital Research Foundation University of Cincinnati	Children's Hospital Medical Center, Cincinnati	Terminated	N/A	5 Years	Both	25	N/A	NULL

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96. クローン病

臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2009-013348-35-NL (EUCTR)	04/08/2009	03/07/2009	(Patho)Physiological aspects of the bile salt-FXR-FGF19-axis: potential consequences in Crohn's dise ...	(Patho)Physiological aspects of the bile salt-FXR-FGF19-axis: potential consequences in Crohn's dise ...	Patients with quiescent Crohn’s colitis, defined as a Crohn’s Disease Activity Index <150 ; non-IBD ...	Trade Name: Chenofalk Product Name: Chenofalk Product Code: RVG 07151 INN or Proposed INN: CHENODEOXYCH ...	University Medical Center Utrecht	NULL	Not Recruiting			Female: yes Male: yes			Netherlands

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234. ペルオキシソーム病（副腎白質ジストロフィーを除く。）

臨床試験数 : 39 / 薬物数 : 35 - (DrugBank : 12) / 標的遺伝子数 : 13 - 標的パスウェイ数 : 45

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00004442 (ClinicalTrials.gov)	September 1997	18/10/1999	Study of Bile Acids in Patients With Peroxisomal Disorders		Infantile Refsum's Disease;Zellweger Syndrome;Bifunctional Enzyme Deficiency;Adrenoleukodystrophy	Drug: chenodeoxycholic acid;Drug: cholic acid;Drug: ursodiol	Children's Hospital Research Foundation University of Cincinnati	Children's Hospital Medical Center, Cincinnati	Terminated	N/A	5 Years	Both	25	N/A	NULL

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263. 脳腱黄色腫症

臨床試験数 : 6 / 薬物数 : 11 - (DrugBank : 2) / 標的遺伝子数 : 2 - 標的パスウェイ数 : 4

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-JapicCTI-205157	03/8/2020	13/02/2020	An open-label study of FPF1011 in patients with cerebrotendinous xanthomatosis (phase 3)	An open-label study of FPF1011 in patients with cerebrotendinous xanthomatosis (phase 3)	Cerebrotendinous xanthomatosis	Intervention name : FPF1011 INN of the intervention : Chenodeoxycholic acid Dosage And administration ...	Fujimoto Pharmaceutical Corporation	NULL	recruiting	0		BOTH	5	Phase 3	Japan
2	NCT04270682 (ClinicalTrials.gov)	January 31, 2020	12/2/2020	Study to Evaluate Patients With Cerebrotendinous Xanthomatosis (RESTORE)	A Phase 3 Study to Evaluate the Effects of Chenodeoxycholic Acidin Adult and Pediatric Patients With ...	CTX	Drug: Blinded CDCA 250 mg TID;Drug: Placebo;Drug: Open-Label CDCA 250 mg TID;Drug: Rescue Medication ...	Travere Therapeutics, Inc.	NULL	Recruiting	1 Month	N/A	All	12	Phase 3	United States;Brazil
3	NCT00018694 (ClinicalTrials.gov)	October 1999	3/7/2001	Cholestanol in Humans	Biologic Significance of Cholestanol in Man	Cerebrotendinous Xanthomatosis	Drug: Chenodeoxycholic Acid	Department of Veterans Affairs	NULL	Withdrawn	5 Years	80 Years	Both	0	N/A	United States
4	NCT00004346 (ClinicalTrials.gov)	January 1996	18/10/1999	Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acidfor C ...	Effects of Diet and Medication in Patients With Cerebrotendinous Xanthomatosis (CTX)	Cerebrotendinous Xanthomatosis	Drug: chenodeoxycholic acid;Drug: lovastatin	National Center for Research Resources (NCRR)	Oregon Health and Science University	Recruiting	N/A	N/A	Both	5	Phase 2	United States

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