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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
15-[4-[2-(5-(1-hydroxyethyl)-2- pyridinyl)ethoxy]benzyl]-2,4- thiazolidinedione hydrochloride1件: 2,4-thiazolidinedione---1件: 20
25-[4-[2-(5-(1-hydroxyethyl)-2-pyridinyl)ethoxy]benzyl]-2,4-thiazolidinedione hydrochloride1件: 2,4-thiazolidinedione---1件: 20
35-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY]PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE HYDROCHLORIDE1件: 2,4-thiazolidinedione---1件: 20
4Acetylcysteine1件: Acetylcysteine1件: D00221 --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
5Albumin----3件: 2, 20, 51
6Albumin solution----1件: 20
7Albunorm® 5%,----1件: 20
8ALEMTUZUMAB1件: Alemtuzumab1件: D02802 1件: CD52 💬-17件: 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284
9Allo-HSCT----1件: 20
10AUTOLOGOUS CD34+ CELLS TRANSDUCED WITH LENTI-D VECTOR ENCODING ABCD1 CDNA----1件: 20
11Autologous haematopoietic stem cells transduced with lentiviral vector Lenti-D encoding the human ABCD1 cDNA----1件: 20
12Bezafibrate1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324
13BIOTIN1件: Biotin1件: D00029 --5件: 2, 8, 10, 13, 20
14Busulfan1件: Busulfan1件: D00248 --13件: 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
15Busulfan, Cyclophosphamide, Antithymocyte Globulin2件: Busulfan,
Cyclophosphamide		3件: D00248 ,
D00287 ,
D07760 		--2件: 19, 20
16CALD HR-D (High-Risk, Regimen C)----5件: 19, 20, 125, 234, 326
17CALD HR-D (High-Risk, Regimen D)----5件: 19, 20, 125, 234, 326
18CALD SR-A (Standard-Risk, Regimen A)----5件: 19, 20, 125, 234, 326
19CALD SR-B (Standard-Risk, Regimen B)----5件: 19, 20, 125, 234, 326
20Campath1件: Alemtuzumab1件: D02802 1件: CD52 💬-12件: 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326
21Campath-1H1件: Alemtuzumab1件: D02802 1件: CD52 💬-6件: 19, 20, 60, 234, 285, 326
22Chenodeoxycholic acid1件: Chenodeoxycholic acid1件: D00163 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 96, 234, 263
23Cholic Acid1件: Cholic Acid1件: D10699 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 234, 265, 310
24Cholic Acids----2件: 20, 234
25Clofarabine1件: Clofarabine1件: D03546 3件: POLA1,
POLA2,
RRM1 💬		7件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 234, 326
26Cyclophosphamide1件: Cyclophosphamide2件: D00287 ,
D07760 		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
27Cyclosporine1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
28Cyclosporine A1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬11件: 19, 20, 36, 49, 50, 53, 58, 60, 107, 234, 283
29D-BIOTIN1件: Biotin1件: D00029 --3件: 10, 13, 20
30DUOC-01----3件: 13, 19, 20
31Elivaldogene autotemcel1件: Elivaldogene autotemcel1件: D12150 1件: ABCD1 💬2件: ABC transporters, Peroxisome 💬1件: 20
32Elivaldogenum tavalentivecum----1件: 20
33Glyceryl Trierucate1件: Glyceryl Trierucate---1件: 20
34Glyceryl trierucate/glyceryl trioleate2件: Glyceryl Trierucate,
Glyceryl Trioleate		---1件: 20
35Glyceryl Trioleate1件: Glyceryl Trioleate---1件: 20
36Hematopoietic stem cell infusion----2件: 19, 20
37Hematopoietic Stem Cell Transplantation----12件: 11, 13, 14, 19, 20, 35, 46, 49, 51, 96, 234, 285
38Human Placental Derived Stem Cell----4件: 19, 20, 60, 284
39Hydroxyurea1件: Hydroxyurea1件: D00341 1件: RRM2 💬7件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284
40IMD----5件: 19, 20, 125, 234, 326
41IMD Preparative Regimen----5件: 19, 20, 125, 234, 326
42Interferon Beta1件: Human interferon beta---6件: 13, 20, 26, 50, 96, 97
43Intracerebral LV gene therapy----1件: 20
44Lenti-D----1件: 20
45Lenti-D Drug Product----1件: 20
46Leriglitazone1件: Leriglitazone1件: D11603 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 20
47Lipoic acid1件: Lipoic acid---5件: 2, 5, 13, 14, 20
48Lorenzo's Oil----1件: 20
49MD1003----5件: 2, 10, 13, 14, 20
50MD1003 100 mg capsule----1件: 20
51Melphalan1件: Melphalan1件: D00369 --15件: 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
52Mesenchymal stem cells----11件: 2, 6, 13, 20, 49, 51, 60, 96, 222, 274, 299
53MIN-102----2件: 18, 20
54Modified cobratoxin----1件: 20
55Mycophenolate1件: Mycophenolic acid1件: D05096 2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
56Mycophenolate mofetil2件: Mycophenolate mofetil,
Mycophenolic acid		2件: D00752 ,
D05096 		2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
57Mycophenylate mofetil----2件: 19, 20
58N-Acetylcysteine1件: Acetylcysteine1件: D00221 --13件: 6, 13, 19, 20, 21, 49, 58, 85, 90, 111, 164, 299, 337
59NV1205----1件: 20
60Osteopetrosis Haploidentical Only Preparative Regimen----5件: 19, 20, 125, 234, 326
61Osteopetrosis Only Preparative Regimen----5件: 19, 20, 125, 234, 326
62Pioglitazone1件: Pioglitazone1件: D08378 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
63PLERIXAFOR1件: Plerixafor1件: D08971 1件: CXCR4 💬14件: Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬4件: 20, 65, 285, 299
64Pramipexole1件: Pramipexole1件: D05575 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
65PXL065----1件: 20
66PXL770----1件: 20
67QTXEW2-04-AF, EW2, GC-1, QRX-431----1件: 20
68RPI78M for injection----1件: 20
69SBT101----1件: 20
70Sobetirome1件: Sobetirome1件: D09381 1件: THRB 💬2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20
71Sobetirome (NV1205)1件: Sobetirome1件: D09381 1件: THRB 💬2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20
72Stem Cell Transplantation----10件: 13, 19, 20, 46, 65, 90, 125, 164, 234, 326
73Thalidomide1件: Thalidomide1件: D00754 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
74Thiazolidinedione1件: 2,4-thiazolidinedione---1件: 20
75Thiotepa1件: Thiotepa1件: D00583 --12件: 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
76Thiotepa--escalated dose1件: Thiotepa1件: D00583 --4件: 19, 20, 65, 284
77Thiotepa--single daily dose1件: Thiotepa1件: D00583 --4件: 19, 20, 65, 284
78Transduced CD34+ hematopoietic stem cell----2件: 19, 20
79Ursodiol1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬6件: 8, 20, 93, 97, 234, 299
80Vitamin D31件: Cholecalciferol1件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬12件: 6, 13, 20, 46, 49, 51, 53, 60, 65, 96, 97, 299
81Vitamin E1件: Vitamin E1件: D02331 --11件: 2, 6, 13, 20, 46, 90, 96, 97, 206, 299, 317
82VK0214----1件: 20