Interferon alfa ( DrugBank: Interferon alfa )

5 diseases

25. 進行性多巣性白質脳症

臨床試験数 : 26 / 薬物数 : 35 - (DrugBank : 22) / 標的遺伝子数 : 8 - 標的パスウェイ数 : 37

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00002270 (ClinicalTrials.gov)	October 1997	2/11/1999	A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection	A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection	HIV Infections;Leukoencephalopathy, Progressive Multifocal	Drug: Interferon alfa-2b;Drug: Zidovudine	University of Miami	NULL	Completed	18 Years	65 Years	Both		N/A	United States

臨床試験数 : 29 / 薬物数 : 47 - (DrugBank : 29) / 標的遺伝子数 : 34 - 標的パスウェイ数 : 119

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00041327 (ClinicalTrials.gov)	October 2002	8/7/2002	Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma	Phase II Trial Of Induction Therapy With EPOCH Chemotherapy And Maintenance Therapy With Combivir/Interferon ALPHA-2a For HTLV-1 Associated T-Cell Non-Hodgkin's Lymphoma	Lymphoma	Biological: filgrastim;Biological: recombinant interferon alfa;Drug: Etoposide;Drug: cyclophosphamide;Drug: doxorubicin hydrochloride;Drug: lamivudine;Drug: prednisone;Drug: vincristine sulfate;Drug: zidovudine	AIDS Malignancy Consortium	National Cancer Institute (NCI)	Completed	18 Years	120 Years	Both	19	Phase 2	United States

臨床試験数 : 267 / 薬物数 : 241 - (DrugBank : 77) / 標的遺伝子数 : 68 - 標的パスウェイ数 : 180

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00007995 (ClinicalTrials.gov)	July 1999	6/1/2001	Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients Who Have Multiple Myeloma or Primary Systemic Amyloidosis	Phase 2 Study Of High Dose Chemotherapy Followed By Autologous Hematopoietic Stem Cell Support In Patients With Multiple Myeloma And Primary Light Chain Amyloidosis	Multiple Myeloma and Plasma Cell Neoplasm	Biological: filgrastim;Biological: recombinant interferon alfa;Biological: sargramostim;Drug: busulfan;Drug: cyclophosphamide;Drug: melphalan;Procedure: autologous bone marrow transplantation;Procedure: bone marrow ablation with stem cell support;Procedure: peripheral blood stem cell transplantation	Herbert Irving Comprehensive Cancer Center	National Cancer Institute (NCI)	Completed	18 Years	N/A	Both	75	Phase 2	United States
2	NCT00002849 (ClinicalTrials.gov)	November 1996	1/11/1999	S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis	Phase II Study of Dexamethasone/Alpha-Interferon in AL Amyloidosis	Multiple Myeloma	Biological: recombinant interferon alfa;Drug: dexamethasone	Southwest Oncology Group	National Cancer Institute (NCI);Cancer and Leukemia Group B	Completed	18 Years	N/A	Both	93	Phase 2	United States

臨床試験数 : 81 / 薬物数 : 107 - (DrugBank : 30) / 標的遺伝子数 : 36 - 標的パスウェイ数 : 116

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03209219 (ClinicalTrials.gov)	June 30, 2017	4/7/2017	Interferon a2a Versus Cyclosporine for Refractory Behçet's Disease Uveitis	Randomized Prospective Comparative Study of Interferon a2a and Cyclosporine in Patients With Refractory Behçet's Disease Uveitis	Behçet Disease;Uveitis	Drug: Interferon Alfa-2A;Drug: Cyclosporine Pill	Peking Union Medical College Hospital	NULL	Completed	18 Years	65 Years	All	28	Phase 3	China

臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00897312 (ClinicalTrials.gov)	October 2006	9/5/2009	Effect of Biological Therapy on Biomarkers in Patients With Untreated Hepatitis C, Metastatic Melanoma, or Crohn Disease	Title: Evaluation of Systemic IDO Levels After Various Immunotherapeutics	Melanoma	Biological: infliximab;Biological: pegylated interferon alfa;Biological: ticilimumab;Drug: ribavirin;Other: high performance liquid chromatography;Other: laboratory biomarker analysis	Vanderbilt-Ingram Cancer Center	National Cancer Institute (NCI)	Terminated	N/A	N/A	Both	7	N/A	NULL