4-phenylbutyrate ( DrugBank: 4-phenylbutyrate, Phenylbutyrate )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
251	尿素サイクル異常症	1
299	嚢胞性線維症	2

251. 尿素サイクル異常症

臨床試験数 : 54 / 薬物数 : 61 - (DrugBank : 15) / 標的遺伝子数 : 3 - 標的パスウェイ数 : 28

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2008-003865-23-GB (EUCTR)	08/09/2008	25/07/2008	A Phase 2, Switch-Over, Dose-Escalation Study of the Safety and Tolerability of HPN-100 (glyceryl tr ...	A Phase 2, Switch-Over, Dose-Escalation Study of the Safety and Tolerability of HPN-100 (glyceryl tr ...	Urea Cycle Disorder (urea cycle enzyme or transporter deficiency) MedDRA version: 9.1;Level: LLT;Cla ...	Product Name: glyceryl tri-(4-phenylbutyrate)(GT4P) Product Code: HPN-100 INN or Proposed INN: NA Other ...	Hyperion Therapeutics Limited	NULL	Not Recruiting			Female: yes Male: yes	16	Phase 2	United Kingdom

臨床試験数 : 1,695 / 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00590538 (ClinicalTrials.gov)	February 2003	27/12/2007	Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis)	A Pilot Trial of Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygous Cystic Fibrosis Pati ...	Cystic Fibrosis	Drug: Sodium 4-Phenylbutyrate;Drug: Genistein (Unconjugated Isoflavones 100);Drug: Placebo	Children's Hospital of Philadelphia	Cystic Fibrosis Foundation Therapeutics	Terminated	18 Years	N/A	All	9	Phase 1/Phase 2	United States
2	NCT00016744 (ClinicalTrials.gov)	September 2001	31/5/2001	Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis)	A Pilot Trial of Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous Cystic Fibrosis Patien ...	Cystic Fibrosis	Drug: Sodium 4-Phenylbutyrate(4PBA);Drug: Unconjugated Isoflavones 100 (PTI G-4660, 87% Genistein);D ...	Children's Hospital of Philadelphia	Cystic Fibrosis Foundation Therapeutics;National Center for Research Resources (NCRR)	Completed	18 Years	N/A	Both	12	Phase 1/Phase 2	United States