SULFAMETHOXAZOLE ( DrugBank: Sulfamethoxazole )

5 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
44	多発血管炎性肉芽腫症	1
49	全身性エリテマトーデス	1
61	自己免疫性溶血性貧血	1
85	特発性間質性肺炎	2
299	嚢胞性線維症	7

44. 多発血管炎性肉芽腫症

臨床試験数 : 98 / 薬物数 : 108 - (DrugBank : 28) / 標的遺伝子数 : 22 - 標的パスウェイ数 : 81

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03919435 (ClinicalTrials.gov)	March 27, 2019	5/4/2019	TEMPO Study: Trimethoprim-Sulfamethoxazole in Granulomatosis With Polyangiitis	Trimethoprim-Sulfamethoxazole Effects on the Nasal Microbiome in Granulomatosis With Polyangiitis	Granulomatosis With Polyangiitis;Wegener Granulomatosis	Drug: Trimethoprim Sulfamethoxazole	University of Pennsylvania	NULL	Active, not recruiting	18 Years	N/A	All	30	Phase 1/Phase 2	United States

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49. 全身性エリテマトーデス

臨床試験数 : 993 / 薬物数 : 702 - (DrugBank : 184) / 標的遺伝子数 : 116 - 標的パスウェイ数 : 200

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03042260 (ClinicalTrials.gov)	March 1, 2017	10/1/2017	Prophylactic Trimethoprim/Sulfamethoxazoleto Prevent Severe Infections in Patients With Lupus Erythe ...	Prophylactic Trimethoprim-Sulfamethoxazolefor the Prevention of Serious Infections in Patients With ...	Lupus Erythematosus, Systemic	Drug: Trimethoprim-Sulfamethoxazole;Drug: Placebo Oral Tablet	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	National Council of Science and Technology, Mexico	Recruiting	18 Years	N/A	All	310	Phase 4	Mexico

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61. 自己免疫性溶血性貧血

臨床試験数 : 146 / 薬物数 : 131 - (DrugBank : 59) / 標的遺伝子数 : 28 - 標的パスウェイ数 : 158

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-002844-66-IT (EUCTR)	23/11/2021	23/09/2021	Study of the Efficacy and Safety of Parsaclisib in Participants with Primary Warm Autoimmune Hemolyt ...	A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsacli ...	Primary Warm Autoimmune Hemolytic Anemia MedDRA version: 20.0;Level: LLT;Classification code 1000382 ...	Product Name: Parsaclisib (1 mg) Product Code: [INCB050465] Other descriptive name: INCB050465 HYDROCH ...	INCYTE CORPORATION	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 3	United States;Spain;Ukraine;Austria;Israel;United Kingdom;Italy;France;Canada;Belgium;Poland;Germany ...

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85. 特発性間質性肺炎

臨床試験数 : 627 / 薬物数 : 443 - (DrugBank : 120) / 標的遺伝子数 : 99 - 標的パスウェイ数 : 212

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01777737 (ClinicalTrials.gov)	November 25, 2013	25/1/2013	Study to Test the Validity of the Treatment of Idiopathic Pulmonary Fibrosis With Cotrimoxazole	Pilot Study Phase III to Evaluate the Efficacy and Safety of Trimethoprim-sulfamethoxazolein the Tre ...	Idiopathic Pulmonary Fibrosis	Drug: Cotrimoxazole;Drug: Placebo	Fundación Pública Andaluza para la gestión de la Investigación en Sevilla	Junta de Andalucia	Terminated	18 Years	80 Years	All	3	Phase 3	Spain
2	EUCTR2012-005409-38-ES (EUCTR)	19/04/2013	29/01/2013	First study to test the validity of the treatment of the disease called idiopathic pulmonary fibrosi ...	Pilot study phase III to evaluate the efficacy and safety of Trimethoprim-sulfamethoxazolein the tre ...	Ambulatory patients, men and women, with well-established diagnosis of idiopathic pulmonary fibrosis ...	Trade Name: SEPTRIN INN or Proposed INN: TRIMETHOPRIM Other descriptive name: TRIMETHOPRIM INN or Propo ...	Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla (FISEVI)	NULL	Not Recruiting			Female: yes Male: yes	56	Phase 3	Spain

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299. 嚢胞性線維症

臨床試験数 : 1,695 / 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-003501-10-NO (EUCTR)	08/03/2021	29/05/2020	Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with ...	Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with ...	Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]	Trade Name: Amoxicillin Product Name: Amoxicillin INN or Proposed INN: AMOXICILLIN Trade Name: Amoxicil ...	Vãstre Gõtalandsregionen, Sweden	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 4	Denmark;Norway;Sweden
2	EUCTR2019-003501-10-DK (EUCTR)	22/01/2021	22/04/2020	Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with ...	Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with ...	Cystic fibrosis MedDRA version: 22.1;Level: LLT;Classification code 10068288;Term: Cystic fibrosis p ...	INN or Proposed INN: AMOXICILLIN INN or Proposed INN: CLAVULANIC ACID INN or Proposed INN: AMOXICILLIN ...	Västra Götalandsregionen	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 4	Denmark;Norway;Sweden
3	EUCTR2019-003501-10-SE (EUCTR)	08/04/2020	07/04/2020	Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with ...	Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with ...	Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]	INN or Proposed INN: AMOXICILLIN INN or Proposed INN: CLAVULANIC ACID INN or Proposed INN: AMOXICILLIN ...	Västra Götalandsregionen	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 4	Denmark;Norway;Sweden
4	NCT03489629 (ClinicalTrials.gov)	April 3, 2018	29/3/2018	STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)	STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)	Cystic Fibrosis	Drug: Trimethoprim Sulfamethoxazole(TMP/SMX);Drug: Minocycline;Drug: Mupirocin;Drug: Chlorhexidine G ...	University of North Carolina, Chapel Hill	University of Washington;Cook Children's Medical Center;Indiana University;University of Michigan;Un ...	Recruiting	2 Years	45 Years	All	42	Phase 2	United States
5	EUCTR2013-000219-25-IT (EUCTR)	18/07/2013	12/04/2018	MRSA study.	Early eradication of S. Aureus (MRSA) in patients with cystic fibrosis: a randomized multicenter stu ...	Patients affected by cystic fibrosis and who present an initial infection of MRSA.;Therapeutic area: ...	Product Name: Rifampin INN or Proposed INN: RIFAMPICIN Product Name: Trimethoprim-sulfamethoxazole INN ...	AOU Meyer	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 3	Italy
6	NCT01594827 (ClinicalTrials.gov)	October 2012	7/5/2012	Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)	Persistent MRSA Eradication Protocol (PMEP)	Cystic Fibrosis	Drug: Inhaled Vancomycin;Drug: Placebo (Sterile Water);Drug: Rifampin;Drug: Trimethoprim/Sulfamethox ...	Johns Hopkins University	Case Western Reserve University;Cystic Fibrosis Foundation	Completed	12 Years	N/A	All	29	Phase 2	United States
7	NCT01349192 (ClinicalTrials.gov)	April 2011	4/5/2011	Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)	Early MRSA Therapy in CF - Culture Based vs. Observant Therapy (Treat or Observe) (Star-TOO - STaph ...	Cystic Fibrosis;Methicillin-resistant Staphylococcus Aureus	Drug: Rifampin;Drug: Trimethoprim/Sulfamethoxazole;Drug: Minocycline;Drug: Mupirocin;Drug: chlorhexi ...	University of North Carolina, Chapel Hill	CF Therapeutics Development Network Coordinating Center;Seattle Children's Hospital;Washington Unive ...	Terminated	4 Years	45 Years	All	47	Phase 2	United States

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