KETAMINE ( DrugBank: Ketamine )

6 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
6	パーキンソン病	3
13	多発性硬化症／視神経脊髄炎	2
70	広範脊柱管狭窄症	4
113	筋ジストロフィー	1
156	レット症候群	1
215	ファロー四徴症	1

6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-000041-40-NL (EUCTR)	22/02/2022	10/11/2021	A study to investigate the effects of repeated low doses of psilocybin and ketamineon cognitive and ...	A study to investigate the effects of repeated low doses of psilocybin and ketamineon cognitive and ...	Parkinson's disease;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Product Name: Psilocybin INN or Proposed INN: Psilocybine Product Name: Ketamine INN or Proposed INN: K ...	Maastricht University	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	34	Phase 2	Netherlands
2	NCT04944017 (ClinicalTrials.gov)	November 23, 2021	22/6/2021	Ketamine for the Treatment of Depression in Parkinson's Disease	Ketamine for the Treatment of Depression in Parkinson's Disease (KET-PD)	Parkinson's Disease;Depression	Drug: Ketamine Infusion;Other: Placebo - Saline Infusion	Yale University	Fox (Michael J.) Foundation for Parkinson's Research	Recruiting	40 Years	80 Years	All	56	Phase 2	United States
3	NCT04912115 (ClinicalTrials.gov)	October 5, 2021	25/5/2021	Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamineto Treat Levodopa-Induced Dyski ...	A Multi-Center, Phase II, Randomized, Double-Blind, Prospective, Active Placebo- Controlled Trial of ...	Dyskinesias;Movement Disorders;Central Nervous System Diseases;Nervous System Diseases;Neurologic Ma ...	Drug: Ketamine;Drug: Midazolam	PharmaTher Inc.	NULL	Suspended	30 Years	85 Years	All	30	Phase 2	United States

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13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05378100 (ClinicalTrials.gov)	January 1, 2023	12/5/2022	Ketamine for Multiple Sclerosis Fatigue	Low-Dose Ketamine Infusion for the Treatment of Multiple Sclerosis Fatigue (INKLING-MS)	Multiple Sclerosis Fatigue	Drug: Ketamine;Drug: Midazolam	Johns Hopkins University	United States Department of Defense	Recruiting	18 Years	65 Years	All	110	Phase 2	United States
2	NCT03500289 (ClinicalTrials.gov)	August 10, 2018	4/4/2018	Ketamine for Treatment of MS Fatigue	Ketamine for Treatment of Multiple Sclerosis-related Fatigue	Multiple Sclerosis;Fatigue	Drug: Ketamine;Drug: Midazolam	Johns Hopkins University	National Multiple Sclerosis Society	Completed	18 Years	65 Years	All	18	Phase 1/Phase 2	United States

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70. 広範脊柱管狭窄症

臨床試験数 : 95 / 薬物数 : 169 - (DrugBank : 61) / 標的遺伝子数 : 68 - 標的パスウェイ数 : 90

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03088306 (ClinicalTrials.gov)	July 1, 2017	22/2/2017	Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients	Comparative Effectiveness of Multi-modal Pain Management Versus Standard Intra- and Post-operative A ...	Lumbar Spinal Stenosis;Lumbar Spinal Instability;Lumbar Spine Degeneration	Drug: Standard analgesia use [Oxygen];Drug: Standard analgesia use [Hydromorphone];Drug: Standard an ...	Johns Hopkins University	North American Spine Society	Completed	18 Years	100 Years	All	49	Early Phase 1	United States
2	EUCTR2016-002887-14-FI (EUCTR)	31/10/2016	14/10/2016	Dose-response of ketamine in patient controlled analgesia in orthopaedic surgery patients	Dose response study of Patient Controlled Analgesia (PCA) of S-ketaminein orthopaedic spine surgery ...	Patients who are scheduled for elective posterolateral lumbar spine fusion with bilateral transpedic ...	Trade Name: Ketanest-S INN or Proposed INN: KETAMINE Trade Name: Oxycodone Orion INN or Proposed INN: O ...	University of Turku	NULL	Not Recruiting			Female: yes Male: yes	100	Phase 1;Phase 4	Finland
3	EUCTR2012-000747-26-FI (EUCTR)	27/04/2012	02/04/2012	Ketamine to reduce postoperative pain in back surgery	Administration of S-Ketamine during spinal surgery to reduce postoperative pain	adult patients undergoing spinal surgery MedDRA version: 14.1;Level: LLT;Classification code 1004159 ...	Trade Name: Ketanest-S Product Name: Ketanest-S Other descriptive name: ESKETAMINE HYDROCHLORIDE	Helsinki Universiy Central Hospital	NULL	Not Recruiting			Female: yes Male: yes	192	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Finland
4	NCT01275547 (ClinicalTrials.gov)	January 2011	11/1/2011	The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam	The Analgesic Effect of Combined Treatment With Intranasal S-Ketamineand Intranasal Midazolam Compar ...	Analgesia, Patient-controlled;Spinal Stenosis	Drug: s-ketamine & midazolam;Drug: Morphine PCA	University Hospital, Basel, Switzerland	NULL	Completed	18 Years	N/A	Both	22	Phase 2/Phase 3	Switzerland

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113. 筋ジストロフィー

臨床試験数 : 646 / 薬物数 : 471 - (DrugBank : 105) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 170

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01645098 (ClinicalTrials.gov)	August 2011	8/6/2012	Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy	Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy	Duchenne Muscular Dystrophy	Drug: Ketamine;Drug: Dexmedetomidine	Nationwide Children's Hospital	NULL	Completed	N/A	N/A	Male	53	N/A	United States

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156. レット症候群

臨床試験数 : 44 / 薬物数 : 61 - (DrugBank : 23) / 標的遺伝子数 : 57 - 標的パスウェイ数 : 83

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03633058 (ClinicalTrials.gov)	March 12, 2019	8/8/2018	A Study to Evaluate Ketamine for the Treatment of Rett Syndrome	A Randomized, Double-blind, Placebo-controlled, Cross-over Study to Assess the Safety, Tolerability ...	Rett Syndrome	Drug: Ketamine	Rett Syndrome Research Trust	Vanderbilt University Medical Center	Completed	6 Years	12 Years	Female	24	Phase 2	United States

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215. ファロー四徴症

臨床試験数 : 18 / 薬物数 : 26 - (DrugBank : 14) / 標的遺伝子数 : 13 - 標的パスウェイ数 : 45

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR-IOR-16008571	2016-06-06	2016-05-31	Premedication for children with Tetralogy of Fallot	A comparative evalution of varies premedication regimes on children with Tetralogy of Fallot	Tetralogy of Fallot	oral dexmedetomidine:oral dexmedetomidine;oral ketamine:oral ketamine;oral dexmedetomidine mixed wit ...	Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University	NULL	Recruiting			Both	oral dexmedetomidine:20;oral ketamine:20;oral dexmedetomidine mixed with ketamine:20;		China

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