Venglustat GZ/SAR402671 ( DrugBank: Venglustat )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
6	パーキンソン病	1
67	多発性嚢胞腎	1

6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02906020 (ClinicalTrials.gov)	December 15, 2016	14/9/2016	A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation	Multicenter, Randomized, Double-blind, Placebo Controlled Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of GZ/SAR402671 in Patients With Early-stage Parkinson's Disease Carrying a GBA Mutation or Other Pre-specified Variant.	Parkinson's Disease	Drug: venglustat GZ/SAR402671;Drug: Placebo	Genzyme, a Sanofi Company	NULL	Terminated	18 Years	80 Years	All	270	Phase 2	United States;Austria;Canada;France;Germany;Greece;Israel;Italy;Japan;Norway;Portugal;Singapore;Spain;Sweden;Taiwan;United Kingdom

67. 多発性嚢胞腎

臨床試験数 : 221 / 薬物数 : 212 - (DrugBank : 55) / 標的遺伝子数 : 40 - 標的パスウェイ数 : 151

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03687554 (ClinicalTrials.gov)	October 5, 2018	26/9/2018	Effect of Venglustat in Patients With Renal Impairment	A Phase I, Single-Center, Open-label, Single Dose Pharmacokinetic and Tolerability Study of GZ402671 in Subjects With Mild, Moderate and Severe Renal Impairment, and in Matched Subjects With Normal Renal Function	Healthy Volunteers;Polycystic Kidney, Autosomal Dominant	Drug: Venglustat GZ/SAR402671	Genzyme, a Sanofi Company	NULL	Completed	18 Years	79 Years	All	24	Phase 1	United States