Imipenem ( DrugBank: Imipenem )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
60再生不良性貧血1
299嚢胞性線維症1

60. 再生不良性貧血


臨床試験数 : 245 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2014-001546-25-NL
(EUCTR)
06/01/201519/11/2014Short versus extended antibiotic treatment for fever during low white blood cell counts in hematology patients with fever of unknown origin.Short versus extended antibiotic treatment with a carbapenem for high-risk febrile neutropenia in hematology patients with Fever of Unknown Origin: a randomized multicenter open-label non-inferiority trial. - SHORT-trial Febrile neutropenia
MedDRA version: 19.1;Level: PT;Classification code 10063581;Term: Stem cell transplant;System Organ Class: 10042613 - Surgical and medical procedures
MedDRA version: 19.1;Level: LLT;Classification code 10002969;Term: Aplastic anemia;System Organ Class: 10005329 - Blood and lymphatic system disorders
MedDRA version: 19.1;Classification code 10003999;Term: Bacteremia;System Organ Class: 10021881 - Infections and infestations
MedDRA version: 19.1;Classification code 10007810;Term: Catheter related infection;Classification code 10028566;Term: Myeloma;System Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
MedDRA version: 19.1;Classification code 10062957;Term: Catheter bacteraemia;Classification code 10025310;Term: Lymphoma;Classification code 10024329;Term: Leukemia;Classification code 10056520;Term: Catheter site infection;Classification code 10016288;Term: Febrile neutropenia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Bacterial Infections and Mycoses [C01]
Trade Name: imipenem-cilastatine
Product Name: imipenem / cilastatine
Product Code: RVG 101614
INN or Proposed INN: IMIPENEM
INN or Proposed INN: Cilastatin
Other descriptive name: CILASTATIN
Trade Name: Meropenem
Product Name: meropenem
Product Code: RVG 105155
INN or Proposed INN: Meropenem
Other descriptive name: MEROPENEM
VU University Medical CenterNULLNot RecruitingFemale: yes
Male: yes
240Phase 4Netherlands

299. 嚢胞性線維症


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05561764
(ClinicalTrials.gov)
January 3, 202327/9/2022Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic FibrosisA Multicenter, Open-label Study to Determine the Pharmacokinetics, Safety, and Outcomes of Imipenem/Cilastatin/Relebactam During Treatment of Acute Pulmonary Exacerbations in Adolescent and Adult Patients With Cystic FibrosisCystic Fibrosis;Pneumonia, BacterialDrug: Imipenem/Cilastatin/RelebactamHartford HospitalMerck Sharp & Dohme LLC;Q2 Solutions;Connecticut Children's Medical Center;St. Christopher's Hospital for Children;University of Texas Southwestern Medical Center;University of Pittsburgh Medical Center;Indiana University Health Methodist Hospital;James Whitcomb Riley Hospital for ChildrenRecruiting12 YearsN/AAll16Phase 4United States