KETAMINE ( DrugBank: Ketamine )


1 disease
告示番号疾患名(ページ内リンク)臨床試験数
70広範脊柱管狭窄症4

70. 広範脊柱管狭窄症


臨床試験数 : 95 薬物数 : 169 - (DrugBank : 61) / 標的遺伝子数 : 68 - 標的パスウェイ数 : 90
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PhaseCountries
1NCT03088306
(ClinicalTrials.gov)
July 1, 201722/2/2017Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery PatientsComparative Effectiveness of Multi-modal Pain Management Versus Standard Intra- and Post-operative Analgesia: Randomized Controlled Clinical Trial to Reduce Post-operative Pain and Opioid Use Among Patients Undergoing Lumbar Spine SurgeryLumbar Spinal Stenosis;Lumbar Spinal Instability;Lumbar Spine DegenerationDrug: Standard analgesia use [Oxygen];Drug: Standard analgesia use [Hydromorphone];Drug: Standard analgesia use [Volatile Anesthesia];Drug: Standard analgesia use [Fentanyl];Drug: Multi-modal pain management [Acetaminophen + Gabapentin];Drug: Multi-modal pain management [Fentanyl];Drug: Multi-modal pain management [Intravenous Ketamine];Drug: Multi-modal pain management [Valium + Gabapentin]Johns Hopkins UniversityNorth American Spine SocietyCompleted18 Years100 YearsAll49Early Phase 1United States
2EUCTR2016-002887-14-FI
(EUCTR)
31/10/201614/10/2016Dose-response of ketamine in patient controlled analgesia in orthopaedic surgery patientsDose response study of Patient Controlled Analgesia (PCA) of S-ketamine in orthopaedic spine surgery patients - DoseRespKeta Patients who are scheduled for elective posterolateral lumbar spine fusion with bilateral transpedicular screw instrumentation
MedDRA version: 19.0;Level: LLT;Classification code 10041595;Term: Spinal stenosis lumbar;System Organ Class: 100000004859;Therapeutic area: Body processes [G] - Bones and nerves physological processes [G11]
Trade Name: Ketanest-S
INN or Proposed INN: KETAMINE
Trade Name: Oxycodone Orion
INN or Proposed INN: OXYCODONE
University of TurkuNULLNot RecruitingFemale: yes
Male: yes
100Phase 1;Phase 4Finland
3EUCTR2012-000747-26-FI
(EUCTR)
27/04/201202/04/2012Ketamine to reduce postoperative pain in back surgeryAdministration of S-Ketamine during spinal surgery to reduce postoperative pain adult patients undergoing spinal surgery
MedDRA version: 14.1;Level: LLT;Classification code 10041595;Term: Spinal stenosis lumbar;System Organ Class: 10028395 - Musculoskeletal and connective tissue disorders ;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
Trade Name: Ketanest-S
Product Name: Ketanest-S
Other descriptive name: ESKETAMINE HYDROCHLORIDE
Helsinki Universiy Central HospitalNULLNot Recruiting Female: yes
Male: yes
192 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): yesFinland
4NCT01275547
(ClinicalTrials.gov)
January 201111/1/2011The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal MidazolamThe Analgesic Effect of Combined Treatment With Intranasal S-Ketamine and Intranasal Midazolam Compared With Morphine Patient Controlled Analgesia in Spinal Surgery PatientsAnalgesia, Patient-controlled;Spinal StenosisDrug: s-ketamine & midazolam;Drug: Morphine PCAUniversity Hospital, Basel, SwitzerlandNULLCompleted18 YearsN/ABoth22Phase 2/Phase 3Switzerland