Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's Disease
A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT 130) in Early Manifest Huntington's Disease A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Dose ...
Safety and Efficacy of AMT-130 in European Adults with Early Manifest Huntington Disease
A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT 130) in Early Manifest Huntington Disease - Safety and Efficacy of AMT-130 in European Adults with Early Manifest Huntington Disease A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Dose ...
Huntington Disease MedDRA version: 20.0;Level: PT;Classification code 10070668;Term: Huntington's disease;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Huntington Disease MedDRA version: 20.0;Level: PT;Classification code 10070668;Term: Huntington's di ...
Safety and Efficacy of AMT-130 in European Adults with Early Manifest Huntington Disease
A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT 130) in Early Manifest Huntington Disease - Safety and Efficacy of AMT-130 in European Adults with Early Manifest Huntington Disease A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Dose ...
Huntington Disease MedDRA version: 20.0;Level: PT;Classification code 10070668;Term: Huntington's disease;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Huntington Disease MedDRA version: 20.0;Level: PT;Classification code 10070668;Term: Huntington's di ...
Product Name: rAAV5-miHTT Product Code: AMT-130 Other descriptive name: ADENO-ASSOCIATED VIRUS SEROTYPE 5 ENCODING A MICRORNA TARGETED TO HUMAN HUNTINGTIN GENE Product Name: rAAV5-miHTT Product Code: AMT-130 Other descriptive name: ADENO-ASSOCIATED VIRUS SEROTYPE 5 ENCODING A MICRORNA TARGETED TO HUMAN HUNTINGTIN GENE Product Name: rAAV5-miHTT Product Code: AMT-130 Other descriptive name: ADENO-ASSOCIATED VIRUS SEROTYP ...
Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Dise ...
A Phase I/II, Randomized, Double-Blind, Sham Control Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT-130) in Early Manifest Huntington's Disease A Phase I/II, Randomized, Double-Blind, Sham Control Study to Explore Safety, Tolerability, and Effi ...
Huntington's Disease
Genetic: intra-striatal rAAV5-miHTT;Other: Imitation (sham) surgery