Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D00306	Dronabinol	8件: 2, 8, 13, 36, 46, 96, 271, 298
3	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D10915	Cannabidiol	20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
4	CNR2	1件: Neuroactive ligand-receptor interaction	D00306	Dronabinol	7件: 8, 13, 36, 46, 96, 271, 298
5	CNR2	1件: Neuroactive ligand-receptor interaction	D10915	Cannabidiol	18件: 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
6	MAPK14	62件: Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D10959	Neflamapimod	1件: 8
7	ADRA1D	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D00454	Olanzapine	2件: 2, 8
8	ADRA1B	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D00454	Olanzapine	2件: 2, 8
9	ADRA1A	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D00454	Olanzapine	2件: 2, 8
10	ADRA2A	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D08482	Rilmenidine	1件: 8

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