Metformin hydrochloride ( DrugBank: Metformin )


5 diseases
告示番号疾患名(ページ内リンク)臨床試験数
81先天性副腎皮質酵素欠損症1
158結節性硬化症1
265脂肪萎縮症1
299嚢胞性線維症1
301黄斑ジストロフィー1

81. 先天性副腎皮質酵素欠損症


臨床試験数 : 87 薬物数 : 87 - (DrugBank : 23) / 標的遺伝子数 : 12 - 標的パスウェイ数 : 68
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2013-002395-40-BE
(EUCTR)
24/03/201419/11/2013Prospective intervention trial with adjuvant metformin in girls and boys with classic congenital adrenal hyperplasia.Prospective intervention trial with adjuvant metformin in girls and boys with classic CAH (METFOR CAH). - METFOR CAH congenital adrenal hyperplasia (CAH)
MedDRA version: 16.1;Level: LLT;Classification code 10010323;Term: Congenital adrenal hyperplasia;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Trade Name: Metformine Sandoz 850 mg filmomhulde tabletten
Product Name: Metformine
INN or Proposed INN: METFORMIN HYDROCHLORIDE
Other descriptive name: METFORMIN HYDROCHLORIDE
Ghent University HospitalNULLNot RecruitingFemale: yes
Male: yes
90Phase 3Belgium

158. 結節性硬化症


臨床試験数 : 112 薬物数 : 71 - (DrugBank : 19) / 標的遺伝子数 : 35 - 標的パスウェイ数 : 118
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2011-001319-30-GB
(EUCTR)
04/04/201205/09/2011Metformin as a treatment for people with the genetic disease Tuberous Sclerosis Complex.A randomized, double-blind, parallel group, placebo-controlled trial of metformin in tuberous sclerosis complex. - Metformin in Tuberous Sclerosis Complex (MiTS) V1.0 Tuberous Sclerosis Complex
MedDRA version: 14.1;Level: PT;Classification code 10045138;Term: Tuberous sclerosis;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Trade Name: metformin (generic)
Product Name: Metformin
Product Code: n/a
INN or Proposed INN: metformin hydrochloride
Other descriptive name: -
University Hospitals Bristol NHS Foundation TrustNULLNot RecruitingFemale: yes
Male: yes
100Phase 4United Kingdom

265. 脂肪萎縮症


臨床試験数 : 112 薬物数 : 155 - (DrugBank : 55) / 標的遺伝子数 : 25 - 標的パスウェイ数 : 97
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00015691
(ClinicalTrials.gov)
April 20011/5/2001Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat AbnormalitiesA Randomized, Double-Blind, Placebo-Controlled Study of Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Subjects With Hyperinsulinemia and Elevated Waist/Hip RatioHIV Infections;Lipodystrophy;HyperinsulinemiaDrug: Metformin hydrochloride;Drug: Rosiglitazone maleateNational Institute of Allergy and Infectious Diseases (NIAID)NULLCompleted18 Years65 YearsBoth105N/AUnited States

299. 嚢胞性線維症


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04530383
(ClinicalTrials.gov)
February 14, 202224/8/2020Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related DiabetesA Randomized, Double-blind, Crossover Clinical Trial of Metformin in Those With CFRD on CFTR Modulator Therapy to Improve Ion Channel FunctionCystic Fibrosis-related Diabetes;Cystic FibrosisDrug: Metformin HydrochlorideUniversity of Kansas Medical CenterNULLRecruiting18 YearsN/AAll36Phase 2United States

301. 黄斑ジストロフィー


臨床試験数 : 46 薬物数 : 42 - (DrugBank : 11) / 標的遺伝子数 : 9 - 標的パスウェイ数 : 67
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04545736
(ClinicalTrials.gov)
November 23, 202010/9/2020Oral Metformin for Treatment of ABCA4 RetinopathyOral Metformin for Treatment of ABCA4 RetinopathyABCA4 Retinopathy;Stargardt Disease;Retinal Dystrophy;Retinal DegenerationDrug: Metformin hydrochlorideNational Eye Institute (NEI)NULLRecruiting12 YearsN/AAll38Phase 1/Phase 2United States