PYRIDOXINE ( DrugBank: Pyridoxine )


3 diseases
告示番号疾患名(ページ内リンク)臨床試験数
93原発性胆汁性胆管炎1
145ウエスト症候群1
320先天性グリコシルホスファチジルイノシトール(GPI)欠損症1

93. 原発性胆汁性胆管炎


臨床試験数 : 298 薬物数 : 252 - (DrugBank : 59) / 標的遺伝子数 : 35 - 標的パスウェイ数 : 115
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2006-006742-34-GB
(EUCTR)
20/12/200703/06/2007The effect of Ezetimibe or pyridoxine in Patients with Primary Biliary Cirrhosis.The effect of Ezetimibe or pyridoxine in Patients with Primary Biliary Cirrhosis. primary biliary cirrhosis
MedDRA version: 9.1;Level: LLT;Classification code 10036680;Term: Primary biliary cirrhosis
Trade Name: Ezetrol
Product Name: Ezetimibe
Product Code: EZT
INN or Proposed INN: EZETIMIBE
Trade Name: pyridoxine 10mg BP
Product Name: pyridoxine 10mg
Product Code: A11HA02
INN or Proposed INN: PYRIDOXINE
Barts and The London NHS TrustNULLNot Recruiting Female: yes
Male: yes
70 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): yesUnited Kingdom

145. ウエスト症候群


臨床試験数 : 43 薬物数 : 52 - (DrugBank : 15) / 標的遺伝子数 : 28 - 標的パスウェイ数 : 26
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01828437
(ClinicalTrials.gov)
November 20127/4/2013Addition of Pyridoxine to Prednisolone in Infantile SpasmsAddition of Pyridoxine to Prednisolone in the Treatment of Infantile Spasms: A Randomized Controlled TrialInfantile SpasmsDrug: Pyridoxine plus prednisolone;Drug: PrednisoloneLady Hardinge Medical CollegeNULLCompleted3 Months36 MonthsAll62Phase 3India

320. 先天性グリコシルホスファチジルイノシトール(GPI)欠損症


臨床試験数 : 3 薬物数 : 2 - (DrugBank : 2) / 標的遺伝子数 : 0 - 標的パスウェイ数 : 0
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1JPRN-UMIN000024185
2014/07/3127/09/2016Prospective non- control non- randomized, open-label study about efficacy of vitamin B6 for inherited GPI deficiencyProspective non- control non- randomized, open-label study about efficacy of vitamin B6 for inherited GPI deficiency - Interventional study of vitamin B6 for inherited GPI deficiency Inherited GPI deficiencyInitial dose: pyridoxine 10-15 mg/kg/day
1-2 weeks after the initiation, the dose is increased to maintenance dose, if there is no adverse effect.
Maintenance dose: pyridoxine 20-30 mg/kg/day
We prescribe pyridoxine for a year.
The Graduate School of Medicine, Osaka UniversityDepartment of Child Neurology, Tottori University HospitalComplete: follow-up completeNot applicableNot applicableMale and Female15Not selectedJapan