Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D07945 Fenfluramine 4件: 140, 144, 145, 149
2 CNR1 4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling D10915 Cannabidiol 20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
3 CNR2 1件: Neuroactive ligand-receptor interaction D10915 Cannabidiol 8件: 145, 156, 157, 158, 193, 206, 226, 271
4 ABAT 7件: Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, Metabolic pathways, GABAergic synapse D00535 Vigabatrin 2件: 145, 158
5 GABRA1 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
6 GABRA2 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
7 GABRA3 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
8 GABRA4 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
9 GABRA5 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
10 GABRA6 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
11 GABRB1 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
12 GABRB2 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
13 GABRB3 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
14 GABRD 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
15 GABRE 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
16 GABRG1 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
17 GABRG2 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
18 GABRG3 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
19 GABRP 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
20 NR3C1 1件: Neuroactive ligand-receptor interaction D00407 Methylprednisolone 12件: 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
21 NR3C1 1件: Neuroactive ligand-receptor interaction D00472 Prednisolone 8件: 145, 162, 222, 269, 271, 296, 299, 300
22 HTR1D 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction D07945 Fenfluramine 4件: 140, 144, 145, 149
23 HTR2A 5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels D07945 Fenfluramine 4件: 140, 144, 145, 149
24 HTR2C 5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels D07945 Fenfluramine 4件: 140, 144, 145, 149
25 MC2R 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome D00146 Corticotropin 12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222
26 MC2R 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome D00284 Tetracosactide 5件: 78, 83, 113, 145, 222
27 MTNR1A 2件: Neuroactive ligand-receptor interaction, Circadian entrainment D08170 Melatonin 12件: 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202
28 MTNR1B 2件: Neuroactive ligand-receptor interaction, Circadian entrainment D08170 Melatonin 12件: 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202
29 GABRQ 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D04300 Ganaxolone 4件: 145, 152, 158, 206
30 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07945 Fenfluramine 4件: 140, 144, 145, 149