CEFTRIAXONE ( DrugBank: Ceftriaxone )


4 diseases
IDDisease name (Link within this page)Number of trials
2Amyotrophic lateral sclerosis2
6Parkinson disease1
46Malignant rheumatoid arthritis1
97Ulcerative colitis1

2. Amyotrophic lateral sclerosis


Clinical trials : 645 Drugs : 589 - (DrugBank : 163) / Drug target genes : 150 - Drug target pathways : 225
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2007-004165-17-IT
(EUCTR)
25/09/200715/10/2007Efficacy assessment of ceftriaxone therapy in patients with amyotrophic lateral sclerosis. - NDEfficacy assessment of ceftriaxone therapy in patients with amyotrophic lateral sclerosis. - ND Amyotrophic lateral sclerosis (ALS)
MedDRA version: 6.1;Level: PT;Classification code 10002026
INN or Proposed INN: CeftriaxoneAZIENDA OSPEDALIERA PISANANULLNot RecruitingFemale: yes
Male: yes
Italy
2NCT00349622
(ClinicalTrials.gov)
July 20065/7/2006Clinical Trial Ceftriaxone in Subjects With ALSClinical Trial Ceftriaxone in Subjects With Amyotrophic Lateral Sclerosis (ALS)Amyotrophic Lateral Sclerosis;ALSDrug: ceftriaxone;Other: placeboMassachusetts General HospitalNational Institute of Neurological Disorders and Stroke (NINDS)Completed18 YearsN/AAll513Phase 3United States;Canada;Puerto Rico

6. Parkinson disease


Clinical trials : 2,307 Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03413384
(ClinicalTrials.gov)
February 15, 20198/1/2018To Assess the Efficacy and Safety of Ceftriaxone in Patients With Mild to Moderate Parkinson's Disease DementiaA Randomized, Double Blinded, Placebo-controlled Phase II Study to Assess the Efficacy and Safety of Ceftriaxone in Patients With Mild to Moderate Parkinson's Disease DementiaParkinson's Disease DementiaDrug: Ceftriaxone;Other: PlaceboBrainX CorporationVirginia Contract Research Organization Co., Ltd.Recruiting50 Years80 YearsAll106Phase 2Taiwan

46. Malignant rheumatoid arthritis


Clinical trials : 4,356 Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2015-003333-95-LT
(EUCTR)
21/07/201609/05/2016A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects with Rheumatoid Arthritis who are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate (SELECT-COMPARE)A Phase 3, Randomized, Double-Blind Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects with Moderately to Severely Active Rheumatoid Arthritis Who are on a Stable Background of Methotrexate (MTX) and Who Have an Inadequate Response to MTX (MTX-IR) Stroke (ischaemic stroke or intracerebral hemorrhage)
MedDRA version: 22.1;Level: PT;Classification code 10061256;Term: Ischaemic stroke;System Organ Class: 10029205 - Nervous system disorders
MedDRA version: 21.1;Level: LLT;Classification code 10022754;Term: Intracerebral hemorrhage;System Organ Class: 10029205 - Nervous system disorders
MedDRA version: 22.1;Classification code 10042244;Term: Stroke;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
Trade Name: Paracetamol
Product Name: Paracetamol
INN or Proposed INN: Paracetamol
Other descriptive name: PARACETAMOL
Trade Name: Ceftriaxone
Product Name: Ceftriaxone
INN or Proposed INN: CEFTRIAXONE
Trade Name: Metoclopramide
Product Name: Metoclopramide
INN or Proposed INN: METOCLOPRAMIDE
AbbVie Deutschland GmbH & Co. KGNULLNot RecruitingFemale: yes
Male: yes
1500Phase 3Greece;Netherlands;Hungary;Norway;Poland;Italy;United Kingdom;Germany;Estonia

97. Ulcerative colitis


Clinical trials : 2,630 Drugs : 1,459 - (DrugBank : 265) / Drug target genes : 144 - Drug target pathways : 202
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03794765
(ClinicalTrials.gov)
April 1, 20194/1/2019Antibiotics as an Adjuvant in Patients With Acute Severe Ulcerative ColitisUse of Antibiotics as an Adjuvant in Patients With Acute Severe Ulcerative Colitis: A Randomised TrialUlcerative Colitis;Inflammatory Bowel Diseases;Acute Severe ColitisDrug: Ceftriaxone;Drug: Metronidazole;Other: Placebo infusionPostgraduate Institute of Medical Education and ResearchNULLCompleted13 YearsN/AAll50Phase 2India