| 1 | 12-Lead ECG | - | - | - | - | 2件: 140 140, 144 |
| 2 | Any other approved Antiepileptic Drug | - | - | - | - | 1件: 144 144 |
| 3 | Cannabidiol | 1件: Cannabidiol Cannabidiol | 1件: D10915
D10915
| 2件: CNR1 CNR1,
CNR2 💬 | 4件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬 | 18件: 6 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 |
| 4 | Cannabidiol (CBD) | 1件: Cannabidiol Cannabidiol | 1件: D10915
D10915
| 2件: CNR1 CNR1,
CNR2 💬 | 4件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬 | 7件: 6 6, 13, 140, 144, 145, 156, 158 |
| 5 | Cannabidiol Oral Solution | 1件: Cannabidiol Cannabidiol | 1件: D10915
D10915
| 2件: CNR1 CNR1,
CNR2 💬 | 4件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬 | 4件: 140 140, 144, 145, 193 |
| 6 | Carisbamate | 1件: Carisbamate Carisbamate | 1件: D06573
D06573
| - | - | 1件: 144 144 |
| 7 | CBD | - | - | - | - | 12件: 2 2, 6, 8, 13, 36, 46, 140, 144, 145, 156, 158, 206 |
| 8 | CBD - Oral Solution, is known as Epidiolex, and is the approved name in the USA. | 1件: Cannabidiol Cannabidiol | 1件: D10915
D10915
| 2件: CNR1 CNR1,
CNR2 💬 | 4件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬 | 2件: 140 140, 144 |
| 9 | Clobazam | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 2件: 140 140, 144 |
| 10 | Clobazam High Dose | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 11 | Clobazam Low Dose | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 12 | Clobazam Medium Dose | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 13 | Clobazam PhEur | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 14 | Clobazam Tablets | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 15 | Clobazam Tablets 10mg | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 16 | Clobazam Tablets 20mg | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 17 | Clobazam Tablets 5mg | 1件: Clobazam Clobazam | 1件: D01253
D01253
| 16件: GABRA1 GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 | 7件: GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 18 | E2007 | - | - | - | - | 2件: 6 6, 144 |
| 19 | E2080 | - | - | - | - | 1件: 144 144 |
| 20 | Ezogabine | 1件: Ezogabine Ezogabine | 1件: D09569
D09569
| 5件: KCNQ1 KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 | 6件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬 | 2件: 2 2, 144 |
| 21 | EZOGABINE (US ONLY) | 1件: Ezogabine Ezogabine | 1件: D09569
D09569
| 5件: KCNQ1 KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 | 6件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬 | 1件: 144 144 |
| 22 | Ezogabine/retigabine | 1件: Ezogabine Ezogabine | 1件: D09569
D09569
| 5件: KCNQ1 KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 | 6件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬 | 1件: 144 144 |
| 23 | Fenfluramina | 1件: Fenfluramine Fenfluramine | 1件: D07945
D07945
| 4件: HTR2A HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 | 6件: Calcium signaling pathway Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | 2件: 140 140, 144 |
| 24 | Fenfluramina Cloridrato | 1件: Fenfluramine Fenfluramine | 1件: D07945
D07945
| 4件: HTR2A HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 | 6件: Calcium signaling pathway Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | 2件: 140 140, 144 |
| 25 | FENFLURAMINE | 1件: Fenfluramine Fenfluramine | 1件: D07945
D07945
| 4件: HTR2A HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 | 6件: Calcium signaling pathway Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | 4件: 140 140, 144, 145, 149 |
| 26 | Fenfluramine HCl, DL-Fenfluramine, (±)-Fenfluramine | 1件: Fenfluramine Fenfluramine | 1件: D07945
D07945
| 4件: HTR2A HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 | 6件: Calcium signaling pathway Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | 1件: 144 144 |
| 27 | FENFLURAMINE HYDROCHLORIDE | 1件: Fenfluramine Fenfluramine | 1件: D07945
D07945
| 4件: HTR2A HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 | 6件: Calcium signaling pathway Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | 2件: 140 140, 144 |
| 28 | FENFLURAMINE HYDROCHLORIDE (colorless) | 1件: Fenfluramine Fenfluramine | 1件: D07945
D07945
| 4件: HTR2A HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 | 6件: Calcium signaling pathway Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | 2件: 140 140, 144 |
| 29 | Fycompa | 1件: Perampanel Perampanel | 1件: D08964
D08964
| 4件: GRIA1 GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 | 16件: Amphetamine addiction Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬 | 2件: 2 2, 144 |
| 30 | GW582892 | - | - | - | - | 1件: 144 144 |
| 31 | GWP42003-P | - | - | - | - | 5件: 140 140, 144, 145, 156, 158 |
| 32 | GWP42003-P 20 mg/kg/day Dose | - | - | - | - | 2件: 140 140, 144 |
| 33 | Inovelon | 1件: Rufinamide Rufinamide | 1件: D05775
D05775
| 5件: SCN1A SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 | 3件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 34 | Investigators Choice of Approved AED | - | - | - | - | 1件: 144 144 |
| 35 | Investigators choice of approved AEDs | - | - | - | - | 1件: 144 144 |
| 36 | Lamictal | 1件: Lamotrigine Lamotrigine | 1件: D00354
D00354
| 5件: SCN1A SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 | 3件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 37 | Lamotrigine | 1件: Lamotrigine Lamotrigine | 1件: D00354
D00354
| 5件: SCN1A SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 | 3件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | 5件: 13 13, 34, 38, 114, 144 |
| 38 | Melatonin | 1件: Melatonin Melatonin | 1件: D08170
D08170
| 2件: MTNR1A MTNR1A,
MTNR1B 💬 | 2件: Circadian entrainment Circadian entrainment, Neuroactive ligand-receptor interaction 💬 | 12件: 6 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 |
| 39 | PEG | - | - | - | - | 12件: 6 6, 13, 41, 46, 65, 78, 96, 97, 140, 144, 240, 299 |
| 40 | Perampanel | 1件: Perampanel Perampanel | 1件: D08964
D08964
| 4件: GRIA1 GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 | 16件: Amphetamine addiction Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬 | 3件: 2 2, 6, 144 |
| 41 | Placebo | - | - | - | - | 27件: 3 3, 5, 6, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 |
| 42 | Potiga | 1件: Ezogabine Ezogabine | 1件: D09569
D09569
| 5件: KCNQ1 KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 | 6件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬 | 1件: 144 144 |
| 43 | RETIGABINE | 1件: Ezogabine Ezogabine | 1件: D09569
D09569
| 5件: KCNQ1 KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 | 6件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬 | 2件: 2 2, 144 |
| 44 | RETIGABINE/EZOGABINE | 1件: Ezogabine Ezogabine | 1件: D09569
D09569
| 5件: KCNQ1 KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 | 6件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬 | 1件: 144 144 |
| 45 | RUFINAMIDE | 1件: Rufinamide Rufinamide | 1件: D05775
D05775
| 5件: SCN1A SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 | 3件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 46 | Rufinamide (E2080) | 1件: Rufinamide Rufinamide | 1件: D05775
D05775
| 5件: SCN1A SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 | 3件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 47 | Rufinamide oral suspension | 1件: Rufinamide Rufinamide | 1件: D05775
D05775
| 5件: SCN1A SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 | 3件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | 1件: 144 144 |
| 48 | Sodio valproato | - | - | - | - | 1件: 144 144 |
| 49 | SOTICLESTAT | - | - | - | - | 2件: 140 140, 144 |
| 50 | TAK-935 | - | - | - | - | 2件: 140 140, 144 |
| 51 | Topimarate | - | - | - | - | 1件: 144 144 |
| 52 | Topimarato | - | - | - | - | 1件: 144 144 |
| 53 | TOPIRAMATE | 1件: Topiramate Topiramate | 1件: D00537
D00537
| 36件: CA2 CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 | 53件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 6件: 6 6, 97, 140, 144, 156, 193 |
| 54 | Turmeric | 1件: Turmeric Turmeric | - | - | - | 4件: 140 140, 144, 158, 299 |
| 55 | ZX008 | - | - | - | - | 2件: 140 140, 144 |
| 56 | ZX008 (Fenfluramine Hydrochloride) | 1件: Fenfluramine Fenfluramine | 1件: D07945
D07945
| 4件: HTR2A HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 | 6件: Calcium signaling pathway Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | 2件: 140 140, 144 |
| 57 | ZX008 0.2 or 0.8 mg/kg/day | - | - | - | - | 1件: 144 144 |
| 58 | ZX008 0.2 to 0.8 mg/kg/day | - | - | - | - | 2件: 140 140, 144 |