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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1(7R,8R,9R)-2.3-Dimethyl-8-hydroxy-7(2-methoxyethoxy)- 9-phenyl-7.8.9.10-tetrahydro-imidazo-[1.2-h].[1.7].- naphthyridine----1件: 301
24-Methylpyrazole1件: Fomepizole1件: D00707 3件: ADH1A,
ADH1B,
ADH1C 💬		9件: Alcoholic liver disease, Drug metabolism - cytochrome P450, Fatty acid degradation, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pyruvate metabolism, Retinol metabolism, Tyrosine metabolism 💬1件: 301
3ACU-4429----1件: 301
4ALK-001----1件: 301
5ALK-001 (No generic name)----1件: 301
6ARC1905----1件: 301
7ARC1905 20 MG/ML----1件: 301
8Avacincaptad pegol1件: Avacincaptad pegol---1件: 301
9DHA----8件: 6, 46, 48, 49, 94, 113, 299, 301
10Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)----2件: 90, 301
11Docosahexaenoic acid1件: Doconexent---7件: 6, 49, 90, 94, 240, 299, 301
12Docosahexaenoic Acid (DHA) Dietary Supplement1件: Doconexent---1件: 301
13Emixustat1件: Emixustat1件: D10348 --1件: 301
14Emixustat hydrochloride1件: Emixustat1件: D10348 --1件: 301
15EMIXUSTAT HYDROCHLORIDE (ACU-4429)1件: Emixustat1件: D10348 --1件: 301
16EPA----6件: 8, 46, 48, 49, 113, 301
17EU/3/13/1208 orphan----1件: 301
18HESC-RPE----1件: 301
19Interferon Gamma1件: Interferon Gamma---8件: 18, 65, 85, 107, 228, 299, 301, 326
20INTERFERON GAMMA-1B2件: Interferon Gamma,
Interferon gamma-1b		1件: D00747 2件: IFNGR1,
IFNGR2 💬		18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬7件: 18, 65, 85, 228, 299, 301, 326
21Lentiviral vector containing ABCA4 gene----1件: 301
22Long term follow up in all patients who received SAR422459 in previous study TDU13583----1件: 301
23MA09-hRPE----1件: 301
24Madeos----1件: 301
25Metformin1件: Metformin2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
26METFORMIN HYDROCHLORIDE1件: Metformin2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬5件: 81, 158, 265, 299, 301
27Other: Saline----8件: 2, 6, 46, 97, 98, 256, 274, 301
28Other: Sham----1件: 301
29Other: Standard of Care Sildenafil1件: Sildenafil2件: D02229 ,
D08514 		1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 90, 301
30Other: Visual Acuity (VA)----2件: 90, 301
31Over the counter DHA/EPA dietary supplementation----1件: 301
32Ranibizumab1件: Ranibizumab1件: D05697 1件: VEGFA 💬24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬4件: 34, 166, 227, 301
33Ranibizumab injection (0.5 mg)1件: Ranibizumab1件: D05697 1件: VEGFA 💬24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 166, 301
34Saffron supplementation----1件: 301
35SAR422459----1件: 301
36Sildenafil1件: Sildenafil2件: D02229 ,
D08514 		1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
37SORAPRAZAN----1件: 301
38StarGen----1件: 301
39Stem/progenitor cells transplantation----2件: 90, 301
40STG-0011件: STG-001---1件: 301
41Tinlarebant----1件: 301
42VA----3件: 90, 301, 302
43Vett Lentiviral con gene ABCA4----1件: 301
44Zimura----1件: 301