Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	HDAC6	4件: Neutrophil extracellular trap formation, Amyotrophic lateral sclerosis, Alcoholism, Viral carcin ...	D06320	Vorinostat	3件: 19, 75, 96
2	HDAC5	5件: Apelin signaling pathway, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogene ...	D06320	Vorinostat	3件: 19, 75, 96
3	CD52	-	D02802	Alemtuzumab	20件: 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
4	CHRM1	8件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D00397	Tropicamide	3件: 6, 13, 19
5	CHRM2	6件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D00397	Tropicamide	3件: 6, 13, 19
6	CHRM3	11件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste ...	D00397	Tropicamide	3件: 6, 13, 19
7	CHRM4	3件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton	D00397	Tropicamide	3件: 6, 13, 19
8	CHRM5	6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulat ...	D00397	Tropicamide	3件: 6, 13, 19
9	TPP1	1件: Lysosome	D10813	Cerliponase alfa	1件: 19
10	CSF3R	5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03247	Lenograstim	7件: 2, 13, 16, 18, 19, 57, 65

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