Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
2 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
4 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
5 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
6 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
7 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
8 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA2D1 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
9 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
10 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
11 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
12 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
13 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
14 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
15 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
16 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
HDAC1 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
17 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
18 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
19 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
20 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
21 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
22 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
23 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
24 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
25 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
26 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
27 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
28 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
29 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
30 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
31 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
32 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
33 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
34 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
HDAC6 1件: HDAC6 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
35 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
36 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
37 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
38 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
39 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
40 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
41 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
42 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
43 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
44 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
45 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
46 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
HDAC4 2件: HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
47 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
48 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
49 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
50 | Apoptosis - multiple species 💬 Related to 3 target genes, 3 drugs (DrugBank) and 9 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
51 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA2D1 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
52 | Ascorbate and aldarate metabolism 💬 Related to 1 target gene, 1 drug (DrugBank) and 1 disease in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
53 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
54 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
55 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
56 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 42 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
57 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
58 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
59 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
60 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
61 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
62 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
63 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
64 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
65 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
66 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
67 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
68 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
69 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
70 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
71 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
72 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
73 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 4件: CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
74 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
75 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
76 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
77 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA2D1 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
78 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
79 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
80 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
81 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
82 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
83 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
84 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
85 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
86 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
87 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
88 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE 1件: ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
89 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE 1件: ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
90 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE 1件: ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
91 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE 1件: ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
92 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE 1件: ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 1件: 19 💬 |
93 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE 1件: ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 1件: 19 💬 |
94 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
95 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
96 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
97 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
98 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
99 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 25件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
100 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR 1件: VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 4件: 19, 66, 218, 238 💬 |
101 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
102 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
LIPA 1件: LIPA 💬 |
D10377 D10377 💬 |
Sebelipase alfa | 019 1件: 19 💬 |
103 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
104 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
105 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
106 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
107 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
108 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE 1件: ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
109 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE 1件: ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
110 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE 1件: ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
111 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE 1件: ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
112 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE 1件: ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 1件: 19 💬 |
113 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE 1件: ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 1件: 19 💬 |
114 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
115 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
116 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
117 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
118 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
119 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
120 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
121 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
122 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
123 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
124 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
125 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
126 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
127 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
128 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
129 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
130 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
131 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
132 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
133 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
134 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
135 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
136 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 1件: 19 💬 |
137 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 1件: 19 💬 |
138 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
139 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
140 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
141 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
142 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
143 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
CACNA2D1 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
144 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
145 | DNA replication 💬 Related to 2 target genes, 1 drug (DrugBank) and 9 diseases in DDrare |
POLA1 2件: POLA1, POLA2 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
146 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
147 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
148 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
149 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
150 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
151 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
152 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
153 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
154 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
155 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
156 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
157 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 25件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
158 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 4件: 19, 66, 218, 238 💬 |
159 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
160 | Endocytosis 💬 Related to 21 target genes, 28 drugs (DrugBank) and 53 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
161 | Endocytosis 💬 Related to 21 target genes, 28 drugs (DrugBank) and 53 diseases in DDrare |
TFRC 1件: TFRC 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
162 | Endometrial cancer 💬 Related to 10 target genes, 15 drugs (DrugBank) and 21 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
163 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
164 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
165 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
166 | ErbB signaling pathway 💬 Related to 12 target genes, 22 drugs (DrugBank) and 52 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
167 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
168 | Ferroptosis 💬 Related to 2 target genes, 2 drugs (DrugBank) and 2 diseases in DDrare |
TFRC 1件: TFRC 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
169 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
170 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
171 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
172 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
173 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
174 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
175 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
176 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare |
SLC6A1 1件: SLC6A1 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
177 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GLA 1件: GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 1件: 19 💬 |
178 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GLA 1件: GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 1件: 19 💬 |
179 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
180 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
181 | Glioma 💬 Related to 14 target genes, 26 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
182 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
183 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
184 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 26 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
185 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 26 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
186 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 26 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
187 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 26 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
188 | Glycerolipid metabolism 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA 1件: GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 1件: 19 💬 |
189 | Glycerolipid metabolism 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA 1件: GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 1件: 19 💬 |
190 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
ARSB 1件: ARSB 💬 |
D06565 D06565 💬 |
Galsulfase | 019 1件: 19 💬 |
191 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
GALNS 1件: GALNS 💬 |
D10333 D10333 💬 |
Elosulfase alfa | 019 1件: 19 💬 |
192 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
193 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDS 1件: IDS 💬 |
D04499 D04499 💬 |
Idursulfase | 019 1件: 19 💬 |
194 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDS 1件: IDS 💬 |
D11025 D11025 💬 |
Idursulfase beta | 019 1件: 19 💬 |
195 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDS 1件: IDS 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
196 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDUA 1件: IDUA 💬 |
D04670 D04670 💬 |
Laronidase | 019 2件: 19, 256 💬 |
197 | Glycosphingolipid biosynthesis - globo and isoglobo series 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA 1件: GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 1件: 19 💬 |
198 | Glycosphingolipid biosynthesis - globo and isoglobo series 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA 1件: GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 1件: 19 💬 |
199 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
200 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
201 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
202 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
203 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
204 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
205 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
MS4A1 1件: MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 006 49件: 6 , 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
206 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TFRC 1件: TFRC 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
207 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
208 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
209 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
210 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
211 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
212 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
213 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
214 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
215 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
216 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
217 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
218 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
219 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
220 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
TFRC 1件: TFRC 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
221 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
222 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
223 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
224 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
225 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
226 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
227 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
228 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
229 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
230 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
231 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
232 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
233 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
234 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
235 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
236 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
237 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
238 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
239 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
240 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
241 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
242 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
243 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE 1件: ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
244 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE 1件: ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
245 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE 1件: ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
246 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE 1件: ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
247 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE 1件: ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 1件: 19 💬 |
248 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE 1件: ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 1件: 19 💬 |
249 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
CACNA2D1 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
250 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
251 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
252 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
253 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
254 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
TRPV1 1件: TRPV1 💬 |
D00250 D00250 💬 |
Capsaicin | 002 5件: 2 , 6 , 19, 86, 226 💬 |
255 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
256 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
257 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
258 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
259 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
260 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
261 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
262 | Insulin signaling pathway 💬 Related to 12 target genes, 24 drugs (DrugBank) and 64 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
263 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
264 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
265 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
266 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
267 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
268 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
269 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
270 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
271 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
272 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
273 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
274 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
275 | Leukocyte transendothelial migration 💬 Related to 12 target genes, 12 drugs (DrugBank) and 27 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
276 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
277 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
278 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
279 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
280 | Longevity regulating pathway 💬 Related to 11 target genes, 18 drugs (DrugBank) and 65 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
281 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 14 drugs (DrugBank) and 59 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
282 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 14 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
283 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
ARSB 1件: ARSB 💬 |
D06565 D06565 💬 |
Galsulfase | 019 1件: 19 💬 |
284 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GALNS 1件: GALNS 💬 |
D10333 D10333 💬 |
Elosulfase alfa | 019 1件: 19 💬 |
285 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GBA 1件: GBA 💬 |
D02810 D02810 💬 |
Alglucerase | 019 1件: 19 💬 |
286 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GBA 1件: GBA 💬 |
D03020 D03020 💬 |
Imiglucerase | 019 1件: 19 💬 |
287 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GBA 1件: GBA 💬 |
D09675 D09675 💬 |
Taliglucerase alfa | 019 1件: 19 💬 |
288 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GBA 1件: GBA 💬 |
D09029 D09029 💬 |
Velaglucerase alfa | 019 1件: 19 💬 |
289 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GLA 1件: GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 1件: 19 💬 |
290 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GLA 1件: GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 1件: 19 💬 |
291 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
292 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
IDS 1件: IDS 💬 |
D04499 D04499 💬 |
Idursulfase | 019 1件: 19 💬 |
293 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
IDS 1件: IDS 💬 |
D11025 D11025 💬 |
Idursulfase beta | 019 1件: 19 💬 |
294 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
IDS 1件: IDS 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
295 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
IDUA 1件: IDUA 💬 |
D04670 D04670 💬 |
Laronidase | 019 2件: 19, 256 💬 |
296 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
LIPA 1件: LIPA 💬 |
D10377 D10377 💬 |
Sebelipase alfa | 019 1件: 19 💬 |
297 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
MAN2B1 1件: MAN2B1 💬 |
D11024 D11024 💬 |
Velmanase alfa | 019 1件: 19 💬 |
298 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
SMPD1 1件: SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 1件: 19 💬 |
299 | Lysosome 💬 Related to 13 target genes, 23 drugs (DrugBank) and 4 diseases in DDrare |
TPP1 1件: TPP1 💬 |
D10813 D10813 💬 |
Cerliponase alfa | 019 1件: 19 💬 |
300 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
301 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA2D1 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
302 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
303 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
304 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
305 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
306 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ARSB 1件: ARSB 💬 |
D06565 D06565 💬 |
Galsulfase | 019 1件: 19 💬 |
307 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
308 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
309 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
310 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
311 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GALNS 1件: GALNS 💬 |
D10333 D10333 💬 |
Elosulfase alfa | 019 1件: 19 💬 |
312 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA 1件: GBA 💬 |
D02810 D02810 💬 |
Alglucerase | 019 1件: 19 💬 |
313 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA 1件: GBA 💬 |
D03020 D03020 💬 |
Imiglucerase | 019 1件: 19 💬 |
314 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA 1件: GBA 💬 |
D09675 D09675 💬 |
Taliglucerase alfa | 019 1件: 19 💬 |
315 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA 1件: GBA 💬 |
D09029 D09029 💬 |
Velaglucerase alfa | 019 1件: 19 💬 |
316 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GLA 1件: GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 1件: 19 💬 |
317 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GLA 1件: GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 1件: 19 💬 |
318 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
319 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDS 1件: IDS 💬 |
D04499 D04499 💬 |
Idursulfase | 019 1件: 19 💬 |
320 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDS 1件: IDS 💬 |
D11025 D11025 💬 |
Idursulfase beta | 019 1件: 19 💬 |
321 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDS 1件: IDS 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
322 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDUA 1件: IDUA 💬 |
D04670 D04670 💬 |
Laronidase | 019 2件: 19, 256 💬 |
323 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
324 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
325 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
326 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
327 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
328 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
329 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
330 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
331 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
332 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
333 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
334 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
SMPD1 1件: SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 1件: 19 💬 |
335 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D09893 D09893 💬 |
Eliglustat | 019 1件: 19 💬 |
336 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D11439 D11439 💬 |
Lucerastat | 019 1件: 19 💬 |
337 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D05032 D05032 💬 |
Miglustat | 019 3件: 19, 256, 299 💬 |
338 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D11633 D11633 💬 |
Venglustat | 006 3件: 6 , 19, 67 💬 |
339 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
HDAC1 4件: HDAC1, HDAC2, HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
340 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
341 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 25件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
342 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR 1件: VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 4件: 19, 66, 218, 238 💬 |
343 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
344 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
345 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
346 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
347 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
SMPD1 1件: SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 1件: 19 💬 |
348 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
349 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
350 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
351 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
352 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
353 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
354 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
355 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
356 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
357 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
358 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
359 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
360 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
361 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 48件: 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
362 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
THRA 2件: THRA, THRB 💬 |
D01010 D01010 💬 |
Levothyroxine | 019 5件: 19, 49, 78, 80, 222 💬 |
363 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
THRA 2件: THRA, THRB 💬 |
D08125 D08125 💬 |
Levothyroxine | 019 5件: 19, 49, 78, 80, 222 💬 |
364 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
TRPV1 1件: TRPV1 💬 |
D00250 D00250 💬 |
Capsaicin | 002 5件: 2 , 6 , 19, 86, 226 💬 |
365 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
HDAC1 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
366 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
367 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
368 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
369 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
370 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
371 | Non-small cell lung cancer 💬 Related to 20 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
372 | Notch signaling pathway 💬 Related to 7 target genes, 3 drugs (DrugBank) and 5 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
373 | One carbon pool by folate 💬 Related to 3 target genes, 3 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
374 | One carbon pool by folate 💬 Related to 3 target genes, 3 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
375 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
376 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
377 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
378 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
379 | Other glycan degradation 💬 Related to 2 target genes, 5 drugs (DrugBank) and 1 disease in DDrare |
GBA 1件: GBA 💬 |
D02810 D02810 💬 |
Alglucerase | 019 1件: 19 💬 |
380 | Other glycan degradation 💬 Related to 2 target genes, 5 drugs (DrugBank) and 1 disease in DDrare |
GBA 1件: GBA 💬 |
D03020 D03020 💬 |
Imiglucerase | 019 1件: 19 💬 |
381 | Other glycan degradation 💬 Related to 2 target genes, 5 drugs (DrugBank) and 1 disease in DDrare |
GBA 1件: GBA 💬 |
D09675 D09675 💬 |
Taliglucerase alfa | 019 1件: 19 💬 |
382 | Other glycan degradation 💬 Related to 2 target genes, 5 drugs (DrugBank) and 1 disease in DDrare |
GBA 1件: GBA 💬 |
D09029 D09029 💬 |
Velaglucerase alfa | 019 1件: 19 💬 |
383 | Other glycan degradation 💬 Related to 2 target genes, 5 drugs (DrugBank) and 1 disease in DDrare |
MAN2B1 1件: MAN2B1 💬 |
D11024 D11024 💬 |
Velmanase alfa | 019 1件: 19 💬 |
384 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
CACNA2D1 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
385 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
386 | p53 signaling pathway 💬 Related to 5 target genes, 4 drugs (DrugBank) and 13 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
387 | p53 signaling pathway 💬 Related to 5 target genes, 4 drugs (DrugBank) and 13 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
388 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
389 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
390 | Pancreatic secretion 💬 Related to 12 target genes, 38 drugs (DrugBank) and 39 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
391 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 25件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
392 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
VDR 1件: VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 4件: 19, 66, 218, 238 💬 |
393 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
394 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
395 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
396 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
397 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
398 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
399 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
400 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
401 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
402 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
403 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
404 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
405 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
406 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
407 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
408 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
409 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
410 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
411 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
412 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
413 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
414 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
415 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
416 | Pentose and glucuronate interconversions 💬 Related to 1 target gene, 1 drug (DrugBank) and 1 disease in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
417 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
418 | Phagosome 💬 Related to 33 target genes, 11 drugs (DrugBank) and 24 diseases in DDrare |
TFRC 1件: TFRC 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
419 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
420 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
421 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
422 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
423 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
424 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
425 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
426 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
427 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
428 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
429 | Platinum drug resistance 💬 Related to 9 target genes, 13 drugs (DrugBank) and 22 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
430 | Porphyrin metabolism 💬 Related to 5 target genes, 4 drugs (DrugBank) and 2 diseases in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
431 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
432 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
433 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
434 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
435 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
436 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
437 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
438 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
439 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
440 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
441 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
442 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
443 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
444 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
445 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
446 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
447 | Pyrimidine metabolism 💬 Related to 4 target genes, 8 drugs (DrugBank) and 36 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
448 | Pyrimidine metabolism 💬 Related to 4 target genes, 8 drugs (DrugBank) and 36 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
449 | Pyrimidine metabolism 💬 Related to 4 target genes, 8 drugs (DrugBank) and 36 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
450 | Pyrimidine metabolism 💬 Related to 4 target genes, 8 drugs (DrugBank) and 36 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
451 | Regulation of actin cytoskeleton 💬 Related to 27 target genes, 54 drugs (DrugBank) and 57 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
452 | Regulation of actin cytoskeleton 💬 Related to 27 target genes, 54 drugs (DrugBank) and 57 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
453 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE 1件: ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
454 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE 1件: ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
455 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE 1件: ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
456 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE 1件: ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
457 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE 1件: ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 1件: 19 💬 |
458 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE 1件: ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 1件: 19 💬 |
459 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
460 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
461 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
462 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
463 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
464 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE 1件: ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
465 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE 1件: ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
466 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE 1件: ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
467 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE 1件: ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
468 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE 1件: ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 1件: 19 💬 |
469 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE 1件: ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 1件: 19 💬 |
470 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
471 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
472 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
473 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
474 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
475 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
476 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
477 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
478 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
479 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
480 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
481 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
482 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
483 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
GBA 1件: GBA 💬 |
D02810 D02810 💬 |
Alglucerase | 019 1件: 19 💬 |
484 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
GBA 1件: GBA 💬 |
D03020 D03020 💬 |
Imiglucerase | 019 1件: 19 💬 |
485 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
GBA 1件: GBA 💬 |
D09675 D09675 💬 |
Taliglucerase alfa | 019 1件: 19 💬 |
486 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
GBA 1件: GBA 💬 |
D09029 D09029 💬 |
Velaglucerase alfa | 019 1件: 19 💬 |
487 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
GLA 1件: GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 1件: 19 💬 |
488 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
GLA 1件: GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 1件: 19 💬 |
489 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
SMPD1 1件: SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 1件: 19 💬 |
490 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D09893 D09893 💬 |
Eliglustat | 019 1件: 19 💬 |
491 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D11439 D11439 💬 |
Lucerastat | 019 1件: 19 💬 |
492 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D05032 D05032 💬 |
Miglustat | 019 3件: 19, 256, 299 💬 |
493 | Sphingolipid metabolism 💬 Related to 4 target genes, 11 drugs (DrugBank) and 5 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D11633 D11633 💬 |
Venglustat | 006 3件: 6 , 19, 67 💬 |
494 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
SMPD1 1件: SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 1件: 19 💬 |
495 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
496 | Spinocerebellar ataxia 💬 Related to 16 target genes, 23 drugs (DrugBank) and 68 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
497 | Steroid biosynthesis 💬 Related to 1 target gene, 1 drug (DrugBank) and 1 disease in DDrare |
LIPA 1件: LIPA 💬 |
D10377 D10377 💬 |
Sebelipase alfa | 019 1件: 19 💬 |
498 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 39 diseases in DDrare |
SLC6A1 1件: SLC6A1 💬 |
D00332 D00332 💬 |
Gabapentin | 006 5件: 6 , 13, 19, 70, 298 💬 |
499 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
500 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
501 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
502 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
503 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
504 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
505 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
506 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
507 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
508 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
509 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
510 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
511 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
512 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
513 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
HDAC1 3件: HDAC1, HDAC2, HDAC3 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
514 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
515 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRA 2件: THRA, THRB 💬 |
D01010 D01010 💬 |
Levothyroxine | 019 5件: 19, 49, 78, 80, 222 💬 |
516 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRA 2件: THRA, THRB 💬 |
D08125 D08125 💬 |
Levothyroxine | 019 5件: 19, 49, 78, 80, 222 💬 |
517 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
518 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
519 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
520 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
521 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
522 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
523 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
524 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
525 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
526 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
527 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
528 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR 1件: VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 25件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
529 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR 1件: VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 4件: 19, 66, 218, 238 💬 |
530 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
531 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
532 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
533 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
534 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 Related to 3 target genes, 3 drugs (DrugBank) and 16 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
535 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 Related to 3 target genes, 3 drugs (DrugBank) and 16 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
536 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 Related to 3 target genes, 3 drugs (DrugBank) and 16 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
537 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
538 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
539 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
540 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
541 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
542 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
543 | Viral carcinogenesis 💬 Related to 31 target genes, 22 drugs (DrugBank) and 43 diseases in DDrare |
HDAC1 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
544 | Viral myocarditis 💬 Related to 30 target genes, 20 drugs (DrugBank) and 47 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
545 | Viral myocarditis 💬 Related to 30 target genes, 20 drugs (DrugBank) and 47 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
546 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
547 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
548 | Wnt signaling pathway 💬 Related to 8 target genes, 8 drugs (DrugBank) and 60 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
549 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |